Biophysics of CRISPR

This feed focuses on broad characteristics of the CRISPR system and the proteins associated with it.

February 25, 2021

Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML.

Leukemia
Elizabeth HeyesFlorian Grebien
February 23, 2021
Preprint
Open Access

Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis

BioRxiv : the Preprint Server for Biology
Theresa CaseyK. M. Plaut
February 24, 2021
Open Access

Evidence that a naturally occurring single nucleotide polymorphism in the RagC gene of Leishmania donovani contributes to reduced virulence.

PLoS Neglected Tropical Diseases
Patrick LypaczewskiGreg Matlashewski
February 23, 2021
Review
Open Access

Wheat omics: Classical breeding to new breeding technologies.

Saudi Journal of Biological Sciences
Fahad AlotaibiAbdullah Alrajhi
February 23, 2021
Open Access

Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9.

Molecular Therapy. Methods & Clinical Development
Suvd ByambaaYutaka Hanazono
February 23, 2021
Open Access

Development of a new genetic reference material system based on Saccharomyces cerevisiae cells.

Molecular Therapy. Methods & Clinical Development
Xin HeDaru Lu
February 23, 2021
Open Access

Ubiquitous and Tissue-specific RNA Targeting in Drosophila Melanogaster using CRISPR/CasRx.

Journal of Visualized Experiments : JoVE
Ruichen SunOmar S Akbari
February 23, 2021
Open Access

Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis in zebrafish development.

Cardiovascular Research
Christopher J DerrickEmily S Noël
February 21, 2021
Open Access

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement.

Science Advances
Evan A BoyleWilliam J Greenleaf
February 21, 2021
Open Access

Ex vivo visualization of RNA polymerase III-specific gene activity with electron microscopy.

Communications Biology
Sina MangerAchilleas S Frangakis
February 21, 2021
Review

Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy.

Transgenic Research
Esther K ElliottLyn R Griffiths
February 20, 2021

Potential Application of CRISPR/Cas9 System to Engineer Abiotic Stress Tolerance in Plants.

Protein and Peptide Letters
Temoor AhmedBin Li
February 20, 2021
Review
Open Access

Using CRISPR to enhance T cell effector function for therapeutic applications.

Cytokine: X
Julian J Freen-van Heeren
February 20, 2021

PFKP facilitates Atg4B phosphorylation during amino acid deprivation-induced autophagy.

Cellular Signalling
Xiuzhi LiXianghua Yan
February 19, 2021
Preprint
Open Access

Comparative Study Between the CRISPR/Cpf1 and CRISPR/Cas9 systems for Multiplex Gene Editing in Maize

ResearchSquare
Chongzhi GongWeiwei Qi
February 19, 2021
Open Access

CBRPP: a new RNA-centric method to study RNA-protein interactions.

RNA Biology
Yunfei LiFuping You

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