Cadherins and Catenins

Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other. Catenins are a family of proteins found in complexes with cadherin cell adhesion molecules of animal cells: alpha-catenin can bind to β-catenin and can also bind actin. β-catenin binds the cytoplasmic domain of some cadherins. Discover the latest research on cadherins and catenins here.

January 19, 2022

Whole-genome and Transcriptome Sequencing Identified NOTCH2 and HES1 as Potential Markers of Response to Imatinib in Desmoid Tumor (Aggressive Fibromatosis): A Phase II Trial Study.

Cancer Research and Treatment : Official Journal of Korean Cancer Association
Joonha KwonHyo Song Kim
January 19, 2022

Epithelial-Mesenchymal Transition-Inducing Factors Involved in the Progression of Lung Cancers.

Biomolecules & Therapeutics
Min-Woo NamKyung-Chul Choi
January 19, 2022

2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.

International Journal of Molecular Medicine
Jana KotulovaPetr Dzubak
January 19, 2022

Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.

The Journal of Pathology
Daisuke YamamotoMasanobu Oshima
January 18, 2022

Effects of Palmitic Acid on localization of embryo cell fate and blastocyst formation gene products.

Reproduction : the Official Journal of the Society for the Study of Fertility
Michele D CalderAndrew J Watson
January 18, 2022

Canonical thyroid hormone receptor β action stimulates hepatocyte proliferation in male mice.

Georg Sebastian HönesLars Christian Moeller
January 18, 2022

[Mechanism of ring finger protein 11 regulating Akt signaling pathway to promote osteogenic differentiation of bone marrow mesenchymal stem cells].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Wen DengYing Du
January 17, 2022
Open Access

The oncogene FOXQ1 is a selective activator of Wnt/β-catenin signalling

BioRxiv : the Preprint Server for Biology
G. PizzolatoStefan Koch
January 17, 2022
Open Access

An efficient simplified method for the generation of corneal epithelial cells from human pluripotent stem cells

BioRxiv : the Preprint Server for Biology
Rodi Abdalkader, K.-i. Kamei
January 17, 2022

Sclerostin protects against vascular calcification development in mice.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Annelies De MaréAnja Verhulst
January 17, 2022

Whole-Exome Sequencing Reveals Novel NDP Variants in X-Linked Familial Exudative Vitreoretinopathy.

European Journal of Ophthalmology
Yujiao PengMu Yang

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Adherens Junctions

An adherens junction is defined as a cell junction whose cytoplasmic face is linked to the actin cytoskeleton. They can appear as bands encircling the cell (zonula adherens) or as spots of attachment to the extracellular matrix (adhesion plaques). Adherens junctions uniquely disassemble in uterine epithelial cells to allow the blastocyst to penetrate between epithelial cells. Discover the latest research on adherens junctions here.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Basement Membranes

Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Cancer Cell Invasion: Nanomedicine

Nanomedicine is a promising alternative for cancer detection and therapy that utilizes nanoparticles, such as liposomes. Nanoparticles can potentially target cancer cell invasion and metastasis. Discover the latest research on Cancer Cell Invasion: Nanomedicine here.

Cell Adhesion Molecules in AS

Cell adhesion molecules expressed on the vascular endothelium and circulating leukocytes in response to inflammatory stimuli are implicated in atherosclerosis. Here is the latest research.

Cell Adhesion Molecules in the Brain

Cell adhesion molecules found on cell surface help cells bind with other cells or the extracellular matrix to maintain structure and function. Here is the latest research on their role in the brain.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.


Chondrogenesis is the earliest phase of skeletal development, involving mesenchymal cell recruitment and migration, condensation of progenitors, and chondrocyte differentiation, and maturation and resulting in the formation of cartilage and bone during endochondral ossification. Here is the latest research.

Cytoskeleton Dynamics in Cell Motility

Cell motility depend directly on the regulated dynamics of the cytoskeleton. Here is the latest research focusing on cytoskeleton dynamics in various different modes of motility including flagellar, gliding, and twitching motility.

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