Chaperones & Protein Folding (Preprints)

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here are the latest preprints on chaperone proteins.

February 25, 2021
Preprint
Open Access

A precise and general FRET-based method for monitoring structural transitions in protein self-organization

BioRxiv : the Preprint Server for Biology
Q. WanArnold J Boersma
February 25, 2021
Preprint
Open Access

Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos

BioRxiv : the Preprint Server for Biology
Jing DuY. Fan
February 25, 2021
Preprint
Open Access

Identical Sequences, Different Behaviors: ProteinDiversity Captured at the Single-Molecule Level

BioRxiv : the Preprint Server for Biology
Rafael Tapia-RojoJ. Fernandez
February 24, 2021
Preprint
Open Access

The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes

BioRxiv : the Preprint Server for Biology
S. D. CarterPeter Walter
February 24, 2021
Preprint
Open Access

Cyclophilin A regulates protein phase separation and mitigates haematopoietic stem cell aging

BioRxiv : the Preprint Server for Biology
L. ManeixAndre Catic
February 24, 2021
Preprint
Open Access

The Host Interactome of Spike Expands the Tropism of SARS-CoV-2.

BioRxiv : the Preprint Server for Biology
Casimir BambergerJohn Yates
February 23, 2021
Preprint
Open Access

A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis

BioRxiv : the Preprint Server for Biology
Luke McAlaryJ. J. Yerbury
February 23, 2021
Preprint
Open Access

Chaperones Skp and SurA dynamically expand unfolded outer membrane protein X and synergistically disassemble oligomeric aggregates

BioRxiv : the Preprint Server for Biology
N. ChamachiMichael Schlierf
February 22, 2021
Preprint
Open Access

A spindle and thread-mechanism unblocks translation of N-terminally disordered proteins

BioRxiv : the Preprint Server for Biology
M. KaldmaeMichael Landreh
February 22, 2021
Preprint
Open Access

Chemical rescue of mutant proteins in living cells by naturally occurring small molecules

BioRxiv : the Preprint Server for Biology
D. S. HassellMichael A McMurray
February 21, 2021
Preprint
Open Access

Structure-based prediction of KDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

BioRxiv : the Preprint Server for Biology
J. K. VargaOra Schueler-Furman
February 11, 2021
Preprint
Open Access

Electrical Unfolding of Cytochrome c During Translocation Through a Nanopore Constriction

BioRxiv : the Preprint Server for Biology
P. TripathiMeni Wanunu
February 11, 2021
Preprint
Open Access

Autonomous epithelial folding induced by an intracellular mechano-polarity feedback loop

BioRxiv : the Preprint Server for Biology
F.-L. WenTatsuo Shibata
February 10, 2021
Preprint
Open Access

Protomer alignment modulates specificity of RNA substrate recognition by Ire1

BioRxiv : the Preprint Server for Biology
W. LiPeter Walter
February 9, 2021
Preprint
Open Access

pyconsFold: A fast and easy tool for modelling and docking using distance predictions.

BioRxiv : the Preprint Server for Biology
J. Lamb, Arne Elofsson
February 8, 2021
Preprint
Open Access

Loss of ClpP Function in Clostridioides difficile 630 Significantly Impacts Sporulation Systems

BioRxiv : the Preprint Server for Biology
C. E. BishopAdam S. Duerfeldt
February 7, 2021
Preprint
Open Access

Long non-coding RNAs bind to proteins relevant to the ethanol tolerance in yeast: a systems biology view

BioRxiv : the Preprint Server for Biology
L. F. MarquesGuilherme Targino Valente
February 6, 2021
Preprint
Open Access

Cotranslational folding of a periplasmic protein domain in Escherichia coli

BioRxiv : the Preprint Server for Biology
H. SandhuGunnar Von Heijne
February 6, 2021
Preprint
Open Access

Cancer cells adapt FAM134B-BiP complex mediated ER-phagy to survive hypoxic stress

BioRxiv : the Preprint Server for Biology
S. ChipurupalliNirmal Robinson
February 5, 2021
Preprint
Open Access

TRNP1 sequence, function and regulation co-evolve with cortical folding in mammals

BioRxiv : the Preprint Server for Biology
Wolfgang EnardM. Ohnuki

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