Cell Signaling by Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Discover the latest research on cell signaling and RTK here.

September 15, 2020
Open Access

Isatuximab Acts Through Fc-Dependent, Independent, and Direct Pathways to Kill Multiple Myeloma Cells

Frontiers in Immunology
Chen ZhuMarielle Chiron
September 7, 2020
Review
Open Access

Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network

Annals of Oncology : Official Journal of the European Society for Medical Oncology
G D DemetriJ-Y Blay
September 3, 2020
Review
Open Access

Recent advances in the management of gastrointestinal stromal tumor

World Journal of Clinical Cases
Monjur Ahmed
September 12, 2020
Open Access

Immunohistochemistry as a screening tool for NTRK gene fusions: results of a first Belgian ring trial

Virchows Archiv : an International Journal of Pathology
Koen De WinneKaren Zwaenepoel
September 19, 2020
Open Access

N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells

Oncology Reports
Amelia G PérezJulio Cesar M De-Freitas-Junior
September 20, 2020

BDNF activates postsynaptic TrkB receptors to induce endocannabinoid release and inhibit presynaptic calcium influx at a calyx-type synapse

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Yichen WuLei Xue
September 2, 2020
Open Access

AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations

Cell Communication and Signaling : CCS
Yameng SiHongbing Jiang
September 6, 2020

BDNF and nicotine dependence: associations and potential mechanisms

Reviews in the Neurosciences
Zeyi HuangSijie Tan
September 9, 2020
Review

The root cause of drug resistance in HER2-positive breast cancer and the therapeutic approaches to overcoming the resistance

Pharmacology & Therapeutics
Yuesheng Zhang
September 3, 2020
Review
Open Access

STAT3, the Challenge for Chemotherapeutic and Radiotherapeutic Efficacy

Cancers
Ping-Lian YangLi-Yan Xu
September 17, 2020

Positive Association of Human SHC3 Gene with Schizophrenia in a Northeast Chinese Han Population

Psychiatry Investigation
Ye LvZhi-Lin Luan
September 11, 2020

Targeted Modulation of FAK/PI3K/PDK1/AKT and FAK/p53 Pathways by Cucurbitacin B for the Antiproliferation Effect Against Human Cholangiocarcinoma Cells

The American Journal of Chinese Medicine
Sirinapha KlungsaengLaddawan Senggunprai
September 20, 2020

Design, synthesis and biological evaluation of novel heptamethine cyanine dye-erlotinib conjugates as antitumor agents

Bioorganic & Medicinal Chemistry Letters
Xiaoguang YangChun Guo
September 11, 2020
Open Access

RASAL1 and ROS1 Gene Variants in Hereditary Breast Cancer

Cancers
Federica IsidoriElena Bonora
September 16, 2020
Open Access

Association of cytokines levels with epidermal growth factor receptor mutation in lung cancer patients

Journal of Cancer Research and Therapeutics
Priyanka GaurSarika Pandey
September 9, 2020

Bacterial expression of 183-227aa region of HER3 extracellular domain I and preparation and identification of its polyclonal antibodies

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Lei ZhuLiang Yan

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