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Complement Pathway: Mannose-Binding Lectin

Complement Pathway: Mannose-Binding Lectin diagram by Swaminathan et al, Wikimedia
Swaminathan et al, Wikimedia

The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.

Top 20 most recent papers
PloS One

Platelet thrombus formation in eHUS is prevented by anti-MBL2

PloS OneDecember 28, 2019
R I KushakE F Grabowski
PLoS Neglected Tropical Diseases

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels

PLoS Neglected Tropical DiseasesApril 3, 2020
Hellen Weinschutz MendesIara J Taborda Messias-Reason
ACS Infectious Diseases

Unique cell surface mannan of yeast pathogen Candida auris with selective binding to IgG

ACS Infectious DiseasesApril 3, 2020
Lufeng YanRobert J Linhardt
Journal of Clinical Immunology

Complement Activation in 22q11.2 Deletion Syndrome

Journal of Clinical ImmunologyMarch 11, 2020
Dina GrindeTore G Abrahamsen
Clinical Reviews in Allergy & Immunology

The Immunopathology of Complement Proteins and Innate Immunity in Autoimmune Disease

Clinical Reviews in Allergy & ImmunologyDecember 14, 2019
Federica DefendiChantal Dumestre-Pérard
Chemistry, an Asian Journal

Biopolymer/Glycopolypeptide-Blended Scaffolds: Synthesis, Characterization and Cellular Interactions

Chemistry, an Asian JournalNovember 23, 2019
Vinita DhawareSayam Sen Gupta
PLoS Pathogens

Herpes simplex encephalitis in adult patients with MASP-2 deficiency

PLoS PathogensDecember 24, 2019
Stéphanie BibertPierre-Yves Bochud
Trends in Parasitology

Trypanosoma cruzi Calreticulin: Immune Evasion, Infectivity, and Tumorigenesis

Trends in ParasitologyMarch 20, 2020
Galia Ramírez-TolozaArturo Ferreira
Ear and Hearing

Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations

Ear and HearingJanuary 28, 2020
Elina KariIsabelle Schrauwen
Journal of Clinical Immunology

Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway

Journal of Clinical ImmunologyDecember 13, 2019
M Isabel García-LaordenCarlos Rodríguez-Gallego
Seminars in Arthritis and Rheumatism

Mechanisms determining the amelioration of rheumatoid arthritis in pregnancy: A systematic review

Seminars in Arthritis and RheumatismApril 1, 2020
Charles RaineIan Giles

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