Blood-Brain Barrier Transport in Neurodegeneration

The Blood-Brain Barrier (BBB) is essential in regulating the movement of biomolecules in and out of the brain. For example, membrane transporters in the BBB can be important for regulating drug movement in the brain and dysregulation of these processes may play a role in neurodegenerative disorders. Discover the latest research on BBB transporters here.

July 11, 2020

Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Petra SušjanIva Hafner-Bratkovič
July 27, 2020

Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye

Advances in Experimental Medicine and Biology
Bernice H Wong, David L Silver
July 16, 2020
Review
Open Access

Brain delivery of antidotes by polymeric nanoparticles

Journal of Applied Toxicology : JAT
Eniko Manek, Georg A Petroianu
July 21, 2020
Open Access

Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury

Mediators of Inflammation
Duraisamy KempurajAsgar Zaheer
July 27, 2020
Open Access

The impact of acute rosiglitazone on insulin pharmacokinetics at the blood-brain barrier

Endocrinology, Diabetes & Metabolism
Demi C GalindoElizabeth M Rhea
July 29, 2020
Review
Open Access

Insights into the Effects of Mesenchymal Stem Cell-Derived Secretome in Parkinson's Disease

International Journal of Molecular Sciences
Michele d'AngeloVanessa Castelli
July 31, 2020
Review
Open Access

The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics

Acta Neuropathologica
Sarah A KentClaire S Durrant
August 3, 2020

The impact of neurovascular, blood-brain barrier, and glymphatic dysfunction in neurodegenerative and metabolic diseases

International Review of Neurobiology
Molly Braun, Jeffrey J Iliff
August 1, 2020
Review

Carbon nanostructures: the drug and the delivery system for brain disorders

International Journal of Pharmaceutics
T K HennaK Pramod
July 30, 2020
Review

Opportunities for Histone Deacetylase Inhibition in Amyotrophic Lateral Sclerosis

British Journal of Pharmacology
Yvonne E KlinglLudo Van Den Bosch
July 16, 2020
Review
Open Access

Severe acute respiratory syndrome coronavirus-2 may be an underappreciated pathogen of the central nervous system

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
S B AlamJagdeep K Sandhu
July 28, 2020

Anthropogenic Iron Oxide Nanoparticles Induce Damage to Brain Microvascular Endothelial Cells Forming the Blood-Brain Barrier

Journal of Alzheimer's Disease : JAD
Lorena Gárate-VélezJosé Luis Rodríguez-López
July 30, 2020
Open Access

Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07

Journal of Cachexia, Sarcopenia and Muscle
Yongjun HuDavid E Smith
July 29, 2020

Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid

Frontiers in Molecular Neuroscience
Simona Federica SpampinatoMaria Angela Sortino
July 30, 2020
Review

The Role of Neurovascular System in Neurodegenerative Diseases

Molecular Neurobiology
Ajmal AhmadMohammad Moshahid Khan
July 15, 2020

In Vitro self-organized three-dimensional model of the blood-brain barrier microvasculature

Biomedical Materials
Agathe FigarolMichiya Matsusaki

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