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Biophysics of CRISPR

Biophysics of CRISPR diagram by #N/A

This feed focuses on broad characteristics of the CRISPR system and the proteins associated with it.

Top 20 most recent papers

The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER

CellNovember 19, 2019
Robert Thomas SchinzelAndrew G Dillin
Nucleic Acids Research

Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing

Nucleic Acids ResearchDecember 4, 2019
Bin LiuHidde J Haisma

Mitotic spindle elongation is driven by joint microtubule sliding action of kinesins KIF4A and EG5

bioRxivDecember 3, 2019
Kruno VukušićIva M. Tolic

The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette

Machine Learning Predicts New Anti-CRISPR Proteins

bioRxivNovember 29, 2019
Simon EitzingerFayyaz ul Amir Afsar Minhas

Disrupting female flight in the vector Aedes aegypti

bioRxivDecember 2, 2019
Sarah O'Leary, Zach N. Adelman

Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations

bioRxivNovember 29, 2019
Lucie PoggiGuy-Franck Richard
Scientific Reports

An insulin-like growth factor-like peptide promotes ovarian development in the silkmoth Bombyx mori

Scientific ReportsDecember 5, 2019
Daiki FujinagaAkira Mizoguchi

Nanotopography enhances dynamic remodeling of tight junction proteins through cytosolic complexes

bioRxivNovember 28, 2019
Xiao HuangTejal A. Desai

In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia

CirculationNovember 29, 2019
Huan ZhaoBin Zhou
Molecular Therapy : the Journal of the American Society of Gene Therapy

GPR108 Is a Highly Conserved AAV Entry Factor

Molecular Therapy : the Journal of the American Society of Gene TherapyNovember 13, 2019
Amanda M DudekLuk H. Vandenberghe
Frontiers in Microbiology

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes )

Frontiers in MicrobiologyNovember 21, 2019
Thomas IpoutchaPascal Sirand-Pugnet
Clinical Epigenetics

Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function

Clinical EpigeneticsDecember 4, 2019
Verena DeutschmeyerAntje M Richter
The Journal of Allergy and Clinical Immunology

Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor

The Journal of Allergy and Clinical ImmunologyNovember 21, 2019
Keisuke KogaMakoto Tsuda
Cancer Research

Rare BRIP1 missense alleles confer risk for ovarian and breast cancer

Cancer ResearchDecember 10, 2019
Cassandra L MoyerPaul J Goodfellow
Plant Biotechnology Journal

Disruption of miRNA Sequences by TALENs and CRISPR/Cas9 Induces Varied Lengths of miRNA Production

Plant Biotechnology JournalDecember 10, 2019
Honghao BiBing Yang
Proceedings of the National Academy of Sciences of the United States of America

Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 5, 2019
Alex RosenbergL. David David Sibley
The Plant Journal : for Cell and Molecular Biology

Kmasker plants - a tool for assessing complex sequence space in plant species

The Plant Journal : for Cell and Molecular BiologyDecember 10, 2019
Sebastian BeierThomas Schmutzer
Microbial Cell Factories

Efficient Cas9-based genome editing of Rhodobacter sphaeroides for metabolic engineering

Microbial Cell FactoriesNovember 25, 2019
Ioannis MougiakosJohn van der Oost
Journal of Clinical Medicine

The Scope for Thalassemia Gene Therapy by Disruption of Aberrant Regulatory Elements

Journal of Clinical MedicineNovember 13, 2019
Petros PatsaliMarina Kleanthous

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