Blood-Brain Barrier Transport in Neurodegeneration

The blood brain barrier is important for regulating the movement of biomolecules in and out of the brain. For example, membrane transporters in the blood brain barrier can be essential for regulating drug movement and dysregulation of these processes may play a role in neurodegeneration. This feed follows the latest research on this topic.

January 9, 2022
Review

Engineered human blood-brain barrier microfluidic model for vascular permeability analyses.

Nature Protocols
Cynthia HajalRoger D Kamm
January 8, 2022

The skeletal muscle relaxer cyclobenzaprine is a potent non-competitive antagonist of histamine H1 receptors.

The Journal of Pharmacology and Experimental Therapeutics
Kirti SinghNader H Moniri
January 3, 2022
Open Access

The Bradykinin B2 Receptor Agonist (NG291) Causes Rapid Onset of Transient Blood-Brain Barrier Disruption Without Evidence of Early Brain Injury.

Frontiers in Neuroscience
Sergio R Rodríguez-MassóAntonio Henrique Martins
December 25, 2021

Drug Delivery Systems and Strategies to Overcome the Barriers of Brain.

Current Pharmaceutical Design
Yogesh GargAmit Bhatia
December 24, 2021
Review
Open Access

Delivery of Toxins and Effectors by Bacterial Membrane Vesicles.

Toxins
Adrian MacionRenata Godlewska
December 12, 2021

A Compartmental Model for the Iron Trafficking Across the Blood-Brain Barriers in Neurodegenerative Diseases.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society
E FiciaraC Guiot
December 11, 2021
Review
Open Access

Recent Advances in Biological Activity, New Formulations and Prodrugs of Ferulic Acid.

International Journal of Molecular Sciences
Monika Stompor-Gorący, Maciej Machaczka
December 8, 2021
Review

Breaking barriers: Neurodegenerative repercussions of radiotherapy induced damage on the blood-brain and blood-tumor barrier.

Free Radical Biology & Medicine
Barrett D Allen, Charles L Limoli
November 29, 2021
Review
Open Access

Proteome of the Luminal Surface of the Blood-Brain Barrier.

Proteomes
Jennifer J HillDanica B Stanimirovic
November 26, 2021
Open Access

Comprehensive Mapping of the Cell Response to Borrelia bavariensis in the Brain Microvascular Endothelial Cells in vitro Using RNA-Seq.

Frontiers in Microbiology
Zuzana TkáčováMangesh Bhide
November 14, 2021
Review

Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Mariafrancesca ScaliseCesare Indiveri
November 12, 2021
Review

Potential of different cells-derived exosomal microRNA cargos for treating spinal cord injury.

Journal of Orthopaedic Translation
Dayu PanShiqing Feng
October 22, 2021

Sustained A1 Adenosine Receptor Antagonist Drug Release from Nanoparticles Functionalized by a Neural Tracing Protein.

ACS Chemical Neuroscience
Md Musfizur HassanGuangzhao Mao
October 23, 2021

The antimetastatic breast cancer activity of the viral protein-derived peptide vCPP2319 as revealed by cellular biomechanics.

The FEBS Journal
Filipa D OliveiraMiguel A R B Castanho

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