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Biophysics of CRISPR

Biophysics of CRISPR diagram by StudioMolekuul, Shutterstock
StudioMolekuul, Shutterstock

This feed focuses on broad characteristics of the CRISPR system and the proteins associated with it.

Top 20 most recent papers
Nature Cell Biology

Programmable base editing of mutated TERT promoter inhibits brain tumour growth

Nature Cell BiologyFebruary 19, 2020
Xinjian LiZhimin Lu

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

ScienceMarch 29, 2020
Russell T WaltonBenjamin P Kleinstiver
Molecular Cell

CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures

Molecular CellMarch 7, 2020
Rodolphe Barrangou, Erik J Sontheimer
Nature Methods

Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies

Nature MethodsMarch 24, 2020
Nicole D MarinoJoseph Bondy-Denomy
Nature Plants

SpCas9-NG self-targets the sgRNA sequence in plant genome editing

Nature PlantsFebruary 26, 2020
Ruiying QinPengcheng Wei
The Journal of Physical Chemistry. B

CRISPR-CaS9 Genome Interrogation: A Facilitated Sub-Diffusive Target Search Strategy

The Journal of Physical Chemistry. BMarch 28, 2020
Diljith Thonnekottu, Debarati Chatterjee
The ISME Journal

Targeted assemblies of cas1 suggest CRISPR-Cas's response to soil warming

The ISME JournalMarch 30, 2020
Ruonan WuJames M Tiedje
The International Journal of Neuroscience

Common therapeutic advances for Duchenne muscular dystrophy (DMD)

The International Journal of NeuroscienceApril 4, 2020
Arash SalmaninejadMajid Mojarrad
Yi chuan = Hereditas

Next-generation CRISPR-Cas for genome editing: focusing on the Cas protein and PAM

Yi chuan = HereditasMarch 29, 2020
Lian Chao Tang, Feng Gu
Genome Biology

Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides

Genome BiologyFebruary 28, 2020
Yan-Ru CuiJia Liu
Briefings in Functional Genomics

Applications and advances of CRISPR/Cas9 in animal cancer model

Briefings in Functional GenomicsMarch 4, 2020
Min XuJiansong Ji
Sheng wu gong cheng xue bao = Chinese journal of biotechnology

Research progress and applications of gene editing technology CRISPR/Cas in zebrafish

Sheng wu gong cheng xue bao = Chinese journal of biotechnologyFebruary 20, 2020
Juan OuyangHengmi Cui
Toxicological Sciences : an Official Journal of the Society of Toxicology

Determining the biological mechanisms of action for environmental exposures: Applying CRISPR/Cas9 to toxicological assessments

Toxicological Sciences : an Official Journal of the Society of ToxicologyFebruary 28, 2020
Henry LujanChristie Sayes
Molecular Therapy. Methods & Clinical Development

Factors Impacting Efficacy of AAV-Mediated CRISPR-Based Genome Editing for Treatment of Choroidal Neovascularization

Molecular Therapy. Methods & Clinical DevelopmentMarch 5, 2020
Sook Hyun ChungGlenn Yiu

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