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Autophagy: Cancer & Parkinson

Autophagy: Cancer & Parkinson diagram by  Kateryna Kon, Shutterstock
Kateryna Kon, Shutterstock

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

Top 20 most recent papers
May 16, 2020

Arsenic Exposure and Compromised Protein Quality Control

Chemical Research in Toxicology
Lok Ming Tam, Yinsheng Wang
May 14, 2020
Comment / EditorialOpen Access

The LC3-conjugation machinery specifies cargo loading and secretion of extracellular vesicles

Autophagy
Elizabeth Delorme-Axford, Daniel J Klionsky
May 14, 2020

CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation

Autophagy
Christian W KellerJan D Lünemann
May 19, 2020
Review

Regulation and function of V-ATPases in physiology and disease

Biochimica Et Biophysica Acta. Biomembranes
Michael P Collins, Michael Forgac
May 14, 2020
Comment / EditorialOpen Access

New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16

Autophagy
Damián Gatica, Daniel J Klionsky
May 24, 2020
ReviewOpen Access

Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Grégoire QuinetManuel S Rodriguez
May 14, 2020

Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR Endosomal Transport

Autophagy
Jie HanHannah Rabinowich
May 20, 2020

Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders

Proceedings of the National Academy of Sciences of the United States of America
Yao-Cheng LiGeoffrey M Wahl
May 19, 2020

Regulation of autophagy by DNA G-quadruplexes

Autophagy
Pauline LejaultAndrey S Tsvetkov
May 16, 2020
ReviewOpen Access

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response

Frontiers in Immunology
Dongshan WanJunwei Hao
May 14, 2020
Open Access

TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response

Cells
Sandra Pisonero-VaqueroDiego Luis Medina
May 22, 2020

Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity

Proceedings of the National Academy of Sciences of the United States of America
Wei-Cheng LuEverett Stone

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