Cancer Genomics (Preprints)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

September 6, 2020
Preprint
Open Access

TSC-Insensitive Rheb Mutations Induce Oncogenic Transformation Through a Combination of Hyperactive mTORC1 Signalling and Metabolic Reprogramming

BioRxiv : the Preprint Server for Biology
Christopher G ProudT. J. Sargeant
September 12, 2020
Preprint
Open Access

Integration of Biodynamic Imaging and RNA-seq predicts chemotherapy response in canine diffuse large B-cell lymphoma

BioRxiv : the Preprint Server for Biology
J. FineNadia Atallah Lanman
September 4, 2020
Preprint
Open Access

PPM1D is a neuroblastoma oncogene and therapeutic target in childhood neural tumors.

BioRxiv : the Preprint Server for Biology
Jelena MilosevicP. Kogner
September 10, 2020
Preprint
Open Access

Pervasive duplication of tumor suppressors in Afrotherians during the evolution of large bodies and reduced cancer risk

BioRxiv : the Preprint Server for Biology
J. M. Vazquez, Vincent J Lynch
September 5, 2020
Preprint
Open Access

Mutational landscapes of normal breast during age and pregnancy determine cancer risk

BioRxiv : the Preprint Server for Biology
Biancastella CereserJ. Stebbing
September 9, 2020
Preprint
Open Access

Chromatin accessibility analysis uncovers regulatory element landscape in prostate cancer progression

BioRxiv : the Preprint Server for Biology
J. Uusi-MäkeläMatti Nykter
September 2, 2020
Preprint
Open Access

Inhibition of HIF-1α accumulation in prostate cancer cells is initiated during early stages of mammalian orthoreovirus infection

BioRxiv : the Preprint Server for Biology
L. D. Bussiere, Cathy L. Miller
September 18, 2020
Preprint

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma

MedRxiv : the Preprint Server for Health Sciences
R. J. NellPieter A Van der Velden
September 8, 2020
Preprint

Performances of targeted RNA-sequencing for the analysis of fusion transcripts, gene mutation and expression in haematological malignancies.

BioRxiv : the Preprint Server for Biology
S. HayettePierre Sujobert
August 28, 2020
Preprint
Open Access

Prostate Epithelial Genes Define Docetaxel-Sensitive Prostate Cancer Molecular Subtype

BioRxiv : the Preprint Server for Biology
H. HanYoung Deuk Choi
August 29, 2020
Preprint
Open Access

Snord67 promotes lymph node metastasis and regulates U6-mediated alternative splicing in breast cancer

BioRxiv : the Preprint Server for Biology
Y. L. ChaoChad V Pecot
September 18, 2020
Preprint

USP28 and SPINT2 mediate cell cycle arrest after whole genome doubling

BioRxiv : the Preprint Server for Biology
Zuzana StorchovaF. Buchholz
August 27, 2020
Preprint
Open Access

Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum

BioRxiv : the Preprint Server for Biology
P. ChakrabortyMohit Kumar Jolly
August 25, 2020
Preprint
Open Access

Bacterial single-cell genomics enables phylogenetic analysis of in vitro evolutionary studies

BioRxiv : the Preprint Server for Biology
M. BawnIain C Macaulay
September 18, 2020
Preprint

Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance

BioRxiv : the Preprint Server for Biology
V. BelyaevaDaria Siekhaus
August 25, 2020
Preprint
Open Access

An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers

BioRxiv : the Preprint Server for Biology
K. ChatsirisupachaiJoao Pedro de Magalhaes
August 28, 2020
Preprint
Open Access

Ontogeny and Vulnerabilities of Lapatinib Drug-Tolerant Persisters in HER2+ Breast Cancer

BioRxiv : the Preprint Server for Biology
Benjamin G. NeelA. Tsirigos
September 8, 2020
Preprint
Open Access

TAZ-CAMTA1 and YAP-TFE3 modulate the basal TAZ/YAP transcriptional program by recruiting the ATAC histone acetyltransferase complex

BioRxiv : the Preprint Server for Biology
N. MerrittMunir R Tanas
September 8, 2020
Preprint
Open Access

Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function

BioRxiv : the Preprint Server for Biology
R. WiesheuSeth B Coffelt
September 9, 2020
Preprint
Open Access

Tumors widely express hundreds of embryonic germline genes

BioRxiv : the Preprint Server for Biology
J. W. BruggemanGeert Hamer

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