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Autophagy: Cancer & Parkinson
Kateryna Kon, ShutterstockAutophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.
Arsenic Exposure and Compromised Protein Quality Control
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles
Clinicopathological and prognostic significance of caveolin-1 and ATG4C expression in the epithelial ovarian cancer
The LC3-conjugation machinery specifies cargo loading and secretion of extracellular vesicles
Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation
Regulation and function of V-ATPases in physiology and disease
Construction and Validation of an Autophagy-Related Prognostic Risk Signature for Survival Predicting in Clear Cell Renal Cell Carcinoma Patients
L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus
New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16
Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy
Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR Endosomal Transport
Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders
Long Non-Coding RNA NNT-AS1 Contributes to Cisplatin Resistance via miR-1236-3p/ATG7 Axis in Lung Cancer Cells
LC3-associated phagocytosis in myeloid cells, a fireman that restrains inflammation and liver fibrosis, via immunoreceptor inhibitory signalling
The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy
Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response
Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity
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