Cancer Epigenetics

Epigenetic changes are present and dysregulated in many cancers, including DNA methylation, non-coding RNA segments and post-translational protein modifications. The epigenetic changes may or may not provide advantages for the cancer cells. Here is the latest research on cancer epigenetics.

December 7, 2021

DNA hydroxymethylation in high-grade gliomas.

Journal of Neurological Surgery. Part A, Central European Neurosurgery
Angelika Stapińska-SyniecMichał Sobstyl
December 7, 2021

DNA methylation variation along the cancer epigenome and the identification of novel epigenetic driver events.

Nucleic Acids Research
Richard Heery, Martin H Schaefer
December 6, 2021
Review
Open Access

Biliary Tract Cancers: Treatment Updates and Future Directions in the Era of Precision Medicine and Immuno-Oncology.

Frontiers in Oncology
Ashish ManneArjun Mittra
December 4, 2021
Review

Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma.

Progress in Retinal and Eye Research
Peiwei ChaiXianqun Fan
December 4, 2021

Epigenetic condensates regulate chromatin activity and tumorigenesis.

Molecular & Cellular Oncology
Bi ShiHao Jiang
December 4, 2021
Open Access

Comprehensive Pan-Cancer Analysis of the Prognostic and Immunological Roles of the METTL3/lncRNA-SNHG1/miRNA-140-3p/UBE2C Axis.

Frontiers in Cell and Developmental Biology
Xiulin JiangLincan Duan
December 4, 2021

Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma.

Journal of Experimental & Clinical Cancer Research : CR
Cinzia LanziGiuliana Cassinelli
December 3, 2021

The ups and downs of DNA methylation: an interview with Gerd Pfeifer.

Epigenomics
Gerd P Pfeifer
December 3, 2021

A DNA adductome analysis revealed a reduction in the global level of C5-hydroxymethyl-2'-deoxycytidine in the non-tumoral upper urinary tract mucosa of urothelial carcinoma patients.

Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society
Yuto MatsushitaHaruhiko Sugimura
December 2, 2021

Synergistic alterations in the multilevel chromatin structure anchor dysregulated genes in small cell lung cancer.

Computational and Structural Biotechnology Journal
Dan GuoZhiyong Liang
December 2, 2021

Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats.

Toxicological Sciences : an Official Journal of the Society of Toxicology
Robin MesnageMichael N Antoniou
December 2, 2021

Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma.

Genes & Genomics
Su Chan Park, Ji Min Lee

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