COVID-19 Therapeutic Drug Development

Various research strategies are being deployed to control the COVID-19 pandemic, including a search for a vaccine. This feed covers primarily the ongoing research efforts that are focused on repurposing existing antiviral drugs and finding novel therapeutic treatments.

August 3, 2020

Antirheumatic Disease Therapies for the Treatment of COVID-19: A Systematic Review and Meta-analysis

Arthritis & Rheumatology
Michael PutmanCOVID-19 Global Rheumatology Alliance
August 4, 2020

The Uncertain Role of Corticosteroids in the Treatment of COVID-19

JAMA Internal Medicine
Theodore G LiouNathan D Hatton
August 1, 2020

Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis

Expert Review of Respiratory Medicine
Syed Shahzad HasanSyed Tabish Razi Zaidi
August 3, 2020
Review

The Pharmacokinetic and Pharmacodynamic Properties of Hydroxychloroquine and Dose Selection for COVID-19: Putting the Cart Before the Horse

Infectious Diseases and Therapy
Taylor MorrisetteMichael J Rybak
August 2, 2020

Identification of potential Mpro inhibitors for the treatment of COVID-19 by using systematic virtual screening approach

Molecular Diversity
Ashish M KanhedMange Ram Yadav
August 4, 2020
Review

Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Susmit MhatreVandana Patravale
August 4, 2020

Identification of potential drug candidates to combat COVID-19: a structural study using the main protease (mpro) of SARS-CoV-2

Journal of Biomolecular Structure & Dynamics
Pradeep SharmaSujata Sharma
August 3, 2020

A retrospective evaluation on the efficacy of Lopinavir/ritonavir and chloroquine to treat non-severe COVID-19 patients

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Guiju GaoZhihai Chen
August 1, 2020
Review
Open Access

Progress in the Research and Development of Anti-COVID-19 Drugs

Frontiers in Public Health
Lianzhou HuangYifei Wang
August 4, 2020

A deep learning framework for high-throughput mechanism-driven phenotype compound screening

BioRxiv : the Preprint Server for Biology
Thai-Hoang PhamPing Zhang
August 4, 2020

Evaluation of drugs for potential repurposing against COVID-19 using a tier-based scoring system

Antiviral Therapy
Michael A JarvisHeinz Feldmann
August 3, 2020

Inhaled corticosteroids in virus pandemics: a treatment for COVID-19?

The Lancet. Respiratory Medicine
Dan V Nicolau, Mona Bafadhel
August 1, 2020

The Multidimensional Challenge of Treating COVID-19: Remdesivir is a Foot in the Door

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Rajesh T Gandhi
August 1, 2020

Covid-19: Remdesivir probably reduces recovery time, but evidence is uncertain, panel finds

BMJ : British Medical Journal
Elisabeth Mahase
August 1, 2020

Drug treatments for covid-19: living systematic review and network meta-analysis

BMJ : British Medical Journal
Reed SiemieniukRomina Brignardello-Petersen
July 31, 2020
Review
Open Access

COVID-19 pneumonia

Der Internist
M Pfeifer, O W Hamer
August 1, 2020

Remdesivir for severe covid-19: a clinical practice guideline

BMJ : British Medical Journal
Bram RochwergGordon Guyatt
July 31, 2020

Antiviral potential of some novel structural analogs of standard drugs repurposed for the treatment of COVID-19

Journal of Biomolecular Structure & Dynamics
Mohamed F AlAjmiMd Tabish Rehman

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