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Chagas Disease

Chagas Disease diagram by vetpathologist, Shutterstock
vetpathologist, Shutterstock

Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protist Trypanosoma cruzi. It is spread mostly by insects known as Triatominae, or "kissing bugs". The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or local swelling at the site of the bite. After 8–12 weeks, individuals enter the chronic phase of disease and in 60–70% it never produces further symptoms.The other 30–40% of people develop further symptoms 10–30 years after the initial infection, including enlargement of the ventricles of the heart in 20–30%, leading to heart failure. An enlarged esophagus or an enlarged colon may also occur in 10% of people. Discover the latest research on Chagas disease here.

Top 20 most recent papers
Heart Rhythm : the Official Journal of the Heart Rhythm Society

Efficacy and Safety of Combined Endocardial/Epicardial Catheter Ablation for Ventricular Tachycardia in Chagas Disease. A Randomized Controlled Study

Heart Rhythm : the Official Journal of the Heart Rhythm SocietyFebruary 23, 2020
Cristiano F PisaniMauricio Scanavacca
Frontiers in Immunology

Corrigendum: In silico Design of an Epitope-Based Vaccine Ensemble for Chagas Disease

Frontiers in ImmunologyFebruary 22, 2020
Lucas Michel-TodóJulio Alonso-Padilla
The American Journal of Tropical Medicine and Hygiene

Congenital Chagas Disease in the United States: The Effect of Commercially Priced Benznidazole on Costs and Benefits of Maternal Screening

The American Journal of Tropical Medicine and HygieneFebruary 27, 2020
Victoria Perez-ZetuneEileen Stillwaggon
Enfermedades infecciosas y microbiología clínica

Contributions of molecular techniques in the chronic phase of Chagas disease in the absence of treatment

Enfermedades infecciosas y microbiología clínicaFebruary 24, 2020
Elena SulleiroTomàs Pumarola
The Pediatric Infectious Disease Journal

The Clinical and Parasitologic Follow-up of Trypanosoma cruzi-infected Children in a Nonendemic Country

The Pediatric Infectious Disease JournalFebruary 25, 2020
Marina SimónManuel Segovia
The American Journal of Tropical Medicine and Hygiene

ELISA Saliva for Trypanosoma cruzi Antibody Detection: An Alternative for Serological Surveys in Endemic Regions

The American Journal of Tropical Medicine and HygieneFebruary 27, 2020
Léa Campos de OliveiraEster Cerdeira Sabino
Combinatorial Chemistry & High Throughput Screening

Macromolecular Targets of Antiparasitic Germacranolide Sesquiterpenoids: An In-Silico Investigation

Combinatorial Chemistry & High Throughput ScreeningFebruary 19, 2020
Phillip M Arnston, William N Setzer
Tropical Medicine and Infectious Disease

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

Tropical Medicine and Infectious DiseaseFebruary 22, 2020
Srinivasa P S RaoThierry T Diagana
Foodborne Pathogens and Disease

SYBR Green qPCR Technique for the Detection of Trypanosoma cruzi in Açaí Pulp

Foodborne Pathogens and DiseaseFebruary 21, 2020
Gabrielle Virgínia Ferreira CardosoCarina Martins de Moraes
Life Sciences

Clearing or subverting the enemy: Role of autophagy in protozoan infections

Life SciencesFebruary 24, 2020
George Ghartey-KwansahEmmanuel Kwasi Abu

Hemoglobin Reassembly of Antimicrobial Fragments from the Midgut of Triatoma infestans

BiomoleculesFebruary 14, 2020
Laura Cristina Lima Diniz, Pedro Ismael da Silva Junior
Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences

2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses

Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied SciencesFebruary 20, 2020
Georgeta Serban
Future Microbiology

Update on the major imported protozoan infections in travelers and migrants

Future MicrobiologyFebruary 18, 2020
Francesca F NormanRogelio López-Vélez
MMWR. Morbidity and Mortality Weekly Report

Autochthonous Chagas Disease - Missouri, 2018

MMWR. Morbidity and Mortality Weekly ReportFebruary 21, 2020
George TurabelidzeSusanne Enyeart

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