BCL-2 Family Proteins

BLC-2 family proteins are a group that share the same homologous BH domain. They play many different roles including pro-survival signals, mitochondria-mediated apoptosis and removal or damaged cells. They are often regulated by phosphorylation, affecting their catalytic activity. Here is the latest research on BCL-2 family proteins.

July 6, 2020

Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma

Immunologic Research
Hanan S AhmedManal M Elgerby
July 7, 2020

Perigastric solitary fibrous tumor (SFT) diagnosed on fine needle aspiration: A case report and review of literature

Diagnostic Cytopathology
Emad Ababneh, Maria Luisa C Policarpio-Nicolas
June 28, 2020

How intrinsic and extrinsic regulators of plasma cell survival might intersect for durable humoral immunity

Immunological Reviews
Marcus J RobinsonDavid M Tarlinton
July 1, 2020

Attenuation of cadmium-induced vascular toxicity by pro-angiogenic nanorods

Materials Science & Engineering. C, Materials for Biological Applications
Arpita RoyChitta Ranjan Patra
June 28, 2020

Allogeneic FLT3 CAR T Cells with an Off-Switch Exhibit Potent Activity against AML and Can Be Depleted to Expedite Bone Marrow Recovery

Molecular Therapy : the Journal of the American Society of Gene Therapy
Cesar SommerBarbra J Sasu
July 8, 2020
Open Access

Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax

Apoptosis : an International Journal on Programmed Cell Death
Bo WangYan Zhou
July 1, 2020

On the enigmatic disappearance of Rauber's layer

Proceedings of the National Academy of Sciences of the United States of America
Jessica van LeeuwenPeter L Pfeffer
July 2, 2020
Open Access

KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas

BioRxiv : the Preprint Server for Biology
James A HewardJ. Fitzgibbon
July 6, 2020

E3 ligase SCFSKP2 ubiquitinates and degrades tumor suppressor C/EBPα in acute myeloid leukemia

Life Sciences
Gatha ThackerArun Kumar Trivedi
July 1, 2020
Open Access

Paclitaxel induces apoptosis through the TAK1-JNK activation pathway

FEBS Open Bio
Yu-Wei DiYou-Wei Zheng
July 8, 2020
Open Access

Distinct Local and Systemic Molecular Signatures in the Esophageal and Gastric Cancers: Possible Therapy Targets and Biomarkers for Gastric Cancer

International Journal of Molecular Sciences
Iwona Bednarz-MisaMałgorzata Krzystek-Korpacka
July 1, 2020

circ_0080145 Enhances Imatinib Resistance of Chronic Myeloid Leukemia by Regulating miR-326/PPFIA1 Axis

Cancer Biotherapy & Radiopharmaceuticals
Hong CheXizhen Jia

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