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Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia diagram by Jose Luis Calvo, Shutterstock
Jose Luis Calvo, Shutterstock

Chronic myelogenous leukemia (cml) is a clonal hematopoietic stem cell disorder characterized by the translocation and resultant production of the constitutively activated bcr-abl tyrosine kinase. Here is the latest research on this disease.

Top 20 most recent papers

Correction: Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1

LeukemiaJanuary 16, 2020
H PfeiferO G Ottmann

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

BloodJanuary 15, 2020
Courtney D DiNardoAndrew H Wei

Long-term outcomes of Sleeping Beauty generated CD19specific CAR T-cell therapy for relapsed-refractory B-cell lymphomas

BloodJanuary 22, 2020
Samer SrourPartow Kebriaei
Blood Advances

Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

Blood AdvancesJanuary 23, 2020
Oscar BrückSatu Mustjoki
Expert Review of Hematology

What are the considerations for tyrosine kinase inhibitor discontinuation in chronic phase chronic myeloid leukaemia?

Expert Review of HematologyJanuary 19, 2020
Patrick HarringtonHugues de Lavallade
Nature Reviews. Cancer

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

Nature Reviews. CancerJanuary 8, 2020
David VetrieM Copland
American Journal of Hematology

Clinical Utility of Fluorescence In Situ Hybridization-based Diagnosis of BCR-ABL1 like (Philadelphia Chromosome like) B-Acute Lymphoblastic Leukemia

American Journal of HematologyJanuary 11, 2020
Theodora AnagnostouMrinal M Patnaik
British Journal of Haematology

BCR-ABL1-positive acute myeloid leukaemia relapsing as acute lymphoblastic leukaemia

British Journal of HaematologyJanuary 17, 2020
Xueyan Chen, Hongwei Chen
Molecules and Cells

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

Molecules and CellsJanuary 23, 2020
Asumi YokotaGang Huang
Journal of Cellular and Molecular Medicine

Knockout of LASP1 in CXCR4 expressing CML cells promotes cell persistence, proliferation and TKI resistance

Journal of Cellular and Molecular MedicineJanuary 21, 2020
Andreas B HerrmannJochen J Frietsch

A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease

LeukemiaJanuary 12, 2020
G A HorneM Copland
Cytometry. Part B, Clinical Cytometry

CD304/neuropilin-1 is a very useful and dependable marker for the measurable residual disease assessment of B-cell precursor acute lymphoblastic leukemia

Cytometry. Part B, Clinical CytometryJanuary 17, 2020
Pratyusha GudapatiPrashant R Tembhare
Pharmaceutical Medicine

Adverse Drug Reactions Involving Protein Kinase Inhibitors: A French Pharmacovigilance Database Study Comparing Safety in Younger and Older Patients (≥ 75 years) with Cancer

Pharmaceutical MedicineJanuary 15, 2020
Vincent ClapesPascale Olivier
Purinergic Signalling

Imatinib mesylate affects extracellular ATP catabolism and expression of NTPDases in a chronic myeloid leukemia cell line

Purinergic SignallingJanuary 20, 2020
Julia Biz WilligDiogo André Pilger
Acta Haematologica

Exosomes in Chronic Myeloid Leukemia: Are We Reading a New Reliable Message?

Acta HaematologicaJanuary 11, 2020
Simona BernardiDomenico Russo
Mediterranean Journal of Hematology and Infectious Diseases

Successful Planned Pregnancy through Vitrified-Warmed Embryo Transfer in a Woman with Chronic Myeloid Leukemia: Case Report and Literature Review

Mediterranean Journal of Hematology and Infectious DiseasesJanuary 15, 2020
Yuka FurukawaKeiya Fujimori
Journal of Experimental & Clinical Cancer Research : CR

De-regulated STAT5A/miR-202-5p/USP15/Caspase-6 regulatory axis suppresses CML cell apoptosis and contributes to Imatinib resistance

Journal of Experimental & Clinical Cancer Research : CRJanuary 19, 2020
Zi-Yuan NieJian-Min Luo
International Journal of Biological Macromolecules

Study of the binding affinity between imatinib and α-1 glycoprotein using nuclear spin relaxation and isothermal titration calorimetry

International Journal of Biological MacromoleculesJanuary 18, 2020
Mihaela MicMircea Bogdan

Inhibition of Xanthine Oxidoreductase Enhances the Potential of Tyrosine Kinase Inhibitors against Chronic Myeloid Leukemia

AntioxidantsJanuary 19, 2020
Marta Romo-GonzálezÁngel Hernández-Hernández
Annals of the New York Academy of Sciences

Betulinic acid restores imatinib sensitivity in BCR-ABL1 kinase-independent, imatinib-resistant chronic myeloid leukemia by increasing HDAC3 ubiquitination and degradation

Annals of the New York Academy of SciencesJanuary 14, 2020
Tingting LuJishi Wang

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