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Corticobasal Degeneration (MDS)

Corticobasal Degeneration (MDS) diagram by Schaefer et al, PLOS One
Schaefer et al, PLOS One

Corticobasal Degeneration (CBD)is a rare, neurodegenerative disease of the cerebral cortex and the basal ganglia, characterized by movement disorders. Discover the latest research on CBD here.

Top 20 most recent papers
Cell

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

CellFebruary 8, 2020
Tamta ArakhamiaAnthony W P Fitzpatrick
180
4
4
1
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationJanuary 9, 2020
Adam M StaffaroniARTFL/LEFFTDS consortium
Alzheimer's Research & Therapy

CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia

Alzheimer's Research & TherapyJanuary 2, 2020
Samir Abu-RumeilehPiero Parchi
1
1
medRxiv

Metabolomic changes associated with frontotemporal lobar degeneration syndromes

medRxivFebruary 12, 2020
Alexander G MurleyJames B Rowe
The Journal of Experimental Medicine

Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

The Journal of Experimental MedicineDecember 12, 2019
Sneha NarasimhanVirginia M Y Lee
54
1
1
163
1
Neurology. Clinical Practice

Video research visits for atypical parkinsonian syndromes among Fox Trial Finder participants

Neurology. Clinical PracticeMarch 20, 2020
Christopher G TarolliJamie L Adams
5
1
1
Journal of Neuropathology and Experimental Neurology

Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD

Journal of Neuropathology and Experimental NeurologyJanuary 31, 2020
John L RobinsonJohn Q Trojanowski
2
1
Advances in Experimental Medicine and Biology

Structure of NFT: Biochemical Approach

Advances in Experimental Medicine and BiologyFebruary 26, 2020
Masato Hasegawa
1
Journal of Alzheimer's Disease : JAD

Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage

Journal of Alzheimer's Disease : JADMarch 8, 2020
Claudia CicognolaKina Höglund
1
1
International Review of Neurobiology

Progressive supranuclear palsy

International Review of NeurobiologyNovember 30, 2019
Nikolaos GiagkouMaria Stamelou
1
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

Confirmation of 123 I-FP-CIT-SPECT (ioflupane) quantification methods in dementia with Lewy body and other neurodegenerative disorders

Journal of Nuclear Medicine : Official Publication, Society of Nuclear MedicineMarch 22, 2020
Daniela D MaltaisVal J Lowe
4
1
NeuroImage. Clinical

Brain volume and flortaucipir analysis of progressive supranuclear palsy clinical variants

NeuroImage. ClinicalJanuary 15, 2020
Jennifer L WhitwellKeith A Josephs
9
1
Brain Sciences

Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies

Brain SciencesDecember 22, 2019
Masanori KuriharaAtsushi Iwata
1
19
2

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Alpha-Synuclein Aggregation (MDS)

Alpha-synucleins are small proteins that are believed to restrict the mobility of synpatic vesicles and inhibit neurotransmitter release. Aggregation of these proteins have been linked to several types of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease. Here is the latest research on α-synuclein aggregation.

Alpha-Synuclein Antibody Therapeutics (MDS)

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Astrocytes & Huntington’s Disease (MDS)

Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.

Ataxia telangiectasia (MDS)

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Atypical Parkinsonism (MDS)

Atypical Parkinsonism presents with the same signs and symptoms of Parkinson's disease, but do not respond to typical Parkionson's disease treatment with levodopa. Atypical Parkinsonism is thought to be associated with abnormal protein buildup within brain cells. Here is the latest on Atypical Parkinsonism.

Autophagy: Cancer & Parkinson (MDS)

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

BRAIN Initiative Cell Census Network (MDS)

The BRAIN Initiative Cell Census Network aims to identify and provide experimental access to the different brain cell types to determine their roles in health and disease. Discover the latest research from researchers in the BRAIN Initiative Cell Census Network here.

Basal ganglia in Parkinson's disease (MDS)

The basal ganglia is comprised of the neostriatum, the external and internal pallidal segments, the subthalamic nucleus, the substantia nigra pars reticulata, and the pars compacta of the substantia nigra. The basal ganglia circuitry is responsible for the correct execution of voluntary movements and is implicated in Parkinson's disease. Here is the latest research investigating the basal ganglia in Parkinson's disease.

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