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CfDNA Sequencing

CfDNA Sequencing diagram by Rashedul Islam Rony, Wikimedia
Rashedul Islam Rony, Wikimedia

Circulating free DNA (cfDNA) are degraded DNA fragments released to the blood plasma. cfDNA has been shown to be a useful biomarker for a multitude of ailments other than cancer and fetal medicine. Here is the latest research on Circulating free DNA (cfDNA) sequencing.

Top 20 most recent papers
bioRxiv

Longitudinal whole-exome sequencing of cell-free DNA unravels the metastatic evolutionary dynamics of BRCA2 mutated breast cancer

bioRxivJanuary 10, 2020
Robert K HastingsJacqueline A Shaw
15
PloS One

Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability

PloS OneJanuary 14, 2020
Paula E NorthAoy Tomita-Mitchell
2
1
BioMed Research International

Circulating Tumour Cells, Circulating Tumour DNA and Circulating Tumour miRNA in Blood Assays in the Different Steps of Colorectal Cancer Management, a Review of the Evidence in 2019

BioMed Research InternationalJanuary 14, 2020
Niki ChristouMuriel Mathonnet
1
bioRxiv

Estimating the rate of cell type degeneration from epigenetic sequencing of cell-free DNA

bioRxivJanuary 16, 2020
Christa CaggianoNoah Zaitlen
Genetics in Medicine : Official Journal of the American College of Medical Genetics

Assessment of laboratories offering cell-free (cf) DNA screening for Down syndrome: results of the 2018 College of American Pathology External Educational Exercises

Genetics in Medicine : Official Journal of the American College of Medical GeneticsJanuary 14, 2020
Glenn E PalomakiJohn A Thorson
1
Bioinformatics

ABEMUS: platform specific and data informed detection of somatic SNVs in cfDNA

BioinformaticsJanuary 11, 2020
Nicola CasiraghiAlessandro Romanel
29
The Breast : Official Journal of the European Society of Mastology

Longitudinal HER2 amplification tracked in circulating tumor DNA for therapeutic effect monitoring and prognostic evaluation in patients with breast cancer

The Breast : Official Journal of the European Society of MastologyJanuary 14, 2020
Xiuwen GuanFei Ma
2
Genome Medicine

Molecular profiling for precision cancer therapies

Genome MedicineJanuary 16, 2020
Eoghan R MaloneLillian L Siu
16
ACS Applied Materials & Interfaces

Dynamically Monitoring the Clonal Evolution of Lung Cancer Based on the Molecular Characterization of Circulating Tumor Cells using Aptamer Cocktail-Modified Nanosubstrates

ACS Applied Materials & InterfacesJanuary 16, 2020
Ying ZhuZunfu Ke
3
Molecular Diagnosis & Therapy

Liquid Biopsy Applications in the Clinic

Molecular Diagnosis & TherapyJanuary 11, 2020
Dake ChenJian Chen
2
Clinica Chimica Acta; International Journal of Clinical Chemistry

Emerging biomarkers in Multiple Myeloma: A Review

Clinica Chimica Acta; International Journal of Clinical ChemistryJanuary 7, 2020
Nidhi GuptaAlpana Sharma
2
Frontiers in Physiology

Salivary Biomarkers for Oral Squamous Cell Carcinoma Diagnosis and Follow-Up: Current Status and Perspectives

Frontiers in PhysiologyJanuary 11, 2020
Marta CristaldiVera Panzarella
1
Clinical and Translational Medicine

Detection of bladder cancer using urinary cell-free DNA and cellular DNA

Clinical and Translational MedicineJanuary 16, 2020
Zhenyu OuZhuo Song
1
Cancers

Molecular Complexity of Diffuse Large B-Cell Lymphoma: Can It Be a Roadmap for Precision Medicine?

CancersJanuary 17, 2020
Nicoletta CoccaroFrancesco Albano
Cancer Investigation

Evaluation of a liquid biopsy protocol using ultra-deep massive parallel sequencing for detecting and quantifying circulation tumor DNA in colorectal cancer patients

Cancer InvestigationJanuary 16, 2020
Huu Thinh NguyenHoai-Nghia Nguyen
2
Nano Convergence

Direct electrophoretic microRNA preparation from clinical samples using nanofilter membrane

Nano ConvergenceJanuary 14, 2020
Kidan LeeKi-Bum Kim
Gynecologic Oncology

Outcomes in women with biopsy-confirmed cervical intraepithelial neoplasia grade 1 or normal cervix and related cofactors: A 15-year population-based cohort study from China

Gynecologic OncologyJanuary 16, 2020
Shang-Ying HuFang-Hui Zhao
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology

Cell-free mitochondrial DNA increases in maternal circulation during healthy pregnancy: a prospective, longitudinal study

American Journal of Physiology. Regulatory, Integrative and Comparative PhysiologyJanuary 9, 2020
Spencer C CushenStyliani Goulopoulou
2
OncoTargets and Therapy

Circulating Cell-Free DNA or Circulating Tumor DNA in the Management of Ovarian and Endometrial Cancer

OncoTargets and TherapyJanuary 11, 2020
Qian ChenJing-He Lang
American Journal of Translational Research

Principles of digital PCR and its applications in current obstetrical and gynecological diseases

American Journal of Translational ResearchJanuary 15, 2020
Xiaodong MaoKangsheng Liu

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