Feed Preview

Fast Growing

Cis & Trans Regulatory Elements

Cis & Trans Regulatory Elements diagram by Juan Gaertner, Shutterstock
Juan Gaertner, Shutterstock

Cis-regulatory elements are regions DNA that regulate the transcription of neighbouring genes. Trans-regulatory elements are genomic loci that regulate the expression of distant genes. Here is the latest research on CREs and TREs.

Top 20 most recent papers
PLoS Genetics

Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

PLoS GeneticsJanuary 22, 2020
Gregory R KeeleTerrence S Furey

TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1

NatureJanuary 10, 2020
Jie SuJoan Massagué
Molecular Cell

Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks

Molecular CellJanuary 19, 2020
Helen ZhuJüri Reimand
Genome Research

A HOTAIR regulatory element modulates glioma cell sensitivity to temozolomide through long-range regulation of multiple target genes

Genome ResearchJanuary 19, 2020
Lei ZhangWange Lu

On the origin and evolution of RNA editing in metazoans

bioRxivJanuary 19, 2020
Qiye LiGuojie Zhang

N6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription

ScienceJanuary 18, 2020
Jun LiuChuan He
Nature Communications

Genomic programming of IRF4-expressing human Langerhans cells

Nature CommunicationsJanuary 18, 2020
Sofia SirventMarta E Polak

Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

bioRxivJanuary 14, 2020
Dan LiangJason L Stein

Convergent genetic architecture underlies parallel pelvic reduction in genetically highly structured stickleback species

bioRxivJanuary 17, 2020
Petri M KemppainenJuha Merila
BMC Plant Biology

Differential expression of IDA (INFLORESCENCE DEFICIENT IN ABSCISSION)-like genes in Nicotiana benthamiana during corolla abscission, stem growth and water stress

BMC Plant BiologyJanuary 22, 2020
Daniel VentimillaFrancisco R Tadeo
Communications Biology

The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice

Communications BiologyJanuary 18, 2020
Tomoko MinamizakiYuji Yoshiko
Nucleic Acids Research

Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium

Nucleic Acids ResearchJanuary 21, 2020
Jun LiPin-Xian Xu
Cancer Science

TFAP4-uORF coding 66aa inhibits the malignant behavior of glioma cells via suppressing TFAP4/LINC00520/miR-520f-3p feedback loop

Cancer ScienceJanuary 17, 2020
Yipeng WangYunhui Liu

Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension

bioRxivJanuary 20, 2020
Gi Fay MokAndrea Munsterberg
Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology

The cellular stress response and temperature: Function, regulation, and evolution

Journal of Experimental Zoology. Part A, Ecological and Integrative PhysiologyJanuary 17, 2020
George N Somero
Journal of Bacteriology

Roles of TroA and TroR in metalloregulated growth and gene expression in Treponema denticola

Journal of BacteriologyJanuary 15, 2020
Prakaimuk SaraithongJ Christopher Fenno
Biotechnology Advances

Cyanobacterial sigma factors: Current and future applications for biotechnological advances

Biotechnology AdvancesJanuary 17, 2020
Amit SrivastavaRoman Sobotka

Generation of fruit postharvest gene datasets and a novel motif analysis tool for functional studies: uncovering links between peach fruit heat treatment and cold storage responses

PlantaJanuary 18, 2020
Mauro GismondiClaudia A Bustamante

An ancient satellite repeat controls gene expression and embryonic development in Aedes aegypti through a highly conserved piRNA

bioRxivJanuary 15, 2020
Rebecca HalbachRonald P. van Rij

Norway spruce deploys tissue specific canonical responses to acclimate to the cold

bioRxivJanuary 17, 2020
Alexander VergaraVaughan Hurry

See more papers from this feed

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Autoimmune Disease Therapy

In autoimmune diseases, the immune system responds and attacks self-antigens and damages or impairs the function of the tissues. The treatment for autoimmune diseases often involves immunosuppressive agents, but newer treatments are being investigated. Discover the latest research on autoimmune disease therapy here.

Cancer Stem Cells in Glioblastoma

Glioblastoma is the most common and aggressive type of brain tumor. It contains a population of tumor initiating stem cell-like cells known as cancer stem cells. Investigations are ongoing into these cancer stem cells found in these solid tumors which are highly resistance to treatment. Here is the latest research on cancer stem cells in glioblastoma.

Cardiac Regeneration

Cardiac regeneration enables the repair of irreversibly damaged heart tissue using cutting-edge science, including stem cell and cell-free therapy. Discover the latest research on cardiac regeneration here.

Cell Fate Conversion By mRNA

mRNA-based technology is being studied as a potential technology that could be used to reprogram cell fate. This technique provides the potential to generate safe reprogrammed cells that can be used for clinical applications. Here is the latest research on cell fate conversion by mRNA.

Chromatin Regulators: Differentiation

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.

Ciliary Signaling & Growth

Cilia produce different signaling molecules including ciliary neurotrophic factor that modulate the expression of many processes throughout the body. Exploiting the signaling pathway may be a therapeutic strategy for promoting the growth of different cell types. Here is the latest research on ciliary signaling and growth.

Craniofacial Stem Cells

Human craniofacial stem cells are recently discovered sources of putative mesenchymal stem cells that hold great promise for autogenic or allogenic cell therapy and tissue engineering. Here is the latest research.

Dpp4, Pluritpotency & Cancer Cells

DPP4 has the potential to truncate proteins. DPP4-mediated truncation of certain chemokines, interleukins, and colony stimulating factors have recently been linked to regulation of hematopoietic stem/progenitor cells. Given its role in tumor biology, it is also used as a marker for various cancers. Here is the latest research.

© 2020 Meta ULC. All rights reserved