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Classical Complement Pathway

Classical Complement Pathway diagram by undefined

The Classical Complement Pathway is activated by antigen-antibody complexes. Activation of this pathway leads to the generation of the membrane attack complex, which kills pathogenic cells. Discover the latest research on the Classical Complement Pathway here.

Top 20 most recent papers
Lancet Neurology

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

Lancet NeurologyDecember 3, 2019
Katrina M MooreFTD Prevention Initiative
101
Blood

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

BloodDecember 8, 2019
Shruti ChaturvediRobert Alan Brodsky
2
Gastroenterology

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension

GastroenterologyDecember 5, 2019
Naga P ChalasaniPeter G Traber
8
6
The Journal of Clinical Investigation

A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome

The Journal of Clinical InvestigationDecember 9, 2019
Ling P ZhaoZhao-xiang Bian
10
1
Liver International : Official Journal of the International Association for the Study of the Liver

Efficacy and Safety of Glecaprevir/Pibrentasvir in Renally-Impaired Patients with Chronic HCV Infection

Liver International : Official Journal of the International Association for the Study of the LiverDecember 10, 2019
Eric J LawitzMarcello Persico
3
bioRxiv

Age-related macular degeneration-like phenotypic features develop at the early ages of Cxcr5/Nrf2 double knockout mice: An accelerated AMD model

bioRxivDecember 8, 2019
Hu Huang, Anton Lennikov
3
Scientific Reports

Polymorphisms of MFGE8 are associated with susceptibility and clinical manifestations through gene expression modulation in Koreans with systemic lupus erythematosus

Scientific ReportsDecember 6, 2019
Wook-Young BaekChang-Hee Suh
Infection and Immunity

Bypassing phase variation of lipooligosaccharide (LOS): using heptose 1 glycan mutants to establish widespread efficacy of gonococcal 2C7 anti-LOS antibody

Infection and ImmunityDecember 9, 2019
Srinjoy ChakrabortiSanjay Ram
Scientific Reports

Bone secreted factors induce cellular quiescence in prostate cancer cells

Scientific ReportsDecember 9, 2019
Sue-Hwa LinSue-Hwa Lin
Frontiers in Immunology

Enolase From Aspergillus fumigatus Is a Moonlighting Protein That Binds the Human Plasma Complement Proteins Factor H, FHL-1, C4BP, and Plasminogen

Frontiers in ImmunologyNovember 22, 2019
Prasad DasariPeter F. Zipfel
PloS One

Clinically useful limited sampling strategy to estimate area under the concentration-time curve of once-daily tacrolimus in adult Japanese kidney transplant recipients

PloS OneDecember 11, 2019
Ryuto NakazawaHideo Sasaki
Antimicrobial Agents and Chemotherapy

Determining the development of persisters in extensively-drug resistant Acinetobacter baumannii upon exposure to polymyxin B-based antibiotic combinations using flow cytometry

Antimicrobial Agents and ChemotherapyDecember 9, 2019
Fiona Hui-Sian WongAndrea Lay-Hoon Kwa
2
Biochemistry

Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

BiochemistryDecember 11, 2019
Fumitaka KudoTadashi EGUCHI
The Journal of Immunology : Official Journal of the American Association of Immunologists

Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway"

The Journal of Immunology : Official Journal of the American Association of ImmunologistsDecember 11, 2019
Péter GálGábor Pál
International Journal of Rheumatic Diseases

Serum levels of interleukin-34 and clinical correlation in patients with primary Sjögren's syndrome

International Journal of Rheumatic DiseasesDecember 10, 2019
Yan-Mei LiuHui Shen
BMC Nephrology

Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis

BMC NephrologyDecember 10, 2019
Lin-Lin LiMing-Hui Zhao
Translational Stroke Research

Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage

Translational Stroke ResearchDecember 6, 2019
Bart J van DijkMervyn D I Vergouwen
Journal of Nephrology

Outcome of C3 glomerulopathy patients: largest single-centre experience from South Asia

Journal of NephrologyDecember 9, 2019
Ashwani KumarRakesh Kumar Vasishta
The Science of the Total Environment

A comparative study of the physiological and biochemical properties of tomato (Lycopersicon esculentum M.) and maize (Zea mays L.) under palladium stress

The Science of the Total EnvironmentDecember 4, 2019
Xiaohong ZhaoXiao-Yong Liao
1
The Journal of Immunology : Official Journal of the American Association of Immunologists

Response to Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway"

The Journal of Immunology : Official Journal of the American Association of ImmunologistsDecember 11, 2019
Takeshi MachidaHideharu Sekine

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