Cis-regulatory elements are regions DNA that regulate the transcription of neighbouring genes. Trans-regulatory elements are genomic loci that regulate the expression of distant genes. Here is the latest research on CREs and TREs.
Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.
Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.
In autoimmune diseases, the immune system responds and attacks self-antigens and damages or impairs the function of the tissues. The treatment for autoimmune diseases often involves immunosuppressive agents, but newer treatments are being investigated. Discover the latest research on autoimmune disease therapy here.
Glioblastoma is the most common and aggressive type of brain tumor. It contains a population of tumor initiating stem cell-like cells known as cancer stem cells. Investigations are ongoing into these cancer stem cells found in these solid tumors which are highly resistance to treatment. Here is the latest research on cancer stem cells in glioblastoma.
Cardiac regeneration enables the repair of irreversibly damaged heart tissue using cutting-edge science, including stem cell and cell-free therapy. Discover the latest research on cardiac regeneration here.
mRNA-based technology is being studied as a potential technology that could be used to reprogram cell fate. This technique provides the potential to generate safe reprogrammed cells that can be used for clinical applications. Here is the latest research on cell fate conversion by mRNA.
Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.
Cilia produce different signaling molecules including ciliary neurotrophic factor that modulate the expression of many processes throughout the body. Exploiting the signaling pathway may be a therapeutic strategy for promoting the growth of different cell types. Here is the latest research on ciliary signaling and growth.
Human craniofacial stem cells are recently discovered sources of putative mesenchymal stem cells that hold great promise for autogenic or allogenic cell therapy and tissue engineering. Here is the latest research.
DPP4 has the potential to truncate proteins. DPP4-mediated truncation of certain chemokines, interleukins, and colony stimulating factors have recently been linked to regulation of hematopoietic stem/progenitor cells. Given its role in tumor biology, it is also used as a marker for various cancers. Here is the latest research.