Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

February 28, 2021

Glutathione: an old and small molecule with great functions and new applications in the brain and in Alzheimer's disease.

Antioxidants & Redox Signaling
Mohamed HaddadCharles Ramassamy
February 28, 2021
Open Access

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus.

Communications Biology
Deidre JanssonMike Dragunow
February 28, 2021

Intranasal drug delivery for treatment of Alzheimer's disease.

Drug Delivery and Translational Research
Leonor C FonsecaPedro Fonte
February 28, 2021

Exploring Therapeutic Advancement and Strategies Associated with Drug Delivery in Brain-Tumor Targeting.

Critical Reviews in Therapeutic Drug Carrier Systems
Bjorn John StephenAbhijeet Singh
February 27, 2021

Permeability of the blood brain barrier after traumatic brain injury: radiological considerations.

Journal of Neurotrauma
Michael AmooGerard F Curley
February 27, 2021

Vascular dysfunction in the brain; implications for heavy metals exposure.

Current Hypertension Reviews
Nzube F OlungOmamuyovwi M Ijomone
February 27, 2021
Open Access

Are CSF CXCL13 concentrations solely dependent on intrathecal production? A commentary on "Chemokine CXCL13 in serum, CSF, and blood-CSF barrier function".

Fluids and Barriers of the CNS
Krista D DiSanoAndrew R Pachner
February 27, 2021
Review
Open Access

Glymphatic System as a Gateway to Connect Neurodegeneration From Periphery to CNS.

Frontiers in Neuroscience
Gianfranco NataleFrancesco Fornai
February 27, 2021
Comment / Editorial

Cellular Trojan horses for delivery of nanomedicines to brain tumors: where do we stand and what is next?

Nanomedicine
Luis Exequiel Ibarra
February 27, 2021
Open Access

Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP-43 pathology.

Clinical and Translational Medicine
Barış GençP Hande Özdinler
February 27, 2021

miR-219 overexpressing oligodendrocyte progenitor cells for treating compression spinal cord injury.

Metabolic Brain Disease
Bahareh NazariJafar Ai
February 27, 2021
Review

Methods used for the measurement of blood-brain barrier integrity.

Metabolic Brain Disease
Huixin SunChaohui Duan
February 27, 2021

Cortisol promotes breast-to-brain metastasis through the blood-cerebrospinal fluid barrier.

Cancer Reports
Robert A HerreraJosh Neman
February 27, 2021

Potential impact of Helicobacter pylori-related metabolic syndrome and Galectin-3 on liver, chronic kidney and brain disorders.

Metabolism: Clinical and Experimental
Marina BozikiJannis Kountouras
February 27, 2021
Review

White Matter Lesions in Migraine.

The American Journal of Pathology
Katharina Eikermann-Haerter, Susie Y Huang
February 27, 2021
Review

Lentiviral mediated gene delivery as an effective therapeutic approach for Parkinson disease.

Neuroscience Letters
Violina KakotyRajeev Taliyan

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