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CAR-T cells

CAR-T cells diagram by Meletios Verras, Shutterstock
Meletios Verras, Shutterstock

Chimeric antigen receptor (CAR) T cells are cells that are genetically engineered to recognize and target specific proteins. The ability of these cells to recognize cancer antigens and eliminate tumor cells have transformed cancer immunotherapy approaches. Here is the latest research on CAR-T cells.

Top 20 most recent papers
Nature Genetics

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Nature GeneticsFebruary 19, 2020
Maria Gutierrez-ArcelusSoumya Raychaudhuri
33
Bone Marrow Transplantation

The EBMT activity survey on hematopoietic-cell transplantation and cellular therapy 2018: CAR-T's come into focus

Bone Marrow TransplantationFebruary 19, 2020
Jakob R PasswegEuropean Society for Blood and Marrow Transplantation (EBMT)
28
International Immunopharmacology

Interleukin-2 as immunotherapeutic in the autoimmune diseases

International ImmunopharmacologyFebruary 15, 2020
Alexy Orozco ValenciaMarco Antonio Stephano
Molecular Therapy. Methods & Clinical Development

A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells

Molecular Therapy. Methods & Clinical DevelopmentFebruary 22, 2020
Darin BloembergScott McComb
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation

Acute Kidney Injury after CAR-T Cell Therapy: Low Incidence and Rapid Recovery

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow TransplantationFebruary 24, 2020
Victoria GutgartsInsara Jaffer Sathick
Cancer Cell

Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells

Cancer CellFebruary 13, 2020
Irene Scarfò, Marcela V Maus
13
Children

Harnessing T Cells to Target Pediatric Acute Myeloid Leukemia: CARs, BiTEs, and Beyond

ChildrenFebruary 22, 2020
Rebecca EpperlyMireya Paulina Velasquez
2
Antiviral Research

Adoptive T-cell therapy for HBV-associated HCC and HBV infection

Antiviral ResearchFebruary 23, 2020
Anthony T Tan, Sophia Schreiber
bioRxiv

Acoustogenetic Control of CAR T Cells via Focused Ultrasound

bioRxivFebruary 19, 2020
YIQIAN WUYingxiao Wang
4
Frontiers in Oncology

Controlling Cytokine Release Syndrome to Harness the Full Potential of CAR-Based Cellular Therapy

Frontiers in OncologyFebruary 21, 2020
Monica S ThakarSubramaniam Malarkannan
1
Frontiers in Oncology

Adoptive Cell Therapy: A Novel and Potential Immunotherapy for Glioblastoma

Frontiers in OncologyFebruary 22, 2020
Jingyu WangJue Hu
1
The Journal of Clinical Investigation

Single residue in CD28-costimulated CAR T cells limits long-term persistence and antitumor durability

The Journal of Clinical InvestigationFebruary 19, 2020
Sonia GuedanAvery D Posey
43

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