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Brain Aging

Brain Aging diagram by Santibhavank P, Shutterstock
Santibhavank P, Shutterstock

Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.

Top 20 most recent papers
Acta Neuropathologica

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

Acta NeuropathologicaJanuary 20, 2020
Sven J van der LeeHenne Holstege
6
Annals of Neurology

Imaging Biomarkers of Alzheimer's Disease in Multiple Sclerosis

Annals of NeurologyJanuary 24, 2020
Burcu ZeydanKejal Kantarci
Neurology

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

NeurologyJanuary 23, 2020
Eider M Arenaza-UrquijoPrashanthi Vemuri
Frontiers in Aging Neuroscience

Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods

Frontiers in Aging NeuroscienceJanuary 24, 2020
David J ClarkRachael D Seidler
Trends in Molecular Medicine

Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

Trends in Molecular MedicineJanuary 22, 2020
Benjamin C ReevesKristopher T Kahle
9
Neuropathology and Applied Neurobiology

Brain mural cell loss in the parietal cortex in alzheimer's disease correlates with cognitive decline and TDP-43 pathology

Neuropathology and Applied NeurobiologyJanuary 24, 2020
Philippe BourassaFrédéric Calon
NeuroImage

Striatal iron content is linked to reduced fronto-striatal brain function under working memory load

NeuroImageJanuary 24, 2020
Karen M RodrigueKristen M Kennedy
bioRxiv

Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

bioRxivJanuary 19, 2020
Simon R CoxElliot M Tucker-Drob
5
Frontiers in Genetics

Aberrantly High Levels of Somatic LINE-1 Expression and Retrotransposition in Human Neurological Disorders

Frontiers in GeneticsJanuary 24, 2020
Diane M Terry, Scott E Devine
Neurobiology of Learning and Memory

Rolipram treatment during consolidation ameliorates long-term object location memory in aged male mice

Neurobiology of Learning and MemoryJanuary 22, 2020
Mathieu E WimmerTed Abel
1
bioRxiv

Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

bioRxivJanuary 21, 2020
Chrysia Maria PegasiouMariana Vargas-Caballero
bioRxiv

Neural differentiation is moderated by age in scene- but not face-selective cortical regions

bioRxivJanuary 23, 2020
Sabina SrokovaMichael D Rugg
Neuroscience

The differential effect of treadmill exercise intensity on hippocampal soluble aβ and lipid metabolism in APP/PS1 mice

NeuroscienceJanuary 20, 2020
B ZengH L Liu
2
Journal of Mass Spectrometry : JMS

Orbitrap mass spectrometry for monitoring the ganglioside pattern in human cerebellum development and aging

Journal of Mass Spectrometry : JMSJanuary 22, 2020
Raluca IcaAlina D Zamfir
Neural Regeneration Research

Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging

Neural Regeneration ResearchJanuary 22, 2020
Jie ZhangYi Wang
1
Frontiers in Aging Neuroscience

Mitochondrial Degeneration and Autophagy Associated With Delayed Effects of Radiation in the Mouse Brain

Frontiers in Aging NeuroscienceJanuary 21, 2020
Neel K SharmaSanchita P Ghosh
6
DNA and Cell Biology

Aerobic Endurance Exercise Ameliorates Renal Vascular Sclerosis in Aged Mice by Regulating PI3K/AKT/mTOR Signaling Pathway

DNA and Cell BiologyJanuary 24, 2020
Chuncha BaoBin Shu
Journal of Aging and Physical Activity

An Intense, But Ecologically Valid, Resistance Exercise Session Does Not Alter Growth Factors Associated With Cognitive Health

Journal of Aging and Physical ActivityJanuary 23, 2020
Kieran J MarstonJeremiah J Peiffer
bioRxiv

Cerebellar and Prefrontal-Cortical Engagement During Higher-Order Rule Learning in Older Adulthood

bioRxivJanuary 23, 2020
T. Bryan JacksonJessica A Bernard
Advances in Clinical Chemistry

Myokines: The endocrine coupling of skeletal muscle and bone

Advances in Clinical ChemistryJanuary 19, 2020
Marta GomarascaGiovanni Lombardi
8
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