Ataxia telangiectasia

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

October 17, 2021
Preprint
Open Access

Structure of the human ATM kinase and mechanism of Nbs1 binding

BioRxiv : the Preprint Server for Biology
C. Warren, Nikola P Pavletich
October 16, 2021

Germline Variants Identified in Patients with Early-onset Renal Cell Carcinoma Referred for Germline Genetic Testing.

European Urology Oncology
Hong TruongMaria I Carlo
October 16, 2021

Inherited Mutations in Chinese Men With Prostate Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN
Yao ZhuDingwei Ye
October 15, 2021

The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms.

Endocrine-related Cancer
Andreas VenizelosStian Knappskog
October 14, 2021

A Tale of Two Checkpoints: ATR Inhibition and PD-(L)1 Blockade.

Annual Review of Medicine
Natalie Y L NgoiTimothy A Yap
October 13, 2021

A pleiotropic ATM variant (rs1800057 C>G) is associated with risk of multiple cancers.

Carcinogenesis
Danwen QianQingyi Wei
October 13, 2021
Review

Penetrance of male breast cancer susceptibility genes: a systematic review.

Breast Cancer Research and Treatment
Reem S ChamseddineKevin S Hughes
October 13, 2021

An anaplerotic approach to correct the mitochondrial dysfunction in ataxia-telangiectasia (A-T).

Molecular Metabolism
A J YeoM F Lavin
October 13, 2021

Concurrent pathogenic variations in patients with hereditary cancer syndromes.

European Journal of Medical Genetics
Nihat Bugra Agaoglu, Levent Doganay
October 13, 2021

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.

Blood Advances
Marina Lafage-PochitaloffEric Delabesse
October 12, 2021
Preprint
Open Access

TRAIP regulates DNA double-strand break-induced ATM activation

BioRxiv : the Preprint Server for Biology
T. GleichDaniel Hohl
October 11, 2021

Genetic Risk Variants for Class Switching Recombination Defects in Ataxia-Telangiectasia Patients.

Journal of Clinical Immunology
Parisa AmirifarAsghar Aghamohammadi
October 9, 2021

Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study.

Cancer Prevention Research
C Sloane FurnissSapna Syngal
October 8, 2021
Open Access

A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions.

Frontiers in Cell and Developmental Biology
Maria LikhatchevaKaye J Williams

Sign up to follow this feed and discover related papers.

Related Feeds

Chronic Granulomatous Disease

Chronic Granulomatous Disease is an inherited immunodeficiency disorder that is characterized by recurrent infections and granuloma formation. Discover the latest research on Chronic Granulomatous Disease here.

Common Variable Immunodeficiency

Common variable immunodeficiency is a primary immunodeficiency disease characterized by hypogammaglobulinemia and lack of antibody production. Here is the latest research.

Deltaretrovirus Infections

Deltaretroviruses such as human T-lymphotropic virus type 1 and bovine leukemia virus induce a persistent infection that remains generally asymptomatic but can also lead to leukemia or lymphoma. Here is the latest research on Deltaretroviruses infections.


Epidemiology of HIV/AIDS

HIV/AIDS is a global pandemic with Sub-Saharan Africa being the most affected region. In 2017, almost 37 million people were infected with HIV and almost 1 million deaths occurred due to AIDS. Find the latest research on HIV/AIDS here.

HIV & Co-Infections

HIV co-infection worsens the histological course of other viral infections, such as HCV by increasing and accelerating the risk of cirrhosis or leading to rare but lethal fibrosing cholestatic hepatitis. Discover the latest research on HIV co-infection.

HIV & Nutrition

While good nutrition is important for all individuals, it is especially an important issue for those infected HIV for several reasons. HIV infection impacts metabolic, cardiovascular, and psychological functioning and nutrition is key in managing these changes. Find the latest research on HIV and nutrition here.

HIV Vaccine

The development to make HIV vaccines for both the prevention and treatment of HIV infection is ongoing. Some individuals with HIV infection produce antibodies which suppress the virus and allow the patients to remain asymptomatic, suggesting that a vaccine may be achievable. Find the latest research on HIV vaccines here.

HIV-1 Reverse Transcriptase

HIV-1 reverse transcriptase is among the earliest HIV proteins identified and is involved in viral replication. More than half of investigational long-acting antivirals target hiv-1 reverse transcriptase and/or integrase (hiv-1 in). Discover the latest research here.

HIV/AIDS-Related Malignancies

HIV/AIDS infection increases the risk of non-communicable diseases common in the aged including HIV/AIDS-related malignancies. Discover the latest research in HIV/AIDS-related malignancies.

HIV: Cell & Gene Therapy

This feed focuses on emerging cell and gene therapies, such as HIV vaccines, for treating patients living with HIV/AIDS. Discover the latest research here.

© 2021 Meta ULC. All rights reserved
/feed-previews/ataxia-telangiectasia/fcd53290-4f5b-450b-8eb9-594f98d457bd