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Bivalency & Gene Expression (Keystone)

Bivalency & Gene Expression (Keystone) diagram by undefined

Bivalent chromatin are segments of DNA, bound to histone proteins, that have both repressing and activating epigenetic regulators in the same region. Here is the latest research on bivalent chromatin and gene expression.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor

Proceedings of the National Academy of Sciences of the United States of AmericaOctober 16, 2019
Katharine L DiehlTom W Muir
11
27
Biochemical and Biophysical Research Communications

Bmi1 counteracts hematopoietic stem cell aging by repressing target genes and enforcing the stem cell gene signature

Biochemical and Biophysical Research CommunicationsNovember 5, 2019
Eriko NittaAtsushi Iwama
6
2
The Journal of Clinical Investigation

Simplified steps to heterologous prime-boost HIV vaccine development?

The Journal of Clinical InvestigationOctober 1, 2019
Nelson L Michael
5
1
Journal for Immunotherapy of Cancer

Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples

Journal for Immunotherapy of CancerNovember 23, 2019
Eleanor M ScottMargaret R Duffy
11
1
Scientific Reports

ONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression

Scientific ReportsDecember 29, 2019
Qingyang MaXiangyin Kong
4
Cell Death & Disease

Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis

Cell Death & DiseaseFebruary 1, 2020
Jiahuan ChenBing Zhang
2
Critical Reviews in Biochemistry and Molecular Biology

The multiscale effects of polycomb mechanisms on 3D chromatin folding

Critical Reviews in Biochemistry and Molecular BiologyNovember 9, 2019
Thierry Cheutin, Giacomo Cavalli
49
11
Trends in Genetics : TIG

The Bivalent Genome: Characterization, Structure, and Regulation

Trends in Genetics : TIGDecember 11, 2019
Enrique BlancoLuciano Di Croce
76
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer

A Randomized-Controlled Phase 2 Study of the MET Antibody Emibetuzumab in Combination with Erlotinib as First-Line Treatment for EGFR Mutation-Positive NSCLC Patients

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung CancerOctober 18, 2019
Giorgio ScagliottiGee-Chen Chang

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