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Classical Complement Pathway
The Classical Complement Pathway is activated by antigen-antibody complexes. Activation of this pathway leads to the generation of the membrane attack complex, which kills pathogenic cells. Discover the latest research on the Classical Complement Pathway here.
Top 20 most recent papers
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study
Lancet NeurologyDecember 3, 2019
Katrina M MooreFTD Prevention Initiative
101
Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS
BloodDecember 8, 2019
Shruti ChaturvediRobert Alan Brodsky
2
Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension
GastroenterologyDecember 5, 2019
Naga P ChalasaniPeter G Traber
8
6
A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome
The Journal of Clinical InvestigationDecember 9, 2019
Ling P ZhaoZhao-xiang Bian
10
1
Efficacy and Safety of Glecaprevir/Pibrentasvir in Renally-Impaired Patients with Chronic HCV Infection
Liver International : Official Journal of the International Association for the Study of the LiverDecember 10, 2019
Eric J LawitzMarcello Persico
3
Age-related macular degeneration-like phenotypic features develop at the early ages of Cxcr5/Nrf2 double knockout mice: An accelerated AMD model
bioRxivDecember 8, 2019
Hu Huang, Anton Lennikov
3
Polymorphisms of MFGE8 are associated with susceptibility and clinical manifestations through gene expression modulation in Koreans with systemic lupus erythematosus
Scientific ReportsDecember 6, 2019
Wook-Young BaekChang-Hee Suh
Bypassing phase variation of lipooligosaccharide (LOS): using heptose 1 glycan mutants to establish widespread efficacy of gonococcal 2C7 anti-LOS antibody
Infection and ImmunityDecember 9, 2019
Srinjoy ChakrabortiSanjay Ram
Bone secreted factors induce cellular quiescence in prostate cancer cells
Scientific ReportsDecember 9, 2019
Sue-Hwa LinSue-Hwa Lin
Enolase From Aspergillus fumigatus Is a Moonlighting Protein That Binds the Human Plasma Complement Proteins Factor H, FHL-1, C4BP, and Plasminogen
Frontiers in ImmunologyNovember 22, 2019
Prasad DasariPeter F. Zipfel
Clinically useful limited sampling strategy to estimate area under the concentration-time curve of once-daily tacrolimus in adult Japanese kidney transplant recipients
PloS OneDecember 11, 2019
Ryuto NakazawaHideo Sasaki
Determining the development of persisters in extensively-drug resistant Acinetobacter baumannii upon exposure to polymyxin B-based antibiotic combinations using flow cytometry
Antimicrobial Agents and ChemotherapyDecember 9, 2019
Fiona Hui-Sian WongAndrea Lay-Hoon Kwa
2
Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis
BiochemistryDecember 11, 2019
Fumitaka KudoTadashi EGUCHI
Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway"
The Journal of Immunology : Official Journal of the American Association of ImmunologistsDecember 11, 2019
Péter GálGábor Pál
Serum levels of interleukin-34 and clinical correlation in patients with primary Sjögren's syndrome
International Journal of Rheumatic DiseasesDecember 10, 2019
Yan-Mei LiuHui Shen
Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis
BMC NephrologyDecember 10, 2019
Lin-Lin LiMing-Hui Zhao
Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage
Translational Stroke ResearchDecember 6, 2019
Bart J van DijkMervyn D I Vergouwen
Outcome of C3 glomerulopathy patients: largest single-centre experience from South Asia
Journal of NephrologyDecember 9, 2019
Ashwani KumarRakesh Kumar Vasishta
A comparative study of the physiological and biochemical properties of tomato (Lycopersicon esculentum M.) and maize (Zea mays L.) under palladium stress
The Science of the Total EnvironmentDecember 4, 2019
Xiaohong ZhaoXiao-Yong Liao
1
Response to Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway"
The Journal of Immunology : Official Journal of the American Association of ImmunologistsDecember 11, 2019
Takeshi MachidaHideharu Sekine