Computational Cardiac Modeling

This feed focuses on developing and applying computational algorithms for cardiac modeling and modeling of the cardiovasculature. Here is the latest research.

September 16, 2021

RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy.

Cell Stem Cell
Tarek MagdyPaul W Burridge
September 14, 2021

Preclinical short QT syndrome models: studying the phenotype and drug-screening.

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Xuehui FanIbrahim El-Battrawy
September 14, 2021
Open Access

Cardiotoxicity assessment using 3D vascularized cardiac tissue consisting of human iPSC-derived cardiomyocytes and fibroblasts.

Molecular Therapy. Methods & Clinical Development
Kiyoshi TadanoYoshiki Sawa
September 10, 2021

Analysis of Clonal Composition in Human iPSC and ESC and Derived 2D and 3D Differentiated Cultures.

Methods in Molecular Biology
Bernat Del OlmoAngels Almenar-Queralt
September 10, 2021

Multiomics Method Enabled by Sequential Metabolomics and Proteomics for Human Pluripotent Stem-Cell-Derived Cardiomyocytes.

Journal of Proteome Research
Elizabeth F BayneYing Ge
September 10, 2021

CHIR99021 Promotes hiPSC-Derived Cardiomyocyte Proliferation in Engineered 3D Microtissues.

Advanced Healthcare Materials
Ramona HesselbarthFelix B Engel
September 7, 2021

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance.

Nature Communications
Miao CuiEric N Olson
September 6, 2021
Open Access

A consolidated AAV system for single-cut CRISPR correction of a common Duchenne muscular dystrophy mutation.

Molecular Therapy. Methods & Clinical Development
Yu ZhangEric N Olson
September 3, 2021
Open Access

Induced pluripotent stem cells derived cardiomyocytes from Duchenne Muscular Dystrophy patients in vitro.

Pakistan Journal of Medical Sciences
Fareeha Faizan Ghori, Mohsin Wahid
September 3, 2021

On computational classification of genetic cardiac diseases applying iPSC cardiomyocytes.

Computer Methods and Programs in Biomedicine
Martti JuholaKatriina Aalto-Setälä
August 31, 2021

Analysis of the response of human iPSC-derived cardiomyocyte tissue to ICaL block. A combined in vitro and in silico approach.

Computers in Biology and Medicine
Albert DasíBeatriz Trenor

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