Cardiovascular Disease & TET2

Cardiovascular diseases are the number one cause of deaths globally. Tet methylcytosine dioxygenase 2 (TET2)-mediated hematopoiesis has been implicated in accelerating heart failure. Here is the latest research on cardiovascular diseases and TET2.

August 28, 2020
Open Access

Human TET2 bridges cancer and immunity

Qian Zhang, Jean-Laurent Casanova
August 4, 2020

Clonal Hematopoiesis: Mechanisms Driving Dominance of Stem Cell Clones

Grant Challen, Margaret A Goodell
July 1, 2020
Open Access

TET2 deficiency reprograms the germinal center B cell epigenome and silences genes linked to lymphomagenesis

Science Advances
Wojciech RosikiewiczSheng Li
August 19, 2020
Open Access

Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective

Nature Neuroscience
Lee L MarshallViviane Labrie
July 6, 2020

Progress on epigenetic regulation of iron homeostasis

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Lingyan DuanFudi Wang
July 30, 2020

HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML

Feiteng HuangLing Li
August 21, 2020

Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability

Science Signaling
Suhas S KharatShyam K Sharan
July 7, 2020
Open Access

Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver

Toxicology and Applied Pharmacology
Yi WenJoseph Irudayaraj
July 24, 2020
Open Access

Mutational spectrum and prognosis in NRAS-mutated acute myeloid leukemia

Scientific Reports
Shujuan WangYanfang Liu
July 5, 2020
Open Access

Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques

BioRxiv : the Preprint Server for Biology
Aisha A AlJanahiC. E. Dunbar
August 23, 2020
Open Access

Clonal Hematopoiesis of Indeterminate Potential: A Multidisciplinary Challenge in Personalized Hematology

Journal of Personalized Medicine
Gregor HoermannPeter Valent
August 21, 2020

TET2 expedites coronary heart disease by promoting microRNA-126 expression and inhibiting the E2F3/PI3K/AKT axis

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
Yan Xu
September 3, 2020
Open Access

Effect of Perfluorooctanoic Acid on the Epigenetic and Tight Junction Genes of the Mouse Intestine

Faizan RashidJoseph Maria Kumar Irudayaraj
August 28, 2020

Cytologic features of blastic plasmacytoid dendritic cell neoplasm involving liver: A case report and literature review

Diagnostic Cytopathology
Yanna DingKathryn Lindsey
August 12, 2020

A Personalized Prediction Model for Outcomes after Allogeneic Hematopoietic Cell Transplant in Myelodysplastic Syndromes Patients

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation
Aziz NazhaWael Saber
July 4, 2020
Open Access

Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions

Cell Systems
Leanna MorinishiSteven J Altschuler

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