Cell-Type-Specific Viral Vectors (ASM)

Viral vectors are used in biological research and therapy to deliver genetic material into cells. However, the efficiency of viral vectors varies depending on the cell type. Here is the latest research on cell-type-specific viral vectors.

January 12, 2021
Open Access

Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity

Molecular Therapy. Methods & Clinical Development
James M TerminiRonald C Desrosiers
January 6, 2021

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

Nature Medicine
Ruiping WangLinghua Wang
January 8, 2021
Open Access

Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering

Nucleic Acids Research
Kassidy J TompkinsWendy R Gordon
January 6, 2021

Optogenetic Manipulation of the Vagus Nerve

Advances in Experimental Medicine and Biology
Toya Okonogi, Takuya Sasaki
January 8, 2021
Preprint
Open Access

Therapeutic adenine base editing corrects nonsense mutation and improves visual function in a mouse model of Leber congenital amaurosis

BioRxiv : the Preprint Server for Biology
D. H. JoJeong Hun Kim
January 15, 2021
Preprint
Open Access

Parallel functional testing identifies enhancers active in early postnatal mouse brain

BioRxiv : the Preprint Server for Biology
J. T. LambertAlex S Nord
January 14, 2021
Preprint
Open Access

CERTL reduces C16 ceramide, amyloid-β levels and inflammation in a model of Alzheimer's disease

ResearchSquare
Simone Mwenda CrivelliPilar Martinez-Martinez
January 7, 2021
Open Access

Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice

International Journal of Molecular Sciences
Nguyen Khanh ToanSang-Gun Ahn
January 15, 2021
Open Access

The protective effects of fibroblast growth factor 10 against hepatic ischemia-reperfusion injury in mice

Redox Biology
Santie LiWeitao Cong
January 8, 2021

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice

Nature
Luke W KoblanDavid R Liu
January 13, 2021
Preprint
Open Access

Apolipoprotein M attenuates doxorubicin cardiotoxicity by regulating transcription factor EB

BioRxiv : the Preprint Server for Biology
Z. GuoAli Javaheri
January 16, 2021
Review
Open Access

Update on Gene Therapy Clinical Trials for Choroideremia and Potential Experimental Therapies

Medicina
Alessandro AbboudaEnzo Maria Vingolo
January 8, 2021

Molecular determinants and heterogeneity underlying host response to EV-A71 infection at single-cell resolution

RNA Biology
Rei-Lin KuoBertrand Chin-Ming Tan
January 13, 2021

A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

Proceedings of the National Academy of Sciences of the United States of America
Ryoichi TashimaMakoto Tsuda

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Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthrax Vaccines (ASM)

Three different types of anthrax vaccines are available; a live-attenuated, an alum-precipitated cell-free filtrate and a protein recombinant vaccine. The effectiveness between the three is uncertain, but the live-attenuated have shown to reduce the risk of anthrax with low adverse events. Here is the latest research on anthrax vaccines.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Ascariasis (ASM)

Ascariasis is a helminthic infection of global distribution with more than 1.4 billion persons infected throughout the world. Here is the latest research.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

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