Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

August 1, 2020
Open Access

Role of Autophagy in Lung Inflammation

Frontiers in Immunology
Jacob D PainterOmid Akbari
August 3, 2020

Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease

International Review of Neurobiology
Michael F AlmeidaStephen T Kinsey
July 30, 2020
Open Access

Ailanthone: A novel potential drug for treating human cancer

Oncology Letters
Haixiang DingZhilong Yan
August 4, 2020
Open Access

The biological function of m6A demethylase ALKBH5 and its role in human disease

Cancer Cell International
Jinyan WangQuan'an Zhang
August 1, 2020

Berberine: A novel therapeutic strategy for cancer

Parisa SamadiMehdi Yousefi
August 3, 2020

Phosphatidylinositol-3-kinase-Akt pathway in negative-stranded RNA virus infection: a minireview

Archives of Virology
Javier BlancoIsabel Muñoz-Barroso
July 30, 2020

Biology, pathology, and therapeutic targeting of RAS

Advances in Cancer Research
J Matthew RhettJohn P O'Bryan
July 30, 2020

Helicobacter pylori promote inflammation and host defense through the cagA-dependent activation of mTORC1

Journal of Cellular Physiology
Guang-Jing FengKe Li
August 1, 2020

lncRNA ZNF649-AS1 Induces Trastuzumab Resistance by Promoting ATG5 Expression and Autophagy

Molecular Therapy : the Journal of the American Society of Gene Therapy
Mingli HanHuaying Dong
July 30, 2020
Open Access

CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Lingyu ZhuLei Zong
July 30, 2020

Vascular mimicry: Triggers, molecular interactions and in vivo models

Advances in Cancer Research
Stephen L WechmanPaul B Fisher
July 31, 2020

Lysosome-targeting chimaeras for degradation of extracellular proteins

Steven M BanikCarolyn R Bertozzi
August 4, 2020

The balancing act of NEET proteins: Iron, ROS, calcium and metabolism

Biochimica Et Biophysica Acta. Molecular Cell Research
Rachel NechushtaiRon Mittler
August 4, 2020

Differential capacity of CD90+ cells in autophagy activation following chemotherapy in hepatocellular carcinoma

Annals of Hepatology
Huy Q DoCaecilia Hc Sukowati

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