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Cancer Genomics (Preprints)

Cancer Genomics (Preprints)   diagram by Feixiong Cheng et al
Feixiong Cheng et al

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

Top 20 most recent papers
bioRxiv

Frequent extrachromosomal oncogene amplification drives aggressive tumors

bioRxivNovember 28, 2019
Hoon KimRoel G.W. Verhaak
81
bioRxiv

Ultra-low input single tube linked-read library method enables short-read NGS systems to generate highly accurate and economical long-range sequencing information for de novo genome assembly and haplotype phasing

bioRxivNovember 29, 2019
Zhoutao ChenMing Lei
48
bioRxiv

Multi-site clonality analyses uncovers pervasive subclonal heterogeneity and branching evolution across melanoma metastases

bioRxivNovember 27, 2019
Roy RabbieDavid James Adams
31
bioRxiv

ACTOR: a latent Dirichlet model to compare expressed isoform proportions to a reference panel

bioRxivNovember 26, 2019
Sean D. McCabeMichael I. Love
34
bioRxiv

MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen

bioRxivNovember 27, 2019
Hannah WeberMichael J. Garabedian
5
bioRxiv

Learning mutational signatures and their multidimensional genomic properties with TensorSignatures

bioRxivNovember 21, 2019
Harald Vöhringer, Moritz Gerstung
75
bioRxiv

ATAC-seq identifies thousands of extrachromosomal circular DNA in cancers and cell lines

bioRxivNovember 16, 2019
Pankaj KumarAnindya Dutta
20
bioRxiv

Single-cell tumor phylogeny inference with copy-number constrained mutation losses

bioRxivNovember 26, 2019
Gryte SatasBenjamin J. Raphael
47
bioRxiv

Mechanistic models of signaling pathways deconvolute the functional landscape of glioblastoma at single cell resolution

bioRxivNovember 29, 2019
Matias M FalcoJoaquin Dopazo
3
bioRxiv

XenoCP: Cloud-based BAM cleansing tool for RNA and DNA from Xenograft

bioRxivNovember 15, 2019
Sasi Arunachalam, Jing-Hui Zhang
7
bioRxiv

Cancer Predisposition Sequencing Reporter (CPSR): a flexible variant report engine for germline screening in cancer

bioRxivNovember 22, 2019
Sigve NakkenEivind Hovig
12
bioRxiv

TopicNet: a framework for measuring transcriptional regulatory network change

bioRxivDecember 2, 2019
Shao Ke LouMark B. Gerstein
20
bioRxiv

Single-cell RNA-seq data reveals TNBC tumor heterogeneity through characterizing subclone compositions and proportions

bioRxivNovember 28, 2019
Wei-Da WangYun Xiao
16
bioRxiv

Intra-Species Differences in Population Size shape Life History and Genome Evolution

bioRxivNovember 23, 2019
David WillemsenDario Riccardo Valenzano
42
bioRxiv

An integrative resource for investigating genetic model of drug response in cancer

bioRxivNovember 15, 2019
Yi Guo, Xiang Chen
8
bioRxiv

Robust foreground detection in somatic copy number data

bioRxivNovember 20, 2019
Aditya S DeshpandeMarcin B Imielinski
30
bioRxiv

Discovery Of The First Human Retro-Giant Virus: Description of its morphology, retroviral kinase and ability to induce tumours in mice

bioRxivNovember 22, 2019
Elena Angela Lusi, Federico Caicci
13
bioRxiv

SEQUENCING CHEMICALLY INDUCED MUTATIONS IN THE MUTAMOUSE LACZ REPORTER GENE IDENTIFIES HUMAN CANCER MUTATIONAL SIGNATURES

bioRxivNovember 29, 2019
Marc A BealFrancesco Marchetti
4
bioRxiv

Integrative genomic and epigenomic analyses identify a distinct role of c-Myc and L-Myc for lineage determination in small cell lung cancer

bioRxivNovember 29, 2019
Ayushi H PatelHideo Watanabe
9
bioRxiv

Reference-free deconvolution of complex DNA methylation data – a detailed protocol

bioRxivNovember 24, 2019
Michael R SchererPavlo Lutsik
32

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