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CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Top 20 most recent papers

Transcription factor motifs in anterior insula gene-expression in mood disorder

bioRxivDecember 5, 2019

Mbemba JabbiHans A. Hofmann

Treg cell-based therapies: challenges and perspectives

Nature Reviews. ImmunologyDecember 6, 2019

Caroline RaffinJeffrey A. Bluestone

ZBED2 is an antagonist of Interferon Regulatory Factor 1 and modulates cell identity in pancreatic cancer

bioRxivDecember 6, 2019

Tim D D SomervilleChristopher R. Vakoc

Modeling and Optimizing Medium Composition for Shoot Regeneration of Chrysanthemum via Radial Basis Function-Non-dominated Sorting Genetic Algorithm-II (RBF-NSGAII)

Scientific ReportsDecember 3, 2019

Mohsen HesamiMasoud Tohidfar

Characterization, modelling and mitigation of gene expression burden in mammalian cells

bioRxivDecember 6, 2019

Timothy FreiVelia Siciliano

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer

Cell ResearchDecember 6, 2019

Shuaishuai TengDong Wang

Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

bioRxivDecember 6, 2019

Karolina StepniakBartek Wilczynski

Bioinformatics Approaches to Gain Insights into cis-Regulatory Motifs Involved in mRNA Localization

Advances in Experimental Medicine and BiologyJanuary 1, 2019

Louis Philip Benoit BouvretteEric Lécuyer

Blue light-triggered optogenetic system for treating uveal melanoma

OncogeneDecember 6, 2019

Ming-Liang ZhangXiaomin Zhang

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor

Chemical ScienceSeptember 28, 2019

Karishma KailassAndrew A Beharry

The Biogenesis and Precise Control of RNA m6 A Methylation

Trends in Genetics : TIGDecember 3, 2019

Hui-Lin HuangJian-jun Chen

Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer

Clinical EpigeneticsDecember 3, 2019

Debodipta DasPartha P Majumder

Core Element Cloning, Cis- Element Mapping and Serum Regulation of the Human EphB4 Promoter: A Novel TATA-Less Inr/MTE/DPE- Like Regulated Gene

GenesDecember 2, 2019

Pierluigi ScaliaAntonio Giordano

Immunotherapy in pediatric acute lymphoblastic leukemia

Cancer Metastasis ReviewsDecember 6, 2019

Hiroto Inaba, Ching-Hon Pui

Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis-A Phase I Study

Journal of Clinical MedicineDecember 2, 2019

Ellen IacobaeusKatarina Le Blanc

IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes

The Journal of Clinical InvestigationDecember 5, 2019

Takashi K SatohLars Einar French

Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies

Cancer Chemotherapy and PharmacologyDecember 6, 2019

James R TonraLan Huang

3'-UTRs and the Control of Protein Expression in Space and Time

Advances in Experimental Medicine and BiologyJanuary 1, 2019

Traude Helene BeilharzPeter R Boag

Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program

Suzan StellooWilbert Zwart

Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures

Bioorganic ChemistryNovember 26, 2019

Bárbara A RebeloM Rita Ventura

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