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Autophagy: Cancer & Parkinson

Autophagy: Cancer & Parkinson diagram by undefined

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

Top 20 most recent papers
Journal of Cell Science

Nutrient regulation of mTORC1 at a glance

Journal of Cell ScienceNovember 13, 2019
Kendall J Condon, David M. Sabatini
Scientific Reports

SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function

Scientific ReportsNovember 5, 2019
Aurélien SchwobChloé Journo
1
Autophagy

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects

AutophagyNovember 7, 2019
Oliver KeppGuido Kroemer
1
Autophagy

Identification of an AGO (Argonaute) protein as a prey of TER94/VCP

AutophagyNovember 12, 2019
Hotaka Kobayashi, Yukihide Tomari
1
Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology

Magnetic Hyperthermia Using Self-Controlled Heating Elements Consisting of Fe-Al Milling Alloy Induces Cancer Cell Apoptosis while Preserving Skeletal Muscle

Pathobiology : Journal of Immunopathology, Molecular and Cellular BiologyNovember 13, 2019
Isao KawaharaHiroki Kuniyasu
Cancers

Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer

CancersNovember 11, 2019
Cally J Ho, Sharon M Gorski
Journal of Molecular Neuroscience : MN

Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS

Journal of Molecular Neuroscience : MNNovember 12, 2019
Shaochun ZhuMiles Trupp
Autophagy

Allosteric regulation through a switch element in the autophagy E2, Atg3

AutophagyNovember 7, 2019
Yu QiuBrenda A. Schulman
International Journal of Molecular Sciences

Cachexia Anorexia Syndrome and Associated Metabolic Dysfunction in Peritoneal Metastasis

International Journal of Molecular SciencesOctober 31, 2019
Rami ArchidRobert Beaumont Wilson
Autophagy

BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis -infected macrophages through selective autophagy

AutophagyNovember 11, 2019
Shuxin LiangYong Zhang
3
JCI Insight

TSLP protects against liver I/R injury via activation of the PI3K/Akt pathway

JCI InsightNovember 14, 2019
Shilai LiTimothy R. Billiar
Molecular Cancer

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Molecular CancerNovember 11, 2019
Xinming JingYong-Qian Shu
2
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

Eriocalyxin B Induces Apoptosis and Autophagy Involving Akt/Mammalian Target of Rapamycin (mTOR) Pathway in Prostate Cancer Cells

Medical Science Monitor : International Medical Journal of Experimental and Clinical ResearchNovember 12, 2019
Zi-Qiang YuChao-Zhao Liang
PloS One

Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster

PloS OneNovember 12, 2019
Hongbin SiHansong Deng
3
Cell Death and Differentiation

Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload

Cell Death and DifferentiationNovember 4, 2019
Nicoletta PlotegherMichael Roland Duchen
5
1
Current Drug Targets

The therapeutic potential of quercetin in Parkinson's disease: Insights into its molecular and cellular regulation

Current Drug TargetsNovember 12, 2019
Omid Reza TamtajiZatollah Asemi
Aging

LHX2 promotes malignancy and inhibits autophagy via mTOR in osteosarcoma and is negatively regulated by miR-129-5p

AgingNovember 13, 2019
Honghai SongZhi-li Liu
International Wound Journal

Acidic pH derived from cancer cells as a double-edged knife modulates wound healing through DNA repair genes and autophagy

International Wound JournalNovember 11, 2019
Shadi Rabiee MotmaenMahmoud Barati
1
Neuroscience Letters

Reduced expression of dMyc mitigates TauV337M mediated neurotoxicity by preventing the Tau hyperphosphorylation and inducing autophagy in Drosophila

Neuroscience LettersNovember 9, 2019
PragatiSurajit Sarkar
2
Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie

Huganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest

Biomedicine & Pharmacotherapy = Biomédecine & PharmacothérapieNovember 4, 2019
Xue GaoXiao-Hong Pan

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