Blood Brain Barrier Regulation in Health & Disease

The blood brain barrier is essential in regulating the movement of molecules and substances in and out of the brain. Disruption to the blood brain barrier and changes in permeability allow pathogens and inflammatory molecules to cross the barrier and may play a part in the pathogenesis of neurodegenerative disorders. Here is the latest research in this field.

April 18, 2021
Review

Bioengineered microfluidic blood-brain barrier models in oncology research.

Translational Oncology
Robin AugustineAnwarul Hasan
April 16, 2021

Measuring barrier function in organ-on-chips with cleanroom-free integration of multiplexable electrodes.

Lab on a Chip
Elsbeth G B M BossinkLoes I Segerink
April 16, 2021

High altitude cerebral edema - its own entity or end-stage acute mountain sickness?

Journal of Applied Physiology
Rachel E F TurnerJustin Stevan Lawley
April 16, 2021
Open Access

Examination of a blood-brain barrier targeting β-galactosidase-monoclonal antibody fusion protein in a murine model of GM1-gangliosidosis.

Molecular Genetics and Metabolism Reports
Michael J PrzybillaChester B Whitley
April 15, 2021

Dietary spermidine improves cognitive function.

Cell Reports
Sabrina SchroederFrank Madeo
April 15, 2021
Open Access

Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers.

PloS One
Leah A Marquez-CurtisJanet A W Elliott
April 15, 2021

Exercise alleviates symptoms of CNS lupus.

Brain Research
Alexander JacobJessy Alexander
April 14, 2021
Review

Nanoparticles approaches in neurodegenerative diseases diagnosis and treatment.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Zahra AsefyZaker Ceferov
April 14, 2021

An engineered neurovascular unit for modeling neuroinflammation.

Biofabrication
Suyeong SeoHong Nam Kim
April 13, 2021

Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Yue ShuWeitian Lu
April 12, 2021
Preprint
Open Access

Isolation of sensory hair cell specific exosomes in human perilymph

BioRxiv : the Preprint Server for Biology
Z. PeiHinrich Staecker
April 12, 2021

miR-24 targets HMOX1 to regulate inflammation and neurofunction in rats with cerebral vasospasm after subarachnoid hemorrhage.

American Journal of Translational Research
Xiaodong DengQi Zhang
April 12, 2021
Review
Open Access

Glial Cell-Based Vascular Mechanisms and Transplantation Therapies in Brain Vessel and Neurodegenerative Diseases.

Frontiers in Cellular Neuroscience
Yingying ZhaoZheng Zachory Wei

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