Biophysics of CRISPR

This feed focuses on broad characteristics of the CRISPR system and the proteins associated with it.

August 28, 2020
Open Access

Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA

Nature Biomedical Engineering
Maturada PatchsungChayasith Uttamapinant
September 3, 2020
Preprint
Open Access

Identification and evolution of Cas9 tracrRNAs

BioRxiv : the Preprint Server for Biology
S. K. DooleyJoshua K Young
August 22, 2020
Open Access

Targeted genome editing in tetraploid potato through transient TALEN expression by Agrobacterium infection

Plant Biotechnology
Shuhei YasumotoToshiya Muranaka
August 5, 2020

Knockdown the expression of ku70 and lig4 in HEK293T cells by CRISPR/Cas13 system

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Haoqiang WangDewu Liu
September 10, 2020
Open Access

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

Frontiers in Molecular Neuroscience
Joseph Edward RittinerBoris Kantor
August 9, 2020
Open Access

Development of a Highly Efficient Multiplex Genome Editing System in Outcrossing Tetraploid Alfalfa (Medicago sativa )

Frontiers in Plant Science
Tezera W WolabuZeng-Yu Wang
August 29, 2020

Molecular Mechanisms of CRISPR-Cas Immunity in Bacteria

Annual Review of Genetics
Philip M Nussenzweig, Luciano A Marraffini
August 25, 2020
Open Access

A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9

Science Advances
D ColliasC L Beisel
August 11, 2020
Review
Open Access

Ready for Repair? Gene Editing Enters the Clinic for the Treatment of Human Disease

Molecular Therapy. Methods & Clinical Development
Martijn P T ErnstW W M Pim Pijnappel
August 19, 2020

Creating CRISPR-responsive smart materials for diagnostics and programmable cargo release

Nature Protocols
Raphael V GayetJames J Collins
September 15, 2020

Chimeric DNA-RNA Guide RNA Designs

Methods in Molecular Biology
Shuhan LuHao Yin
August 21, 2020

Conditional Recruitment to a DNA-Bound CRISPR-Cas Complex Using a Colocalization-Dependent Protein Switch

ACS Synthetic Biology
Robin L KirkpatrickJesse G Zalatan
August 26, 2020

Invertase inhibitors in potato: towards a biochemical and molecular understanding of cold-induced sweetening

Critical Reviews in Food Science and Nutrition
Sagar S Datir
September 15, 2020
Review

CRISPR-Cas-mediated gene editing in lactic acid bacteria

Molecular Biology Reports
Xin SongLian-Zhong Ai
September 1, 2020
Open Access

Using CRISPR/ttLbCas12a for in planta Gene Targeting in A. thaliana

Current Protocols in Plant Biology
Laura MerkerHolger Puchta
September 18, 2020
Open Access

Unbiased investigation of specificities of prime editing systems in human cells

Nucleic Acids Research
Do Yon KimDaesik Kim

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