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Cell Atlas of the human Thymus: Development & Aging

Cell Atlas of the human Thymus: Development & Aging diagram by photss, Shutterstock
photss, Shutterstock

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human thymus gland at the single cell level will help build a single cell atlas of this gland, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the thymus gland during development and aging. Discover the latest research on the cell atlas of the human thymus here.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 18, 2019
Jacob S HengJeremy Nathans
6
Proceedings of the National Academy of Sciences of the United States of America

Determinants governing T cell receptor α/β-chain pairing in repertoire formation of identical twins

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 28, 2019
Hidetaka TannoJörg J Goronzy
17
Immunity & Ageing : I & a

Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging

Immunity & Ageing : I & aJanuary 29, 2020
Rachel ThomasDong-Ming Su
6
1
1
bioRxiv

Interruption of thymic activity in adults improves responses to tumor immunotherapy

bioRxivJanuary 9, 2020
José Almeida-SantosJocelyne Demengeot
10
Rejuvenation Research

Commentary on Some Recent Theses Relevant to Combating Aging: December 2019

Rejuvenation ResearchNovember 21, 2019
Benjamin Zealley, Aubrey D N J de Grey
1
bioRxiv

A cell atlas of human thymic development defines T cell repertoire formation

bioRxivJanuary 28, 2020
Jong-Eun ParkSarah A Teichmann
147
The Journal of Allergy and Clinical Immunology

Recurrent microdeletions at chromosome 2p11.2 are associated with thymic hypoplasia and features resembling DiGeorge Syndrome

The Journal of Allergy and Clinical ImmunologyOctober 11, 2019
Joshua D BernstockT Prescott Atkinson
1
4
Open Forum Infectious Diseases

Thymus Imaging Detection and Size Is Inversely Associated With Metabolic Syndrome and Frailty in People With HIV

Open Forum Infectious DiseasesOctober 30, 2019
Giovanni GuaraldiCristina Mussini
2
7
1
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Vascular Remodeling Induced by Biological Stresses

Yakugaku zasshi : Journal of the Pharmaceutical Society of JapanApril 3, 2020
Hiroshi Hasegawa
Science

A cell atlas of human thymic development defines T cell repertoire formation

ScienceFebruary 22, 2020
Jong-Eun ParkSarah A Teichmann
371
11
2
1
Cell Reports

Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

Cell ReportsNovember 28, 2019
Izumi OhigashiYousuke Takahama
11
International Immunology

Physiology and pathology of T-cell aging

International ImmunologyJanuary 23, 2020
Nagahiro MinatoYoko Hamazaki
1
1
1
Laboratory animal research

Characterization of aged male BALB/ccenp mice as a model of dementia

Laboratory animal researchMarch 25, 2020
Nashelly EsquivelClaudio Rodríguez
1

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