Parkinson's Disease & Autophagy

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in Parkinson’s disease.

January 17, 2021
Open Access

Inhibition of mitochondrial complex II in neuronal cells triggers unique pathways culminating in autophagy with implications for neurodegeneration

Scientific Reports
Sathyanarayanan RanganayakiMuchukunte Mukunda Srinivas Bharath
November 24, 2020
Open Access

Autophagy and Redox Homeostasis in Parkinson's: A Crucial Balancing Act

Oxidative Medicine and Cellular Longevity
Natalia Jimenez-Moreno, Jon D Lane
January 3, 2021

Emerging and converging molecular mechanisms in dystonia

Journal of Neural Transmission
Paulina Gonzalez-LatapiNiccolò E Mencacci
November 22, 2020
Open Access

The Role of Cholesterol in α-Synuclein and Lewy Body Pathology in GBA1 Parkinson's Disease

Movement Disorders : Official Journal of the Movement Disorder Society
Patricia García-SanzRosario Moratalla
December 28, 2020
Open Access

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

BioRxiv : the Preprint Server for Biology
S. YangDaniel Colon-Ramos
December 22, 2020

Role of RhoA-ROCK signaling in Parkinson's disease

European Journal of Pharmacology
Mahalaxmi IyerBalachandar Vellingiri
December 15, 2020

Extracellular vesicles - propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases

Journal of Cell Science
Natasha VassileffAndrew F Hill
November 22, 2020
Open Access

Alternative mitochondrial quality control mediated by extracellular release

Chi-Jing ChoongHideki Mochizuki
December 18, 2020
Open Access

When Friendship Turns Sour: Effective Communication Between Mitochondria and Intracellular Organelles in Parkinson's Disease

Frontiers in Cell and Developmental Biology
Tsu-Kung LinTzu-Jou Wang
November 17, 2020

Mitochondria-ER Tethering in Neurodegenerative Diseases

Cellular and Molecular Neurobiology
Reza Raeisossadati, Merari F R Ferrari
November 18, 2020

Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain

The American Journal of Chinese Medicine
Wei-Ti HsuShih-Ya Hung
January 5, 2021
Open Access

Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms

Frontiers in Neuroscience
Xiangpeng Ren, Jiang-Fan Chen
December 4, 2020
Open Access

The Critical Role of SIRT1 in Parkinson's Disease: Mechanism and Therapeutic Considerations

Aging and Disease
Xuan LiYun-Cheng Wu
January 10, 2021
Open Access

The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity

Hagai Rottenberg, Jan B Hoek
December 20, 2020

Common aspects between glaucoma and brain neurodegeneration

Mutation Research
Sergio Claudio SaccàAlberto Izzotti

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