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Ataxia telangiectasia

Ataxia telangiectasia diagram by Amariglio et al, PLOS Medicine
Amariglio et al, PLOS Medicine

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Non-BRCA DNA Damage Repair Gene Alterations and Response to the PARP Inhibitor Rucaparib in Metastatic Castration-Resistant Prostate Cancer: analysis from the phase 2 TRITON2 study

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchFebruary 23, 2020
Wassim AbidaSimon Chowdhury
6
Science Translational Medicine

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Science Translational MedicineFebruary 21, 2020
Florence CoussyElisabetta Marangoni
7
1
The EMBO Journal

SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres

The EMBO JournalFebruary 22, 2020
Aleksandra VančevskaJoachim Lingner
2
BioMed Research International

Development and Validation of a 34-Gene Inherited Cancer Predisposition Panel Using Next-Generation Sequencing

BioMed Research InternationalFebruary 25, 2020
Sun Hee RosenthalRenius Owen
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

α2δ-2 protein controls structure and function at the cerebellar climbing fiber synapse

The Journal of Neuroscience : the Official Journal of the Society for NeuroscienceFebruary 23, 2020
Kathleen A BeesonEric Schnell
Annals of Oncology : Official Journal of the European Society for Medical Oncology

ATM loss in NSCLC increases sensitivity to cisplatin and PARP inhibition

Annals of Oncology : Official Journal of the European Society for Medical OncologyFebruary 22, 2020
D G BebbS Lees-Miller
The Cerebellum

Founder Effects of Spinocerebellar Ataxias in the American Continents and the Caribbean

The CerebellumFebruary 23, 2020
Roberto Rodríguez-LabradaPanAmerican Hereditary Ataxia Network
1

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