Astrocytes & Huntington’s Disease (MDS)

Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.

September 19, 2019

Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics
Jordi Creus-Muncunill, Michelle E Ehrlich
February 5, 2020
Open Access

The Potential Role of Astrocytes in Parkinson's Disease (PD)

Medical Sciences : Open Access Journal
Hiluf Hindeya Gebreyesus, Teklu Gebrehiwot Gebremichael
April 1, 2020

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice

Journal of Visualized Experiments : JoVE
Anton Dvorzhak, Rosemarie Grantyn
October 25, 2019
Open Access

Transgenic minipig model of Huntington's disease exhibiting gradually progressing neurodegeneration

Disease Models & Mechanisms
Taras ArdanZdenka Ellederová
May 16, 2020
Open Access

Interstitial ions: A key regulator of state-dependent neural activity?

Progress in Neurobiology
Rune RasmussenMaiken Nedergaard
September 1, 2019

Astrocytes: From the Physiology to the Disease

Current Alzheimer Research
Laura Trujillo-EstradaFrank M LaFerla
August 8, 2020
Open Access

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene

The Journal of Biological Chemistry
Jeong Su ByunBaek-Soo Han
June 14, 2019

Brain iron transport

Biological Reviews of the Cambridge Philosophical Society
Zhong-Ming Qian, Ya Ke
December 25, 2019
Open Access

Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases

Journal of Lipid Research
Sara GrassiAlessandro Prinetti
July 19, 2019
Open Access

Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support

Frontiers in Neuroscience
Veronica J GarciaVirginia B Mattis
July 28, 2020
Open Access

Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes

International Journal of Molecular Sciences
Ching-On Wong
June 17, 2020

Astrocyte signaling gates long-term depression at corticostriatal synapses of the direct pathway

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Anna CavacciniAlfonso Araque
July 15, 2020
Open Access

The role of glia in protein aggregation

Neurobiology of Disease
Qingyun Li, Michael S Haney
September 19, 2020

C-terminal-dependent control of EAAT2 signaling, corticostriatal synaptic glutamate clearance and spontaneous motor activity in mice with hypokinesia

BioRxiv : the Preprint Server for Biology
S. HirschbergRosemarie Grantyn
August 11, 2019

Huntington's Disease: Astrocytes Shift to Fatty Acid Metabolism

Trends in Endocrinology and Metabolism : TEM
Bennett Van Houten
October 2, 2019
Open Access

Neuroinflammation as a Common Feature of Neurodegenerative Disorders

Frontiers in Pharmacology
Leonardo Guzman-MartinezNicolas Ramos-Escobar
April 5, 2020
Open Access

Role of Connexins 30, 36, and 43 in Brain Tumors, Neurodegenerative Diseases, and Neuroprotection

Oscar F SánchezSonia-Luz Albarracin
May 16, 2020

Dysregulated Brain Cholesterol Metabolism Is Linked to Neuroinflammation in Huntington's Disease

Movement Disorders : Official Journal of the Movement Disorder Society
Edith González-GuevaraJuan Carlos Martínez-Lazcano
November 12, 2019
Open Access

The Role of Microglia and Astrocytes in Huntington's Disease

Frontiers in Molecular Neuroscience
Thulani H PalpagamaAndrea Kwakowsky

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