Autism: Treatment Targets

The absence of effective treatments for autism are due to the high clinical and genetic heterogeneity between affected individuals, restricted knowledge of the underlying pathophysiological mechanisms, and the lack of reliable diagnostic biomarkers. Identification of more homogenous biological subgroups is therefore essential for the development of novel treatments based on the molecular mechanisms underpinning autism and autism spectrum disorders. Find the latest research on autism treatment targets here.

July 11, 2020

Social Determinants of Health and the Role of Routine Pediatric Care in a Medically Complex Toddler

Journal of Developmental and Behavioral Pediatrics : JDBP
Karen CuttinMarilyn Augustyn
August 15, 2020
Open Access

Properties of beta oscillations in Dup15q syndrome

Journal of Neurodevelopmental Disorders
Vidya SaravanapandianShafali S Jeste
September 3, 2020

Exposure to a high dose of amoxicillin causes behavioral changes and oxidative stress in young zebrafish

Metabolic Brain Disease
Cinara L GonçalvesEmilio L Streck
September 8, 2020
Review
Open Access

Mitochondrial Dysfunction in Autism Spectrum Disorder: Unique Abnormalities and Targeted Treatments

Seminars in Pediatric Neurology
Richard E Frye
September 3, 2020

Postoperative improvement of executive function and adaptive behavior in children with intractable epilepsy

Brain & Development
Riyo UedaMasumi Inagaki
July 18, 2020

Mothers' and Fathers' Perspectives on the Causes of Their Child's Disorder

Journal of Pediatric Psychology
Anna FelnhoferOswald D Kothgassner
September 9, 2020

MicroRNA-targeted signaling pathways in the Autism spectrum disorder: implications for early detection and targeted therapy

CNS & Neurological Disorders Drug Targets
Rasoul AlizadehMansoureh Akouchekian
July 29, 2020
Review

Optimizing Genetic Diagnosis of Neurodevelopmental Disorders in the Clinical Setting

Clinics in Laboratory Medicine
David Joshua Michelson, Robin Dawn Clark
September 6, 2020

SYNGAP1 Controls the Maturation of Dendrites, Synaptic Function, and Network Activity in Developing Human Neurons

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Nerea LlamosasGavin Rumbaugh
September 12, 2020
Open Access

Clinical and genetic characteristics of patients with Doose syndrome

Epilepsia Open
Nodoka HinokumaMitsuhiro Kato
August 8, 2020
Open Access

Clinical and genetic findings in Hungarian pediatric patients carrying chromosome 16p copy number variants and a review of the literature

European Journal of Medical Genetics
Anna LengyelIrén Haltrich
September 12, 2020

Endocrine Insights into the Pathophysiology of Autism Spectrum Disorder

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
Hayley A WilsonNeil J MacLusky
July 21, 2020
Review
Open Access

Cortico-basal ganglia circuits underlying dysfunctional control of motor behaviors in neuropsychiatric disorders

Current Opinion in Genetics & Development
Ana Mafalda VicenteRui M Costa
July 20, 2020
Review

Convergence and Divergence in the Genetics of Psychiatric Disorders From Pathways to Developmental Stages

Biological Psychiatry
Shahar ShohatSagiv Shifman
July 30, 2020
Open Access

Next Generation Sequencing of 134 Children with Autism Spectrum Disorder and Regression

Genes
Jiani YinElena L Grigorenko

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