Coronavirus Protein Structures

Deciphering and comparing the proteins of different coronaviruses forms a basis for understanding SARS-CoV-2 evolution and virus-receptor interactions. This feed follows studies analyzing the structures of coronavirus proteins, thereby revealing potential drug target sites.

January 20, 2022
Preprint
Open Access

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants.

MedRxiv : the Preprint Server for Health Sciences
Zhaochun ChenPatrizia Farci
January 20, 2022
Open Access

Extended ensemble simulations of a SARS-CoV-2 nsp1-5'-UTR complex.

PLoS Computational Biology
Shun SakurabaHidetoshi Kono
January 13, 2022
Preprint
Open Access

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants

MedRxiv : the Preprint Server for Health Sciences
Z. ChenPatrizia Farci
January 13, 2022

Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.

Cell Chemical Biology
Valeria NapolitanoKrzysztof Pyrc
December 31, 2021
Open Access

A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants.

Frontiers in Immunology
Sisi ShanLinqi Zhang
December 30, 2021

Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein.

Emerging Microbes & Infections
Shiqi XuZhong Huang
December 26, 2021
Preprint
Open Access

Potential coupling between SARS-CoV-2 replicative fitness and interactions of its nucleoprotein with human 14-3-3 proteins

BioRxiv : the Preprint Server for Biology
K. V. TugaevaNikolai N. Sluchanko
December 6, 2021
Preprint
Open Access

Interactions of SARS-CoV-2 protein E with cell junctions and polarity PDZ-containing proteins

BioRxiv : the Preprint Server for Biology
Y. ZhuCelia Caillet-Saguy
December 1, 2021

Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot.

RNA
Christopher P Jones, Adrian R Ferré-D'Amaré
November 30, 2021
Preprint
Open Access

A human monoclonal antibody potently pan-neutralizes SARS-CoV-2 VOCs by targeting RBD invariant sites

BioRxiv : the Preprint Server for Biology
X. WangLilin Ye
November 13, 2021
Open Access

Exposing structural variations in SARS-CoV-2 evolution.

Scientific Reports
Jiaan YangGang Ren
November 10, 2021

Relaxed complex scheme and molecular dynamics simulation suggests small molecule inhibitor of human TMPRSS2 for combating COVID-19.

Journal of Biomolecular Structure & Dynamics
Said A H VuaiDaniel M Shadrack
November 9, 2021

Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2.

European Journal of Medicinal Chemistry
Yi-Ting WangDuo-Zhi Chen

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