CFTR Mutant Structural Therapy

Over 1700 different mutations in the CFTR genes have been shown to cause cystic fibrosis. Here is the latest research on structural therapy for CFTR mutants.

August 5, 2020

Gene therapy for respiratory diseases; progress and a changing context

Human Gene Therapy
Eric Wfw AltonGerry McLachlan
July 13, 2020
Open Access

The need for fast-track, high-quality and low-cost studies about the role of the BCG vaccine in the fight against COVID-19

Respiratory Research
Marcos PereiraMaurício L Barreto
July 19, 2020
Open Access

The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia

Respiratory Research
Saira AhmadRobert Tarran
July 31, 2020
Review
Open Access

Tiotropium in chronic obstructive pulmonary disease - a review of clinical development

Respiratory Research
Antonio Anzueto, Marc Miravitlles
July 10, 2020
Preprint
Open Access

A Topological Switch Enables Misfolding of the Cystic Fibrosis Transmembrane Conductance Regulator

BioRxiv : the Preprint Server for Biology
July 10, 2020
Review
Open Access

Extracellular vesicles: novel communicators in lung diseases

Respiratory Research
Aradhana MohanNavneet K Dhillon
July 21, 2020

Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Emma De JongC F Arest
July 18, 2020

CFTR modulator therapy for cystic fibrosis caused by the rare c.3700A>G mutation

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Puay-Wah PhuanAlan S Verkman
August 5, 2020
Open Access

Impact of gastroesophageal reflux on longitudinal lung function and quantitative computed tomography in the COPDGene cohort

Respiratory Research
Arianne K BaldomeroCOPDGene Investigators
July 30, 2020
Review
Open Access

The pathophysiology of 'happy' hypoxemia in COVID-19

Respiratory Research
Sebastiaan DhontBart N Lambrecht
July 17, 2020

A four week trial of hypertonic saline in children with mild cystic fibrosis lung disease: Effect on mucociliary clearance and clinical outcomes

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Scott H DonaldsonStephanie D Davis

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