Collaboration for AIDS Vaccine Discovery (CAVD)

The Collaboration for AIDS Vaccine Discovery (CAVD) focuses on designing a variety of novel HIV vaccine candidates and advancing the most promising candidates to clinical trials. Follow this feed to stay up to date on this important research from the CAVD.

September 3, 2020
Preprint
Open Access

Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma

MedRxiv : the Preprint Server for Health Sciences
H. YueEric S Fischer
August 7, 2020
Review
Open Access

Dissecting the antibody-OME: past, present, and future

Current Opinion in Immunology
Carolin LoosGalit Alter
August 4, 2020
Preprint
Open Access

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

BioRxiv : the Preprint Server for Biology
Yiska WeisblumPaul D Bieniasz
August 20, 2020
Preprint
Open Access

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

BioRxiv : the Preprint Server for Biology
R. ParkerNicola Ternette
September 15, 2020
Preprint

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

BioRxiv : the Preprint Server for Biology
A. SchaeferTimothy P. Sheahan
July 24, 2020
Open Access

Controlling the SARS-CoV-2 spike glycoprotein conformation

Nature Structural & Molecular Biology
Rory HendersonPriyamvada Acharya
July 22, 2020
Open Access

Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells

Proceedings of the National Academy of Sciences of the United States of America
Magnus A G HoffmannPamela J Bjorkman
August 17, 2020

The αβ TCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site

Proceedings of the National Academy of Sciences of the United States of America
Wonmuk HwangEllis L Reinherz
August 12, 2020
Open Access

SARS-CoV-2-specific ELISA development

Journal of Immunological Methods
Vicky RoyGalit Alter
August 15, 2020
Preprint
Open Access

Specificity and Performance of Nucleocapsid and Spike-based SARS-CoV-2 Serologic Assays

MedRxiv : the Preprint Server for Health Sciences
Zahra Rikhtegaran TehraniMohammad M Sajadi
September 4, 2020
Open Access

Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity

MSphere
Carolin LoosGalit Alter
August 18, 2020
Review
Open Access

Approaches and Challenges in SARS-CoV-2 Vaccine Development

Cell Host & Microbe
Gabriel DagottoDan H Barouch
August 29, 2020
Open Access

Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Tyler E MillerJochen K Lennerz
September 9, 2020
Review

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

Nature Medicine
Mohamed Abdel-MohsenBEAT-HIV Delaney Collaboratory to Cure HIV-1 infection
July 31, 2020
Open Access

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

Nature
Noe B MercadoDan H Barouch
September 2, 2020
Preprint
Open Access

Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth

BioRxiv : the Preprint Server for Biology
D. CizmeciBoris Julg
August 26, 2020
Open Access

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

Cell Host & Microbe
Peng ZhaoLance Wells
July 22, 2020
Preprint
Open Access

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

BioRxiv : the Preprint Server for Biology
Y. WeisblumPaul D Bieniasz

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