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Collaboration for AIDS Vaccine Discovery (CAVD)

Collaboration for AIDS Vaccine Discovery (CAVD) diagram by undefined

The Collaboration for AIDS Vaccine Discovery (CAVD) focuses on designing a variety of novel HIV vaccine candidates and advancing the most promising candidates to clinical trials. Follow this feed to stay up to date on this important research from the CAVD.

Top 20 most recent papers
Science

Lack of therapeutic efficacy of an antibody to α4 β7 in SIVmac251-infected rhesus macaques

ScienceSeptember 6, 2019
Peter AbbinkDan H Barouch
17
3
14
Science Translational Medicine

Multiple roles for HIV broadly neutralizing antibodies

Science Translational MedicineOctober 30, 2019
Barton F. HaynesJohn R. Mascola
4
1
Science Translational Medicine

Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa

Science Translational MedicineSeptember 18, 2019
Glenda E GrayLawrence J Corey
63
7
1
18
bioRxiv

Subordinate effect of -21M HLA-B dimorphism on NK cell repertoire diversity and function in HIV-1 infected individuals of African origin

bioRxivSeptember 30, 2019
Elia Moreno CuberoDimitra Peppa
21
Cell

Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans

CellSeptember 5, 2019
Thomas HaganBali Pulendran
368
18
7
208
1
2
Science Translational Medicine

Antigenic competition in CD4+ T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial

Science Translational MedicineNovember 20, 2019
Esper Georges KallasNicole A Frahm
36
Immunity

A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation

ImmunitySeptember 8, 2019
Tuan M TranPeter D. Crompton
61
5
1
25
The Journal of Clinical Investigation

Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

The Journal of Clinical InvestigationOctober 8, 2019
Scott D NeidichGeorgia D. Tomaras
17
3
1
7
Cell Host & Microbe

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01

Cell Host & MicrobeOctober 28, 2019
Dora PintoWinfried Weissenhorn
12
Cell Host & Microbe

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

Cell Host & MicrobeSeptember 11, 2019
Amarendra PeguYing Huang
26
8
The Lancet. HIV

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial

The Lancet. HIVOctober 12, 2019
Giuseppe PantaleoNIAID HIV Vaccine Trials Network
20
2
4
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

Chemoprophylaxis vaccination: Phase 1 study to explore stage-specific immunity to Plasmodium falciparum in U.S. adults

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of AmericaOctober 17, 2019
Sara A HealyPatrick Emmet Duffy
2
3
Scientific Reports

Chemotherapy-induced neuroinflammation is associated with disrupted colonic and bacterial homeostasis in female mice

Scientific ReportsNovember 11, 2019
Brett R LomanLeah M Pyter
25
8
Science Translational Medicine

A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

Science Translational MedicineAugust 28, 2019
Philip K EhrenbergRasmi Thomas
19
5
21
bioRxiv

Antibody against envelope protein from human endogenous retrovirus activates neutrophils in systemic lupus erythematosus

bioRxivSeptember 20, 2019
Maria TokuyamaAkiko Iwasaki
72
2
Cell Host & Microbe

Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR-/- Mice

Cell Host & MicrobeNovember 1, 2019
Rafael Assumpção LaroccaDan H Barouch
19
PLoS Pathogens

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

PLoS PathogensSeptember 17, 2019
Celia C. LaBrancheDavid Charles Montefiori
5
3
Proceedings of the National Academy of Sciences of the United States of America

Contribution of proteasome-catalyzed peptide cis -splicing to viral targeting by CD8+ T cells in HIV-1 infection

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 20, 2019
Wayne PaesPersephone Borrow
1
The Journal of Bone and Joint Surgery. American Volume

Applying to Orthopaedic Residency and Matching Rates: Analysis and Review of the Past 25 Years

The Journal of Bone and Joint Surgery. American VolumeSeptember 20, 2019
Adam Y Nasreddine, Robert C Gallo
3
2
bioRxiv

Systematic profiling of full-length immunoglobulin and T-cell receptor repertoire diversity in rhesus macaque through long read transcriptome sequencing

bioRxivSeptember 26, 2019
Hayden N BrochuXinxia Peng
15

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