Blood-Brain Barrier Transport in Neurodegeneration

The blood brain barrier is important for regulating the movement of biomolecules in and out of the brain. For example, membrane transporters in the blood brain barrier can be essential for regulating drug movement and dysregulation of these processes may play a role in neurodegeneration. This feed follows the latest research on this topic.

November 5, 2020
Open Access

Functional Investigation of Solute Carrier Family 35, Member F2, in Three Cellular Models of the Primate Blood-Brain Barrier

Drug Metabolism and Disposition : the Biological Fate of Chemicals
Tatsuki MochizukiHiroyuki Kusuhara
November 27, 2020
Open Access

Blood-brain barrier transport using a high affinity, brain-selective VNAR antibody targeting transferrin receptor 1

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Pawel StockiJ Lynn Rutkowski
December 29, 2020

Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB)

Handbook of Experimental Pharmacology
Hans Christian Cederberg HelmsBirger Brodin
January 7, 2021

High glucose-induced effects on Na+ -K+ -Cl- cotransport and Na+ /H+ exchange of blood-brain barrier endothelial cells: involvement of SGK1, PKCβII and SPAK/OSR1

American Journal of Physiology. Cell Physiology
Nicholas R KlugMartha E O'Donnell
January 9, 2021
Open Access

Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro

Fluids and Barriers of the CNS
Snehal RautAbraham Al-Ahmad
January 23, 2021
Open Access

Improved Safety and Anti-Glioblastoma Efficacy of CAT3-Encapsulated SMEDDS through Metabolism Modification.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Hongliang WangYuling Liu
January 12, 2021
Review
Open Access

Blood-Brain Barrier Damage in Ischemic Stroke and Its Regulation by Endothelial Mechanotransduction

Frontiers in Physiology
Keqing NianEno E Ebong
December 20, 2020

3D Self-Organized Human Blood-Brain Barrier in a Microfluidic Chip

Methods in Molecular Biology
Marco CampisiRoger Dale Kamm
December 10, 2020
Open Access

Oxidative Stress, Folate Receptor Autoimmunity, and CSF Findings in Severe Infantile Autism

Autism Research and Treatment
Vincent T RamaekersEdward V Quadros
December 8, 2020

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

Journal of Visualized Experiments : JoVE
Sovannarath PongRakesh Karmacharya
December 5, 2020
Open Access

P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury

Neurotrauma Reports
Sydney M VitaBernadette E Grayson
November 22, 2020

Comparison of micron- and nano-particle transport in the human nasal cavity with a focus on the olfactory region

Computers in Biology and Medicine
Shantanu Vachhani, Clement Kleinstreuer
January 19, 2021

Recent advances on drug delivery nanocarriers for cerebral disorders

Biomedical Materials
Zheng ZhouChen Jiang
January 23, 2021

Dual Channel Microfluidics for Mimicking the Blood-Brain Barrier.

ACS Nano
Boris BuchroithnerJaroslaw Jacak
November 12, 2020
Review
Open Access

Constitutive Androstane Receptor: A Peripheral and a Neurovascular Stress or Environmental Sensor

Cells
Fabiana OlivieroLaila Mselli-Lakhal
January 12, 2021
Open Access

Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial Cells

Tissue Barriers
Guinever Eustaquio Do ImperioStephen G Matthews

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