Feed Preview

Fast Growing

CAR-T cells

CAR-T cells diagram by Meletios Verras, Shutterstock
Meletios Verras, Shutterstock

Chimeric antigen receptor (CAR) T cells are cells that are genetically engineered to recognize and target specific proteins. The ability of these cells to recognize cancer antigens and eliminate tumor cells have transformed cancer immunotherapy approaches. Here is the latest research on CAR-T cells.

Top 20 most recent papers
Nature Genetics

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Nature GeneticsFebruary 19, 2020
Maria Gutierrez-ArcelusSoumya Raychaudhuri
Bone Marrow Transplantation

The EBMT activity survey on hematopoietic-cell transplantation and cellular therapy 2018: CAR-T's come into focus

Bone Marrow TransplantationFebruary 19, 2020
Jakob R PasswegEuropean Society for Blood and Marrow Transplantation (EBMT)
International Immunopharmacology

Interleukin-2 as immunotherapeutic in the autoimmune diseases

International ImmunopharmacologyFebruary 15, 2020
Alexy Orozco ValenciaMarco Antonio Stephano
Molecular Therapy. Methods & Clinical Development

A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells

Molecular Therapy. Methods & Clinical DevelopmentFebruary 22, 2020
Darin BloembergScott McComb
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation

Acute Kidney Injury after CAR-T Cell Therapy: Low Incidence and Rapid Recovery

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow TransplantationFebruary 24, 2020
Victoria GutgartsInsara Jaffer Sathick
Cancer Cell

Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells

Cancer CellFebruary 13, 2020
Irene Scarfò, Marcela V Maus

Harnessing T Cells to Target Pediatric Acute Myeloid Leukemia: CARs, BiTEs, and Beyond

ChildrenFebruary 22, 2020
Rebecca EpperlyMireya Paulina Velasquez
Antiviral Research

Adoptive T-cell therapy for HBV-associated HCC and HBV infection

Antiviral ResearchFebruary 23, 2020
Anthony T Tan, Sophia Schreiber

Acoustogenetic Control of CAR T Cells via Focused Ultrasound

bioRxivFebruary 19, 2020
YIQIAN WUYingxiao Wang
Frontiers in Oncology

Controlling Cytokine Release Syndrome to Harness the Full Potential of CAR-Based Cellular Therapy

Frontiers in OncologyFebruary 21, 2020
Monica S ThakarSubramaniam Malarkannan
Frontiers in Oncology

Adoptive Cell Therapy: A Novel and Potential Immunotherapy for Glioblastoma

Frontiers in OncologyFebruary 22, 2020
Jingyu WangJue Hu
The Journal of Clinical Investigation

Single residue in CD28-costimulated CAR T cells limits long-term persistence and antitumor durability

The Journal of Clinical InvestigationFebruary 19, 2020
Sonia GuedanAvery D Posey

See more papers from this feed

Related Feeds

Angiogenesis Inhibitors to Treat Cancer

Cancer treatments including angiogenesis inhibitors prevent tumor cells from receiving nutrients and oxygen. Here is the latest research on angiogenesis inhibitors for the treatment of cancer.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Biosensors for Cancer Detection

Biosensors are devices that are designed to detect a specific biological analyte by essentially converting a biological entity (ie, protein, DNA, RNA) into an electrical signal that can be detected and analyzed. The use of biosensors in cancer detection and monitoring holds vast potential. Biosensors can be designed to detect emerging cancer biomarkers and to determine drug effectiveness at various target sites. Biosensor technology has the potential to provide fast and accurate detection, reliable imaging of cancer cells, and monitoring of angiogenesis and cancer metastasis, and the ability to determine the effectiveness of anticancer chemotherapy agents.

Breast Cancer: Chemo-Resistance

Some cancers are difficult to treat and aggressive including the "triple-negative" breast cancer. This type of cancer is chemoresistant even before chemotherapy begins. Here are the latest discoveries chemo-resistance in breast cancer.

Cancer Cell Invasion: Nanomedicine

Nanomedicine is a promising alternative for cancer detection and therapy that utilizes nanoparticles, such as liposomes. Nanoparticles can potentially target cancer cell invasion and metastasis. Discover the latest research on Cancer Cell Invasion: Nanomedicine here.

Cancer Disparities

Cancer disparities refers to differences in cancer outcomes (e.g., number of cancer cases, related health complications) across population groups.

Cancer Genomics

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research here.

Cancer Immunotherapy

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest research on cancer immunotherapy here.

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.

Cancer Metabolic Reprogramming

Cancer metabolic reprogramming is important for the rapid growth and proliferation of cancer cells. Cancer cells have the ability to change their metabolic demands depending on their environment, regulated by the activation of oncogenes or loss of tumor suppressor genes. Here is the latest research on cancer metabolic reprogramming.

© 2020 Meta ULC. All rights reserved