Coronavirus Host Entry

The entry of coronaviruses into susceptible host cells is mediated by the viral S (Spike) glycoprotein. This feed covers latest findings about this complex process and the ongoing research efforts into finding therapeutics that can target the viral Spike protein and hence disrupt virus-cell fusion.

May 8, 2020

Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein

Journal of Clinical Pathology
Tahir S Pillay
May 27, 2020

Human neutralizing antibodies elicited by SARS-CoV-2 infection

Bin JuLinqi Zhang
May 21, 2020

SARS, MERS and SARS-CoV-2 (COVID-19) treatment: a patent review

Expert Opinion on Therapeutic Patents
José Adão Carvalho Nascimento JuniorMairim Russo Serafini
May 18, 2020

Novel Drugs Targeting the SARS-CoV-2/COVID-19 Machinery

Current Topics in Medicinal Chemistry
Ariane SternbergCord Naujokat
May 7, 2020

The viral, epidemiologic, clinical characteristics and potential therapy options for COVID-19: a review

European Review for Medical and Pharmacological Sciences
C Li, B-H Xu
May 12, 2020
ReviewOpen Access

A Precision Medicine Approach to SARS-CoV-2 Pandemic Management

Current Treatment Options in Allergy
Carlos D CrisciLeila Müller
May 25, 2020

COVID-19 and the nervous system

Journal of Neurovirology
Joseph R Berger
May 18, 2020

ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Christian A DevauxDidier Raoult
May 7, 2020
Open Access

DC/L-SIGNs of Hope in the COVID-19 Pandemic

Journal of Medical Virology
Adam Brufsky, Michael T Lotze
May 22, 2020

Potential Role of ACE2 in Coronavirus Disease 2019 (COVID-19) Prevention and Management

Journal of Translational Internal Medicine
Mengyuan LiuJianping Li

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Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

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