Feed Preview

Autophagy Networks

Autophagy Networks diagram by Lin et al, PLOS One
Lin et al, PLOS One

Autophagy is a lysosomal pathway that involves degradation of proteins and functions in normal growth and pathological conditions, through a series of complex networks. The catabolic process involves delivery of proteins and organelles to the lysosome. Here is the latest research on autophagy networks.

Top 20 most recent papers
Nature Communications

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Nature CommunicationsJanuary 14, 2020
Jessica SegalésPura Muñoz-Cánoves
100
2
1
1
bioRxiv

Functional interaction between Fanconi anemia and mTOR pathways during stalled replication fork recovery

bioRxivJanuary 16, 2020
Matthew NolanIndrajit Chaudhury
7
bioRxiv

Beta-3 Adrenoreceptors protect from hypertrophic remodelling through AMP-Activated Protein Kinase and Autophagy.

bioRxivJanuary 14, 2020
Emilie Dubois-DeruyJean-Luc Balligand
4
Cells

Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington's Disease

CellsJanuary 17, 2020
Luisa VernizziPaola Bellosta
4
bioRxiv

Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

bioRxivJanuary 14, 2020
Yang JiaoJun Sun
3
Sub-cellular Biochemistry

Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis

Sub-cellular BiochemistryJanuary 16, 2020
Petra HänzelmannHermann Schindelin
Chemico-biological Interactions

Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model

Chemico-biological InteractionsJanuary 14, 2020
Qian GaoBin Yang
Vaccines

Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro

VaccinesJanuary 17, 2020
Zhiqiang HuRenyong Jia
ELife

Dynamic post-translational modification profiling of M. tuberculosis -infected primary macrophages

ELifeJanuary 18, 2020
Jonathan M BudzikJeffery S Cox
3
The Science of the Total Environment

IRE1 signaling pathway mediates protective autophagic response against manganese-induced neuronal apoptosis in vivo and in vitro

The Science of the Total EnvironmentJanuary 14, 2020
Chang LiuBin Xu
1
International Journal of Molecular Sciences

SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK

International Journal of Molecular SciencesJanuary 16, 2020
Tian ZhangLigen Lin
3
International Immunopharmacology

Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway

International ImmunopharmacologyJanuary 14, 2020
Ming XiaHong Liu
International Journal of Molecular Sciences

miR-218 Inhibits Mitochondrial Clearance by Targeting PRKN E3 Ubiquitin Ligase

International Journal of Molecular SciencesJanuary 18, 2020
Anthea Di RitaFlavie Strappazzon
1
bioRxiv

Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson's Disease Models

bioRxivJanuary 16, 2020
Vinita G Chittoor-VinodIan Martin
5
Molecular and Cellular Biochemistry

Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy

Molecular and Cellular BiochemistryJanuary 15, 2020
Thi Yen Ly HuynhJerzy Palka
International Journal of Clinical and Experimental Pathology

GSK-3β mediates ischemia-reperfusion injury by regulating autophagy in DCD liver allografts

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Tingting LiuYongfeng Liu
Journal of Dairy Science

Increased autophagy mediates the adaptive mechanism of the mammary gland in dairy cows with hyperketonemia

Journal of Dairy ScienceJanuary 14, 2020
Xinwei LiGuowen Liu
International Journal of Clinical and Experimental Pathology

Knockdown of lncRNA XIST suppresses osteosarcoma progression by inactivating AKT/mTOR signaling pathway by sponging miR-375-3p

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Xin SunJie-Cong Sun
Biomolecules

Sorafenib Inhibits Ribonucleotide Reductase Regulatory Subunit M2 (RRM2) in Hepatocellular Carcinoma Cells

BiomoleculesJanuary 16, 2020
Pei-Ming YangTsang-Pai Liu
Autophagy

Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells

AutophagyJanuary 17, 2020
Jun MatsudaYoshitaka Isaka

See more papers from this feed

Related Feeds

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Aging Epidemiology

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

Aging Genetics

This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

Apoptotic Caspases

Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.

Autophagosome

An autophagosome is the formation of double-membrane vesicles that involve numerous proteins and cytoplasmic components. These double-membrane vesicles are then terminated at the lysosome where they are degraded. Discover the latest research on autophagosomes here.

Autophagy & Aging: Inhibitors

The feed focuses on the role of nuclear export inhibitors and their effect on autophagy and the aging process.

Autophagy & Disease

Autophagy is an important cellular process for normal physiology and both elevated and decreased levels of autophagy are associated with disease. Here is the latest research.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

© 2020 Meta ULC. All rights reserved
/feed-previews/autophagy-networks/cd911a5a-c2fd-4f67-b9fe-a32ef0f94965