Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

January 16, 2022
Review

The complexity of biological control systems: An autophagy case study.

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Mariana PavelDavid C Rubinsztein
January 15, 2022
Review

Nanomedicine potentiates mild photothermal therapy for tumor ablation.

Asian Journal of Pharmaceutical Sciences
Zijun JiangYang Ding
January 15, 2022

SRT1720 induces SIRT1-independent cell death in adult T-cell leukemia/lymphoma.

The FEBS Journal
Tomohiro KozakoShin-Ichiro Honda
January 15, 2022

The complex interplay between autophagy and cell death pathways.

The Biochemical Journal
Christina PloumiNektarios Tavernarakis
January 15, 2022

Prognosis-related autophagy genes in female lung adenocarcinoma.

Medicine
Zhongxiang LiuHaicheng Tang
January 14, 2022

Boosting NAD+ blunts toll-like receptor-4 induced type-I interferon in control and systemic lupus erythematosus monocytes.

The Journal of Clinical Investigation
Jing WuMichael N Sack
January 14, 2022
Review

Autophagy Modulation and Cancer Combination Therapy: A Smart Approach in Cancer Therapy.

Cancer Treatment and Research Communications
Ali Salimi-JedaAsghar Abdoli
January 14, 2022

Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Xiaosong ZhangYanming Wei
January 14, 2022
Open Access

Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy.

Acta Pharmaceutica Sinica. B
Yancheng TangHu-Biao Chen
January 14, 2022
Review

Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls.

Acta Pharmaceutica Sinica. B
Hartmut JaeschkeAnup Ramachandran
January 14, 2022
Review

Autophagy: a molecular switch to regulate adipogenesis and lipolysis.

Molecular and Cellular Biochemistry
Mouliganesh Sekar, Kavitha Thirumurugan
January 14, 2022

Comprehensive Analysis of Tripterine Anti-Ovarian Cancer Effects Using Weighted Gene Co-Expression Network Analysis and Molecular Docking.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Xi LongJie Lin

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