CpG Sites

CpG sites are genomic loci where cytosine is followed by a guanine along its 5’ to 3’ direction. CpG sites are common in CpG islands and its methylation has been implicated in cancer, aging, and gene silencing. Here is the latest research.

July 11, 2020

Development and validation of a novel 15-CpG-based signature for predicting prognosis in triple-negative breast cancer

Journal of Cellular and Molecular Medicine
Yang PengShengchun Liu
July 10, 2020

Programming Multifaceted Pulmonary T-Cell Immunity by Combination Adjuvants

BioRxiv : the Preprint Server for Biology
July 12, 2020

Production of IL-18 Binding Protein by Radiosensitive and Radioresistant Cells in CpG-Induced Macrophage Activation Syndrome

The Journal of Immunology : Official Journal of the American Association of Immunologists
Mathilde HarelCem Gabay
July 10, 2020

CD73 acts as a prognostic biomarker and promotes progression and immune escape in pancreatic cancer

Journal of Cellular and Molecular Medicine
Qiangda ChenWenchuan Wu
July 9, 2020

Shotgun metagenomic data of root endophytic microbiome of maize (Zea mays L.)

Data in Brief
Olubukola Oluranti BabalolaAyansina Segun Ayangbenro
July 10, 2020

NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9

European Journal of Immunology
Abdul AhadSunil Raghav
July 7, 2020

Is CpG Density the Link between Epigenetic Aging and Lifespan?

Trends in Genetics : TIG
Emily M Bertucci, Benjamin B Parrott
July 11, 2020

Diversification of CpG-Island Promoters Revealed by Comparative Analysis Between Human and Rhesus Monkey Genomes

Mammalian Genome : Official Journal of the International Mammalian Genome Society
Saki AotoKohji Okamura
July 9, 2020

Hypomethylation Causes MIR21 Overexpression in Tumors

Molecular Therapy Oncolytics
Jun LuRonghua Xian
July 7, 2020

Grape pomace inhibits colon carcinogenesis by suppressing cell proliferation and inducing epigenetic modifications

The Journal of Nutritional Biochemistry
Qiyu TianMeijun Zhu
July 8, 2020
Open Access

Systemic Investigation of Promoter-wide Methylome and Genome Variations in Gout

International Journal of Molecular Sciences
Chia-Chun TsengShun-Jen Chang

Sign up to follow this feed and discover related papers.

Related Feeds

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

Autophagy: Cancer & Parkinson

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

© 2020 Meta ULC. All rights reserved