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Breast Cancer: BRCA1 & BRCA2

Breast Cancer: BRCA1 & BRCA2 diagram by ibreakstock, Shutterstock
ibreakstock, Shutterstock

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

Top 20 most recent papers
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

TBCRC 031: Randomized Phase II Study of Neoadjuvant Cisplatin Versus Doxorubicin-Cyclophosphamide in Germline BRCA Carriers With HER2-Negative Breast Cancer (the INFORM trial)

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyFebruary 26, 2020
Nadine TungJudy E Garber
23
Nature Reviews. Molecular Cell Biology

The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication

Nature Reviews. Molecular Cell BiologyFebruary 26, 2020
Madalena Tarsounas, Patrick Sung
21
Science Translational Medicine

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Science Translational MedicineFebruary 21, 2020
Florence CoussyElisabetta Marangoni
16
1
BioMed Research International

Development and Validation of a 34-Gene Inherited Cancer Predisposition Panel Using Next-Generation Sequencing

BioMed Research InternationalFebruary 25, 2020
Sun Hee RosenthalRenius Owen
1
The International Journal of Biochemistry & Cell Biology

Downregulation of METTL14 increases apoptosis and autophagy induced by cisplatin in pancreatic cancer cells

The International Journal of Biochemistry & Cell BiologyFebruary 26, 2020
Fanhua KongLeping Yang
1

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