CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

May 24, 2020
Open Access

Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells

Proceedings of the National Academy of Sciences of the United States of America
M Zeeshan ChaudhryLuka Cicin-Sain
April 23, 2020

CD70 Activation Decreases Pulmonary Fibroblast Production of Extracellular Matrix Proteins.

American Journal of Respiratory Cell and Molecular Biology
Thi K Tran-NguyenSteven R Duncan
January 29, 2020
Open Access

Protein kinase 2 (CK2) controls CD4+ T cell effector function in the pathogenesis of colitis

Mucosal Immunology
Wei YangEtty N Benveniste
March 6, 2020

Antileishmanial Drugs Modulate IL-12 Expression and Inflammasome Activation in Primary Human Cells

The Journal of Immunology : Official Journal of the American Association of Immunologists
Sonia AndréJérôme Estaquier
August 11, 2020
Case Report
Open Access

X-Linked Lymphoproliferative Disease in Latvia: A Report of Two Clinically Distinct Cases

Case Reports in Medicine
Ieva NokalnaLinda Gailite
May 1, 2020

Transcriptional regulation of Treg homeostasis and functional specification

Cellular and Molecular Life Sciences : CMLS
Ke Wang, Wenxian Fu
April 29, 2020
Open Access

Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma

Journal of Neuro-oncology
Dominic MaggioZhengping Zhuang
June 18, 2020
Case Report
Open Access

Recurrent, Severe Aphthous Stomatitis and Mucosal Ulcers as Primary Manifestations of a Novel STAT1 Gain-of-Function Mutation

Frontiers in Immunology
Melinda ErdősLászló Maródi
July 22, 2020
Open Access

The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection.

Nature Immunology
Abdenour AbbasElena Tomasello
January 6, 2021
Open Access

The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus

Nature Communications
Mohammad M KarimiMatthias Merkenschlager
February 13, 2020
Open Access

Tuning T helper cell differentiation by ITK

Biochemical Society Transactions
Jessica P ElmoreAvery August
February 26, 2020
Open Access

Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

Proceedings of the National Academy of Sciences of the United States of America
Heidi J ElsaesserDavid G Brooks
April 18, 2020
Open Access

In response to complement anaphylatoxin peptides C3a and C5a, human vascular endothelial cells migrate and mediate the activation of B-cells and polarization of T-cells.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Pooja ShivshankarRick A Wetsel

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