Brain Organoids in Disease Modeling

Brain organoids are three-dimensional cell culture models derived from human pluripotent stem cells. Since they resemble the embryonic brain, they can be used to help study brain biology, early brain development, and brain diseases. Discover the latest research on brain organoids in disease modeling here.

January 16, 2022

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.

Cell Stem Cell
Jitske JansenRafael Kramann
January 15, 2022

PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids.

Stem Cell Reports
Nobuhiko ShirakiKohji Nishida
January 13, 2022

[Adrenal glands stem cells: general signaling pathways].

Problemy e̊ndokrinologii
O V GlazovaP Y Volchkov
January 12, 2022
Open Access

In Vitro and In Vivo Models to Study Nephropathic Cystinosis.

Pang Yuk CheungJennifer A Hollywood
January 12, 2022
Open Access

Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids.

Ilkka FagerlundTarja Malm
January 12, 2022
Open Access

Controllable Fabrication of Composite Core-Shell Capsules at a Macroscale as Organoid Biocarriers.

ACS Applied Bio Materials
Fan HeJianhua Qin
January 12, 2022

Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids.

ACS Applied Bio Materials
Camille Cassel de CampsChristopher Moraes
January 12, 2022

Hypes and Hopes of Stem Cell Therapies in Dentistry: a Review.

Stem Cell Reviews and Reports
Alessandra Rodriguez Y BaenaManuela Monti
January 11, 2022

Controlling Morphology and Functions of Cardiac Organoids by Two-Dimensional Geometrical Templates.

Cells, Tissues, Organs
Plansky HoangZhen Ma
January 9, 2022

FASN-dependent de novo lipogenesis is required for brain development.

Proceedings of the National Academy of Sciences of the United States of America
Daniel Gonzalez-BohorquezSebastian Jessberger
January 8, 2022

Engineering brain assembloids to interrogate human neural circuits.

Nature Protocols
Yuki MiuraSergiu P Pașca
January 6, 2022

ID2 controls differentiation of enteroendocrine cells in mouse small intestine.

Acta Physiologica
Valeriya V ZininaNatalia Soshnikova
January 6, 2022

Challenges of Organoid Research.

Annual Review of Neuroscience
Madeline G Andrews, Arnold R Kriegstein
January 5, 2022

Intermittent compressive force induces cell cycling and reduces apoptosis in embryoid bodies of mouse induced pluripotent stem cells.

International Journal of Oral Science
Jeeranan ManokawinchokeThanaphum Osathanon
January 5, 2022

Modeling human neurodevelopmental diseases with brain organoids.

Cell Regeneration
Xiaoxiang LuYangfei Xiang
January 4, 2022
Open Access

Generation of Vascularized Brain Organoids to Study Neurovascular Interactions

BioRxiv : the Preprint Server for Biology
Zhen-Ge LuoY. Chen

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