Cholesterol Synthesis in Inflammation & Remyelination

The inflammatory response is activated when demyelination occurs. Accumulation of excess myelin debris triggers cholesterol crystal formation. Cholesterol deposits in the CNS can overwhelm phagocytes resulting in impaired tissue regeneration. Here is the latest research on cholesterol synthesis in inflammation and remyelination.

January 13, 2022

The role of lipid metabolism in shaping the expansion and the function of regulatory T cells.

Clinical and Experimental Immunology
Alessandra Pinzon GrimaldosSilvia Piconese
December 11, 2021
Open Access

Neochlorogenic Acid Attenuates Hepatic Lipid Accumulation and Inflammation via Regulating miR-34a In Vitro.

International Journal of Molecular Sciences
Meng-Hsun YuChau-Jong Wang
December 6, 2021

Effect of Emodin on Hyperlipidemia and Hepatic Lipid Metabolism in Zebrafish Larvae Fed a High-Cholesterol Diet.

Chemistry & Biodiversity
Lin-Feng HeYun-Xia Li
December 3, 2021
Open Access

Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.

Drew WilfahrtVirginia Smith Shapiro
October 28, 2021

Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice.

Cell Reports
Stefan A BerghoffGesine Saher
October 7, 2021

Butyrate supplementation to pregnant mice elicits cytoprotection against colonic injury in the offspring.

Pediatric Research
Maria E BarbianRheinallt M Jones
October 6, 2021

Targeting cholesterol homeostasis in hematopoietic malignancies.

Andrea Brendolan, Vincenzo Russo
August 24, 2021

Salsalate reduces atherosclerosis through AMPKβ1 in mice.

Molecular Metabolism
Emily A DayGregory R Steinberg
August 23, 2021

TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination.

The Journal of Experimental Medicine
Garyfallia GounaMikael Simons
August 21, 2021

Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation.

Proceedings of the National Academy of Sciences of the United States of America
Catherine LarochelleFrauke Zipp
August 13, 2021
Open Access

Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

BioRxiv : the Preprint Server for Biology
S. BerghoffGesine Saher
August 13, 2021

Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol.

Proceedings of the National Academy of Sciences of the United States of America
Hao WangScott B Hansen

Sign up to follow this feed and discover related papers.

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved