Brain Organoids in Disease Modeling

Brain organoids are used to represent an in vitro model of the human brain. These brain organoids are derived from three-dimensional human pluripotent stem cells and can be used to help study brain biology, early brain development and different brain diseases. Discover the latest research on brain organoids in disease modeling here.

August 4, 2020
Open Access

In vitro induction and in vivo engraftment of kidney organoids derived from human pluripotent stem cells

Experimental and Therapeutic Medicine
Denglu ZhangShengtian Zhao
July 6, 2020
Review
Open Access

Genetic pathways involved in human speech disorders

Current Opinion in Genetics & Development
Joery den Hoed, Simon E Fisher
July 17, 2020
Open Access

Brainstem Organoids From Human Pluripotent Stem Cells

Frontiers in Neuroscience
Nobuyuki EuraEiichiro Mori
July 14, 2020
Review

PsychENCODE and beyond: transcriptomics and epigenomics of brain development and organoids

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Alexandre JourdonFlora M Vaccarino
July 31, 2020
Review

Current concepts in tumour-derived organoids

British Journal of Cancer
Ross J PorterMairi H McLean
July 10, 2020

3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo

Annual Review of Neuroscience
Silvia VelascoPaola Arlotta
July 28, 2020
Preprint

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

BioRxiv : the Preprint Server for Biology
Fadi JacobG.-l. Ming
July 28, 2020
Open Access

Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types

Translational Vision Science & Technology
Phuong T LamMichael L Robinson
July 29, 2020
Open Access

Convolutional Neural Networks Can Predict Retinal Differentiation in Retinal Organoids

Frontiers in Cellular Neuroscience
Evgenii KegelesPetr Baranov
July 21, 2020

Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
Li QinDaniel J Müller
July 30, 2020
Open Access

Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential

Cell Reports
Shin-Ichi MaeKenji Osafune
August 4, 2020
Review

Cerebral organoids to unravel the mechanisms underlying malformations of human cortical development

Seminars in Cell & Developmental Biology
Olivia KrefftJulia Ladewig
July 4, 2020
Preprint
Open Access

An early cell shape transition drives evolutionary expansion of the human forebrain

BioRxiv : the Preprint Server for Biology
S. Benito-KwiecinskiM. A. Lancaster
July 5, 2020
Preprint
Open Access

A model of traumatic brain injury using human iPSC-derived cortical brain organoids

BioRxiv : the Preprint Server for Biology
J. D. LaiJustin Ichida
July 28, 2020

In vitro models for ASD-patient-derived iPSCs and cerebral organoids

Progress in Molecular Biology and Translational Science
Sonja Simone HohmannTanja Maria Michel
July 23, 2020
Preprint
Open Access

The supramolecular landscape of growing human axons

BioRxiv : the Preprint Server for Biology
P. C. HoffmannM. A. Lancaster
July 17, 2020
Review
Open Access

Application of Fused Organoid Models to Study Human Brain Development and Neural Disorders

Frontiers in Cellular Neuroscience
Augustin ChenShan Bian
July 31, 2020
Open Access

Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

Nature Communications
Maria-Patapia ZafeiriouWolfram-Hubertus Zimmermann

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