Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

May 28, 2020
Open Access

Cell-Scale Degradation of Peritumoural Extracellular Matrix Fibre Network and Its Role Within Tissue-Scale Cancer Invasion

Bulletin of Mathematical Biology
Robyn Shuttleworth, Dumitru Trucu
June 4, 2020

Autophagy in fibroblasts induced by cigarette smoke extract promotes invasion in lung cancer cells

International Journal of Cancer. Journal International Du Cancer
Hsin-Han HouChong-Jen Yu
June 5, 2020

Alternate-day fasting alleviates diabetes-induced glycolipid metabolism disorders: roles of FGF21 and bile acids

The Journal of Nutritional Biochemistry
Hongbo ZhangZhigang Liu
June 2, 2020

Molecular mechanisms of selective autophagy in Drosophila

International Review of Cell and Molecular Biology
Raksha GohelIoannis P Nezis
May 27, 2020

Microvesicles derived from squamous cell carcinoma induce cell death, autophagy and invasion of benign myoepithelial cells

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Elizabeth Ferreira MartinezLucas Novaes Teixeira
May 24, 2020
Open Access

Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Grégoire QuinetManuel S Rodriguez
May 28, 2020
Open Access

Emerging agents that target signaling pathways in cancer stem cells

Journal of Hematology & Oncology
Yue YangLufeng Zheng
May 31, 2020
Open Access

Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells

International Journal of Molecular Sciences
Yoshihiro TatsumiKiyohide Fujimoto
June 2, 2020
Open Access

The Long and the Short of PTEN in the Regulation of Mitophagy

Frontiers in Cell and Developmental Biology
Liming WangHan-Ming Shen

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