Cardiovascular Biology of GLP-1

Glucagon-like peptide 1 (GLP-1) plays a role in glucose metabolism, energy homeostasis, and inflammation suppression. GLP-1 receptor signaling has been shown to impact cardiovascular function. This feed focuses on the role of GLP-1 and GLP-1 receptor agonists on cardiovascular biology.

August 3, 2020

Long-acting GLP-1 receptor agonists: Findings and implications of cardiovascular outcomes trials

JAAPA : Official Journal of the American Academy of Physician Assistants
Scott Urquhart, Stephen Willis
July 31, 2020

Pharmacokinetics, pharmacodynamics, and tolerability of JY09 in healthy Chinese subjects: A titrating, dose-escalating study


International Journal of Clinical Pharmacology and Therapeutics
Guangyu YangJuan Li
July 30, 2020

Fighting diabetes mellitus: Pharmacological and non-pharmacological approaches

Current Pharmaceutical Design
Xin WangHelong Quan
August 4, 2020
Review

An overview of glucagon-like peptide-1 receptor agonists for the treatment of metabolic syndrome: A drug repositioning

Iranian Journal of Basic Medical Sciences
Maryam RameshradHossein Hosseinzadeh
July 29, 2020
Open Access

The GPR40 full agonist SCO-267 improves liver parameters in a mouse model of nonalcoholic fatty liver disease without affecting glucose or body weight

The Journal of Pharmacology and Experimental Therapeutics
Mitsugi OokawaraYusuke Moritoh
July 30, 2020
Review
Open Access

A Review on Semaglutide: An Oral Glucagon-Like Peptide 1 Receptor Agonist in Management of Type 2 Diabetes Mellitus

Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders
Sanjay Kalra, Rakesh Sahay
July 30, 2020
Open Access

Glucagon-like peptide-1 receptor mediates the beneficial effect of Liraglutide in an acute lung injury mouse model involving the thioredoxin interacting protein

American Journal of Physiology. Endocrinology and Metabolism
Wenyong ZhouTianru Jin
August 5, 2020

Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects

Nature Chemical Biology
Snehal N ChaudhariA Sloan Devlin

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