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Breast Cancer: BRCA1 & BRCA2

Breast Cancer: BRCA1 & BRCA2 diagram by ibreakstock, Shutterstock
ibreakstock, Shutterstock

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

Top 20 most recent papers
May 14, 2020
Open Access

Alternative mRNA splicing can attenuate the pathogenicity of presumed loss-of-function variants in BRCA2

Genetics in Medicine : Official Journal of the American College of Medical Genetics
Romy L S MesmanMaaike P G Vreeswijk
May 18, 2020

AGA Clinical Practice Update on Pancreas Cancer Screening in High Risk Individuals: Expert Review

Harry R AslanianMarcia Irene Canto
May 21, 2020
ReviewOpen Access

Replication Fork Remodeling and Therapy Escape in DNA Damage Response-Deficient Cancers

Frontiers in Oncology
Martin LiptaySven Rottenberg
May 19, 2020

Germline Loss-of-function Variants in MBD4 are Rare in Finnish Patients with Uveal Melanoma

Pigment Cell & Melanoma Research
Pauliina RepoJoni A Turunen
May 15, 2020

Quinacrine based gold hybrid nanoparticle caused apoptosis through modulating replication fork in oral cancer stem cells

Molecular Pharmaceutics
Krushna Chandra HembramChanakya Nath Kundu
May 20, 2020

Poly(ADP-ribose) polymerase inhibitors in prostate and urothelial cancer

Current Opinion in Urology
Stephan BrönimannMelanie R Hassler
May 16, 2020

Clinicopathological analysis of early-stage breast cancer patients that meet indications for BRCA1/2 genetic testing

Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu
Hongyu XiangLing Xu
May 19, 2020
Open Access

Disassembly of the Shieldin Complex by TRIP13

Cell Cycle
Prabha SarangiAlan D D'Andrea
May 23, 2020

Diagnosing hereditary cancer predisposition in men with prostate cancer

Genetics in Medicine : Official Journal of the American College of Medical Genetics
Mary PritzlaffBrian T Helfand
May 19, 2020
ReviewOpen Access

Fertility preservation in patients with BRCA mutation

Suleiman GhunaimHatem A Azim
May 20, 2020
Open Access

Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination

Nature Communications
Jessica L KelliherJustin W C Leung
May 24, 2020

High-throughput functional evaluation of BRCA2 variants of unknown significance

Nature Communications
Masachika IkegamiHiroyuki Mano
May 15, 2020

Cortical network dysfunction revealed by magnetoencephalography in carriers of spinocerebellar ataxia 1 or 2 mutation

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Elisa VisaniLaura Canafoglia
May 15, 2020
PreprintOpen Access

Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats

L. LindenburgFlorian Hollfelder

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