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CREs: Gene & Cell Therapy

CREs: Gene & Cell Therapy diagram by undefined

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Top 20 most recent papers
bioRxiv

Transcription factor motifs in anterior insula gene-expression in mood disorder

bioRxivDecember 5, 2019
Mbemba JabbiHans A. Hofmann
3
Nature Reviews. Immunology

Treg cell-based therapies: challenges and perspectives

Nature Reviews. ImmunologyDecember 6, 2019
Caroline RaffinJeffrey A. Bluestone
bioRxiv

ZBED2 is an antagonist of Interferon Regulatory Factor 1 and modulates cell identity in pancreatic cancer

bioRxivDecember 6, 2019
Tim D D SomervilleChristopher R. Vakoc
8
Scientific Reports

Modeling and Optimizing Medium Composition for Shoot Regeneration of Chrysanthemum via Radial Basis Function-Non-dominated Sorting Genetic Algorithm-II (RBF-NSGAII)

Scientific ReportsDecember 3, 2019
Mohsen HesamiMasoud Tohidfar
1
bioRxiv

Characterization, modelling and mitigation of gene expression burden in mammalian cells

bioRxivDecember 6, 2019
Timothy FreiVelia Siciliano
11
Cell Research

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer

Cell ResearchDecember 6, 2019
Shuaishuai TengDong Wang
bioRxiv

Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

bioRxivDecember 6, 2019
Karolina StepniakBartek Wilczynski
8
Advances in Experimental Medicine and Biology

Bioinformatics Approaches to Gain Insights into cis-Regulatory Motifs Involved in mRNA Localization

Advances in Experimental Medicine and BiologyJanuary 1, 2019
Louis Philip Benoit BouvretteEric Lécuyer
Oncogene

Blue light-triggered optogenetic system for treating uveal melanoma

OncogeneDecember 6, 2019
Ming-Liang ZhangXiaomin Zhang
Chemical Science

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor

Chemical ScienceSeptember 28, 2019
Karishma KailassAndrew A Beharry
2
6
Trends in Genetics : TIG

The Biogenesis and Precise Control of RNA m6 A Methylation

Trends in Genetics : TIGDecember 3, 2019
Hui-Lin HuangJian-jun Chen
Clinical Epigenetics

Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer

Clinical EpigeneticsDecember 3, 2019
Debodipta DasPartha P Majumder
1
Genes

Core Element Cloning, Cis- Element Mapping and Serum Regulation of the Human EphB4 Promoter: A Novel TATA-Less Inr/MTE/DPE- Like Regulated Gene

GenesDecember 2, 2019
Pierluigi ScaliaAntonio Giordano
Cancer Metastasis Reviews

Immunotherapy in pediatric acute lymphoblastic leukemia

Cancer Metastasis ReviewsDecember 6, 2019
Hiroto Inaba, Ching-Hon Pui
Journal of Clinical Medicine

Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis-A Phase I Study

Journal of Clinical MedicineDecember 2, 2019
Ellen IacobaeusKatarina Le Blanc
The Journal of Clinical Investigation

IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes

The Journal of Clinical InvestigationDecember 5, 2019
Takashi K SatohLars Einar French
Cancer Chemotherapy and Pharmacology

Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies

Cancer Chemotherapy and PharmacologyDecember 6, 2019
James R TonraLan Huang
Advances in Experimental Medicine and Biology

3'-UTRs and the Control of Protein Expression in Space and Time

Advances in Experimental Medicine and BiologyJanuary 1, 2019
Traude Helene BeilharzPeter R Boag
Endocrine-related Cancer

Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program

Endocrine-related CancerDecember 1, 2019
Suzan StellooWilbert Zwart
2
Bioorganic Chemistry

Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures

Bioorganic ChemistryNovember 26, 2019
Bárbara A RebeloM Rita Ventura

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