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Autophagy: Cancer & Parkinson
Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.
Top 20 most recent papers
Nutrient regulation of mTORC1 at a glance
Journal of Cell ScienceNovember 13, 2019
Kendall J Condon, David M. Sabatini
SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function
Scientific ReportsNovember 5, 2019
Aurélien SchwobChloé Journo
1
A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects
AutophagyNovember 7, 2019
Oliver KeppGuido Kroemer
1
Identification of an AGO (Argonaute) protein as a prey of TER94/VCP
AutophagyNovember 12, 2019
Hotaka Kobayashi, Yukihide Tomari
1
Magnetic Hyperthermia Using Self-Controlled Heating Elements Consisting of Fe-Al Milling Alloy Induces Cancer Cell Apoptosis while Preserving Skeletal Muscle
Pathobiology : Journal of Immunopathology, Molecular and Cellular BiologyNovember 13, 2019
Isao KawaharaHiroki Kuniyasu
Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer
CancersNovember 11, 2019
Cally J Ho, Sharon M Gorski
Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS
Journal of Molecular Neuroscience : MNNovember 12, 2019
Shaochun ZhuMiles Trupp
Allosteric regulation through a switch element in the autophagy E2, Atg3
AutophagyNovember 7, 2019
Yu QiuBrenda A. Schulman
Cachexia Anorexia Syndrome and Associated Metabolic Dysfunction in Peritoneal Metastasis
International Journal of Molecular SciencesOctober 31, 2019
Rami ArchidRobert Beaumont Wilson
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis -infected macrophages through selective autophagy
AutophagyNovember 11, 2019
Shuxin LiangYong Zhang
3
TSLP protects against liver I/R injury via activation of the PI3K/Akt pathway
JCI InsightNovember 14, 2019
Shilai LiTimothy R. Billiar
Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Molecular CancerNovember 11, 2019
Xinming JingYong-Qian Shu
2
Eriocalyxin B Induces Apoptosis and Autophagy Involving Akt/Mammalian Target of Rapamycin (mTOR) Pathway in Prostate Cancer Cells
Medical Science Monitor : International Medical Journal of Experimental and Clinical ResearchNovember 12, 2019
Zi-Qiang YuChao-Zhao Liang
Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
PloS OneNovember 12, 2019
Hongbin SiHansong Deng
3
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
Cell Death and DifferentiationNovember 4, 2019
Nicoletta PlotegherMichael Roland Duchen
5
1
The therapeutic potential of quercetin in Parkinson's disease: Insights into its molecular and cellular regulation
Current Drug TargetsNovember 12, 2019
Omid Reza TamtajiZatollah Asemi
LHX2 promotes malignancy and inhibits autophagy via mTOR in osteosarcoma and is negatively regulated by miR-129-5p
AgingNovember 13, 2019
Honghai SongZhi-li Liu
Acidic pH derived from cancer cells as a double-edged knife modulates wound healing through DNA repair genes and autophagy
International Wound JournalNovember 11, 2019
Shadi Rabiee MotmaenMahmoud Barati
1
Reduced expression of dMyc mitigates TauV337M mediated neurotoxicity by preventing the Tau hyperphosphorylation and inducing autophagy in Drosophila
Neuroscience LettersNovember 9, 2019
PragatiSurajit Sarkar
2
Huganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest
Biomedicine & Pharmacotherapy = Biomédecine & PharmacothérapieNovember 4, 2019
Xue GaoXiao-Hong Pan