Lipids are essential in many biological functions, including membrane structure, energy storage, and cell signaling. Find the latest research on the cell biology of lipids here.
Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.
Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.
Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.
Clinical lipidology focuses on diagnosis, pathophysiology, and clinical management of lipid and lipoprotein disorders. Here is the latest research.
Dynamin GTPases are proteins that are responsible for endocytosis in cells, as well as division of organelles, cytokinesis, and pathogen resistance. Discover the latest research on dynamin GTPases here.
Several protein complexes are present on the ER membrane that facilitates the protein translocation across and into the ER where folding can occur. Discover the latest research on ER Membrane: Protein Translocation here.
Adsorptive and receptor-mediated endocytosis via clathrin-coated vesicles provides the major and best-characterized portal for uptake of multiple molecules and particles into cells. Via clathrin-dependent endocytosis, cells receive nutrients, regulate receptors and other plasma membrane constituents, take up antigens, and remove senescent, excess, and potentially harmful substances from the extracellular fluid. Discover the latest research on endocytic system here.
Dynamin GTPases are proteins that are responsible for endocytosis in cells, as well as division of organelles, cytokinesis, and pathogen resistance. Discover the latest research on dynamin GTPases here.
Extracellular vesicles are cell-derived structures containing complex cargo, including proteins and nucleic acids, that originate from endosomal systems or the plasma membrane. Here is the latest research on technologies for the analysis of extracellular vesicles.
Extracellular vesicles are implicated in propagating toxic amyloid proteins in neurodegenerative disorders. Here is the latest research on extracellular vesicles including exosomes in the CNS.