Feed Preview

CREs: Gene & Cell Therapy

CREs: Gene & Cell Therapy diagram by undefined

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Top 20 most recent papers

Transcription factor motifs in anterior insula gene-expression in mood disorder

bioRxivDecember 5, 2019
Mbemba JabbiHans A. Hofmann
Nature Reviews. Immunology

Treg cell-based therapies: challenges and perspectives

Nature Reviews. ImmunologyDecember 6, 2019
Caroline RaffinJeffrey A. Bluestone

ZBED2 is an antagonist of Interferon Regulatory Factor 1 and modulates cell identity in pancreatic cancer

bioRxivDecember 6, 2019
Tim D D SomervilleChristopher R. Vakoc
Scientific Reports

Modeling and Optimizing Medium Composition for Shoot Regeneration of Chrysanthemum via Radial Basis Function-Non-dominated Sorting Genetic Algorithm-II (RBF-NSGAII)

Scientific ReportsDecember 3, 2019
Mohsen HesamiMasoud Tohidfar

Characterization, modelling and mitigation of gene expression burden in mammalian cells

bioRxivDecember 6, 2019
Timothy FreiVelia Siciliano
Cell Research

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer

Cell ResearchDecember 6, 2019
Shuaishuai TengDong Wang

Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

bioRxivDecember 6, 2019
Karolina StepniakBartek Wilczynski
Advances in Experimental Medicine and Biology

Bioinformatics Approaches to Gain Insights into cis-Regulatory Motifs Involved in mRNA Localization

Advances in Experimental Medicine and BiologyJanuary 1, 2019
Louis Philip Benoit BouvretteEric Lécuyer

Blue light-triggered optogenetic system for treating uveal melanoma

OncogeneDecember 6, 2019
Ming-Liang ZhangXiaomin Zhang
Chemical Science

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor

Chemical ScienceSeptember 28, 2019
Karishma KailassAndrew A Beharry
Trends in Genetics : TIG

The Biogenesis and Precise Control of RNA m6 A Methylation

Trends in Genetics : TIGDecember 3, 2019
Hui-Lin HuangJian-jun Chen
Clinical Epigenetics

Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer

Clinical EpigeneticsDecember 3, 2019
Debodipta DasPartha P Majumder

Core Element Cloning, Cis- Element Mapping and Serum Regulation of the Human EphB4 Promoter: A Novel TATA-Less Inr/MTE/DPE- Like Regulated Gene

GenesDecember 2, 2019
Pierluigi ScaliaAntonio Giordano
Cancer Metastasis Reviews

Immunotherapy in pediatric acute lymphoblastic leukemia

Cancer Metastasis ReviewsDecember 6, 2019
Hiroto Inaba, Ching-Hon Pui
Journal of Clinical Medicine

Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis-A Phase I Study

Journal of Clinical MedicineDecember 2, 2019
Ellen IacobaeusKatarina Le Blanc
The Journal of Clinical Investigation

IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes

The Journal of Clinical InvestigationDecember 5, 2019
Takashi K SatohLars Einar French
Cancer Chemotherapy and Pharmacology

Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies

Cancer Chemotherapy and PharmacologyDecember 6, 2019
James R TonraLan Huang
Advances in Experimental Medicine and Biology

3'-UTRs and the Control of Protein Expression in Space and Time

Advances in Experimental Medicine and BiologyJanuary 1, 2019
Traude Helene BeilharzPeter R Boag
Endocrine-related Cancer

Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program

Endocrine-related CancerDecember 1, 2019
Suzan StellooWilbert Zwart
Bioorganic Chemistry

Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures

Bioorganic ChemistryNovember 26, 2019
Bárbara A RebeloM Rita Ventura

See more papers from this feed

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Alzheimer's Disease: Genetics

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Antisense Oligonucleotide - Therapies For ALS

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

© 2019 Meta ULC. All rights reserved