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Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease diagram by Mead et al, Wikimedia
Mead et al, Wikimedia

Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused due to aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.

Top 20 most recent papers
bioRxiv

Host prion protein expression levels impact prion tropism for the spleen

bioRxivDecember 17, 2019
Vincent BéringueHubert Laude
4
bioRxiv

Independent domestications shape the genetic pattern of a reproductive isolation system in rice

bioRxivJanuary 9, 2020
Xu xunZhang fumin
2
Acta Neuropathologica

PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins

Acta NeuropathologicaDecember 20, 2019
Grant T CorbettDominic M Walsh
34
1
Scientific Reports

Characterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains

Scientific ReportsJanuary 9, 2020
Romolo NonnoJan P M Langeveld
9
Proceedings of the National Academy of Sciences of the United States of America

The emergence of classical BSE from atypical/Nor98 scrapie

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 18, 2019
Alvina HuorOlivier Andreoletti
53
19
2
1
Journal of Neurochemistry

Cellular Models for Discovering Prion Disease Therapeutics: Progress and Challenges

Journal of NeurochemistryJanuary 17, 2020
Saffire H KranceJoel C Watts
12
Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms

Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter

Biochimica Et Biophysica Acta. Gene Regulatory MechanismsJanuary 14, 2020
Prashant PradhanBishwajit Kundu
Frontiers in Veterinary Science

Sheep Are Susceptible to the Bovine Adapted Transmissible Mink Encephalopathy Agent by Intracranial Inoculation and Have Evidence of Infectivity in Lymphoid Tissues

Frontiers in Veterinary ScienceDecember 19, 2019
Eric D CassmannJustin J Greenlee
6
1
Dementia and Neurocognitive Disorders

A Case of Creutzfeldt-Jakob Disease Presented as Rapid Progressive Parkinsonism

Dementia and Neurocognitive DisordersJanuary 17, 2020
Yoonah Park, Chan-Nyeong Lee
Veterinary Research

Goats naturally devoid of PrPC are resistant to scrapie

Veterinary ResearchJanuary 12, 2020
Øyvind SalvesenCecilie Ersdal
1
1
The Lancet Infectious Diseases

Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation

The Lancet Infectious DiseasesDecember 27, 2019
Lesley UttleyMatt Stevenson
19
1
Frontiers in Physiology

Length-Dependent Activation of Contractility and Ca-Transient Kinetics in Auxotonically Contracting Isolated Rat Ventricular Cardiomyocytes

Frontiers in PhysiologyJanuary 11, 2020
Oleg Lookin, Yuri Protsenko
1
IEEE Transactions on Neural Networks and Learning Systems

Discriminative Local Sparse Representation by Robust Adaptive Dictionary Pair Learning

IEEE Transactions on Neural Networks and Learning SystemsJanuary 17, 2020
Yulin SunMeng Wang
The Journal of Infectious Diseases

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation

The Journal of Infectious DiseasesJanuary 11, 2020
Juan Carlos EspinosaJuan María Torres
Molecular Neurobiology

Validation of Poly(Propylene Imine) Glycodendrimers Towards Their Anti-prion Conversion Efficiency

Molecular NeurobiologyDecember 19, 2019
Matthias SchmitzInga Zerr
1
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies

Pseudo-anticipation in Creutzfeldt - Jakob disease is Due to a Rhomboid Shaped Artifact

European Journal of Neurology : the Official Journal of the European Federation of Neurological SocietiesDecember 10, 2019
Oren S CohenJoab Chapman
Biomaterials

Self-assembly hollow manganese Prussian white nanocapsules attenuate Tau-related neuropathology and cognitive decline

BiomaterialsDecember 22, 2019
Xiaojun CaiHangrong Chen
2
1
Global Social Welfare : Research, Policy & Practice

Engaging Young Men as Community Health Leaders in an STI and Intimate Partner Violence Prevention Trial in Dar es Salaam, Tanzania

Global Social Welfare : Research, Policy & PracticeDecember 21, 2019
Lusajo J KajulaSuzanne Maman
PloS One

Quaking-induced conversion of prion protein on a thermal mixer accelerates detection in brains infected with transmissible spongiform encephalopathy agents

PloS OneDecember 13, 2019
Nadine KaelberLuisa Gregori
Prion

Chronic wasting disease associated with prion protein gene (PRNP ) variation in Norwegian wild reindeer (Rangifer tarandus )

PrionDecember 20, 2019
Mariella E GüereMichael A Tranulis
3

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