Cell-Type-Specific Viral Vectors

Viral vectors are used in biological research and therapy to deliver genetic material into cells. However, the efficiency of viral vectors varies depending on the cell type. Here is the latest research on cell-type-specific viral vectors.

July 30, 2020
Review
Open Access

Development of New Strategies Using Extracellular Vesicles Loaded with Exogenous Nucleic Acid

Pharmaceutics
Nicola Salvatore Orefice
July 31, 2020
Open Access

The changing mouse embryo transcriptome at whole tissue and single-cell resolution

Nature
Peng HeBarbara J Wold
July 23, 2020
Preprint
Open Access

Ventral Tegmental Area GABA, glutamate, and glutamate-GABA neurons are heterogenous in their electrophysiological and pharmacological properties

BioRxiv : the Preprint Server for Biology
J. A. Miranda-BarrientosMarisela Morales
July 30, 2020

Broad Antibody and Cellular Immune Response from a Phase 2 Clinical Trial with a Novel Multivalent Poxvirus Based RSV Vaccine

The Journal of Infectious Diseases
Elke JordanPaul Chaplin
July 29, 2020
Open Access

Targeting Catecholaminergic Systems in Transgenic Rats With a CAV-2 Vector Harboring a Cre-Dependent DREADD Cassette

Frontiers in Molecular Neuroscience
Juan-Carlos CerpaEtienne Coutureau
July 23, 2020
Open Access

Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment

Investigative Ophthalmology & Visual Science
Xiaomeng LiXiaodong Sun
July 30, 2020
Open Access

Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice

Journal of Cellular and Molecular Medicine
Fang QiuWenfeng Chu
August 3, 2020

Retrograde gene transfer into neural pathways mediated by adeno-associated virus (AAV)-AAV receptor interaction

Journal of Neuroscience Methods
Hiromi SanoAtsushi Nambu
July 21, 2020
Open Access

Basal-like and classical cells coexist in pancreatic cancer revealed by single-cell analysis on biopsy-derived pancreatic cancer organoids from the classical subtype

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Natalia JuizNelson Dusetti
July 18, 2020
Review
Open Access

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

International Journal of Molecular Sciences
Laurel C ChandlerKanmin Xue
July 24, 2020
Open Access

Different lineage contexts direct common pro-neural factors to specify distinct retinal cell subtypes

The Journal of Cell Biology
Mei WangJie He
July 21, 2020

Loss of SPEG Inhibitory Phosphorylation of RyR2 Promotes Atrial Fibrillation

Circulation
Hannah M CampbellXander H T Wehrens
July 18, 2020

Viral Delivery of Non-Mutated Human Truncated Tau to Neurons Recapitulates Key Features of Human Tauopathy in Wild-Type Mice

Journal of Alzheimer's Disease : JAD
Thomas VogelsTomáš Hromádka
August 1, 2020

XIAP Protects Retinal Ganglion Cells in the Mutant ND4 Mouse Model of Leber Hereditary Optic Neuropathy

Investigative Ophthalmology & Visual Science
Sarah J WassmerCatherine Tsilfidis
July 31, 2020

AAV-Mediated Combination Gene Therapy for Neuropathic Pain: GAD65, GDNF, and IL-10

Molecular Therapy. Methods & Clinical Development
Daewook KimSujeong Kim
July 23, 2020
Review

Gene therapy: a double-edged sword with great powers

Molecular and Cellular Biochemistry
Ran Tang, Zhigang Xu

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