Centromeres & Kinetochores

The centromere is a specialized DNA sequence of a chromosome that links a pair of sister chromatids. During prophase, specialized regions of the centromeres known as kinetochores attach chromosomes to spindle fibers. Here is the latest research on centromeres and the kinetochore.

September 17, 2021

CTLA-4 polymorphisms in Thai patients with rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.

International Journal of Rheumatic Diseases
Worawit LouthrenooFujio Takeuchi
September 17, 2021

Regulation of mitotic chromosome architecture and resolution of ultrafine anaphase bridges by PICH.

Cell Cycle
Primrose Chanboonyasitt, Ying Wai Chan
September 16, 2021
Open Access

Helical metaphase chromatid coiling is conserved

BioRxiv : the Preprint Server for Biology
I. KubalovaVeit Schubert
September 16, 2021
Open Access

The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages.

BMC Molecular and Cell Biology
Florence MompartMartine Yerle-Bouissou
September 15, 2021
Open Access

Ancestral chromosomes for the Peronosporaceae inferred from a telomere-to-telomere genome assembly of Peronospora effusa.

BioRxiv : the Preprint Server for Biology
K. FletcherRichard Michelmore
September 15, 2021

LINC01123 potentially correlates with radioresistance in glioma through the miR-151a/CENPB axis.

Neuropathology : Official Journal of the Japanese Society of Neuropathology
Weicheng TianTao Sun
September 14, 2021

Soma-to-germline transformation in chromatin-linked neurodevelopmental disorders?

The FEBS Journal
Katherine M Bonefas, Shigeki Iwase
September 14, 2021

Live-cell imaging reveals square shape spindles and long mitosis duration in the silkworm holocentric cells.

MicroPublication. Biology
Lucien VanpoperinghePhong T Tran
September 14, 2021
Open Access

Genome-wide activation screens to increase adeno-associated virus production.

Molecular Therapy. Nucleic Acids
Christopher R BarnesDavid V Schaffer
September 13, 2021

A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.

Bioorganic Chemistry
Ayad A Al-HamashiL M Viranga Tillekeratne
September 12, 2021
Open Access

Kre28-Spc105 interaction is essential for their recruitment at the kinetochore

BioRxiv : the Preprint Server for Biology
Babhrubahan RoyA. P. Joglekar
September 12, 2021
Open Access

MKLP2 functions in early mitosis to ensure proper chromosome congression

BioRxiv : the Preprint Server for Biology
M. S. SchrockMatthew K. Summers
September 11, 2021

The RAD51 recombinase protects mitotic chromatin in human cells.

Nature Communications
Isabel E WassingFumiko Esashi
September 10, 2021
Open Access

KIF2C promotes the proliferation of hepatocellular carcinoma cells in vitro and in vivo.

Experimental and Therapeutic Medicine
Zhenya GaoBaoyu Li
September 10, 2021
Open Access

First Description of a Satellite DNA in Manatees' Centromeric Regions.

Frontiers in Genetics
Mirela Pelizaro ValeriMarta Svartman
September 10, 2021

Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release.

Genes & Development
Ryotaro KawasumiDana Branzei

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