CFTR Mutant Structural Therapy

Over 1700 different mutations in the CFTR genes have been shown to cause cystic fibrosis. Here is the latest research on structural therapy for CFTR mutants.

December 17, 2020
Review

Environmental risks of Pseudomonas aeruginosa-What to advise patients and parents

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Balfour-Lynn Im
January 10, 2021
Comment / Editorial
Open Access

Conceptions of the pathophysiology of happy hypoxemia in COVID-19

Respiratory Research
Sebastiaan DhontBart N Lambrecht
December 15, 2020

Cyclic Peptidyl Inhibitors against CAL/CFTR Interaction for Treatment of Cystic Fibrosis

Journal of Medicinal Chemistry
Patrick G DoughertyDehua Pei
December 29, 2020

Minimal structural lung disease in early life represents significant pathology

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Shivanthan ShanthikumarSarath C Ranganathan
January 8, 2021
Comment / Editorial

Tribulations and (clinical) trials in cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
R Elaine Cagnina, Gregory S Sawicki
January 14, 2021
Open Access

Ruling out COVID-19 by chest CT at emergency admission when prevalence is low: the prospective, observational SCOUT study

Respiratory Research
Ulf TeichgräberPhilipp Reuken
December 29, 2020

VO2max as an exercise tolerance endpoint in people with cystic fibrosis: Lessons from a lumacaftor/ivacaftor trial

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
John WilsonDominic Keating
November 14, 2020
Open Access

The global impact of SARS-CoV-2 in 181 people with cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Elliot McClenaghanSiobhán B Carr
December 29, 2020
Open Access

The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label randomised crossover study (AZTEC-CF)

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Freddy FrostDilip Nazareth
December 21, 2020

Ototoxicity in cystic fibrosis patients receiving intravenous tobramycin for acute pulmonary exacerbation: Ototoxicity following tobramycin treatment

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
E Emily HarruffPatrick A Flume
December 15, 2020
Open Access

Amphotericin B induces epithelial voltage responses in people with cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Rajeev S ChorghadeMartin D Burke
January 5, 2021

Changes in fecal microbiota with CFTR modulator therapy: A pilot study

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
C E PopeL R Hoffman
December 16, 2020
Open Access

High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma

Respiratory Research
Ryota DokuniYoshihiro Nishimura
January 8, 2021
Comment / Editorial
Open Access

Happy hypoxemia, or blunted ventilation?

Respiratory Research
Josuel OraDenis O'Donnell
January 8, 2021
Open Access

Visceral adiposity index is associated with lung function impairment: a population-based study

Respiratory Research
Sunyue HeLi Qin
January 13, 2021

Relationship between airway dysbiosis, inflammation and lung function in adults with cystic fibrosis

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Dario L FreyAlexander H Dalpke
December 12, 2020
Open Access

A super-spreader of SARS-CoV-2 in incubation period among health-care workers

Respiratory Research
Chaojie WeiZhenshun Cheng

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