Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

May 28, 2020
Open Access

Cell-Scale Degradation of Peritumoural Extracellular Matrix Fibre Network and Its Role Within Tissue-Scale Cancer Invasion

Bulletin of Mathematical Biology
Robyn Shuttleworth, Dumitru Trucu
June 4, 2020

Autophagy in fibroblasts induced by cigarette smoke extract promotes invasion in lung cancer cells

International Journal of Cancer. Journal International Du Cancer
Hsin-Han HouChong-Jen Yu
June 5, 2020

Alternate-day fasting alleviates diabetes-induced glycolipid metabolism disorders: roles of FGF21 and bile acids

The Journal of Nutritional Biochemistry
Hongbo ZhangZhigang Liu
June 2, 2020

Molecular mechanisms of selective autophagy in Drosophila

International Review of Cell and Molecular Biology
Raksha GohelIoannis P Nezis
May 27, 2020

Microvesicles derived from squamous cell carcinoma induce cell death, autophagy and invasion of benign myoepithelial cells

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Elizabeth Ferreira MartinezLucas Novaes Teixeira
May 24, 2020
Review
Open Access

Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Grégoire QuinetManuel S Rodriguez
May 28, 2020
Review
Open Access

Emerging agents that target signaling pathways in cancer stem cells

Journal of Hematology & Oncology
Yue YangLufeng Zheng
May 31, 2020
Open Access

Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells

International Journal of Molecular Sciences
Yoshihiro TatsumiKiyohide Fujimoto
June 2, 2020
Review
Open Access

The Long and the Short of PTEN in the Regulation of Mitophagy

Frontiers in Cell and Developmental Biology
Liming WangHan-Ming Shen

Sign up to follow this feed and discover related papers.

Related Feeds

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Aging Epidemiology

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

Aging Genetics

This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

Antidiabetic Cellular Plasticity

This feed focuses on mechanisms that underlie cellular plasticity as a treatment for diabetes and other degenerative diseases.

ApoE Phenotypes

Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Apoptotic Caspases

Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.

© 2020 Meta ULC. All rights reserved
/feed-previews/autophagy-metabolism/a11e430f-af9b-40b1-a19d-295a03b4a753