CRISPR for Genome Editing (Preprints)

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.

January 6, 2021
Preprint
Open Access

Genome-wide screening of circadian and non-circadian impact of Neat1 genetic deletion

BioRxiv : the Preprint Server for Biology
A. JacqAnne-Marie Francois-Bellan
December 10, 2020
Preprint
Open Access

Expanding the range of editable targets in the wheat genome using the variants of the Cas12a and Cas9 nucleases

BioRxiv : the Preprint Server for Biology
W. WangEduard Akhunov
December 22, 2020
Preprint
Open Access

AF10 (MLLT10) prevents somatic cell reprogramming through regulation of H3K79 methylation

BioRxiv : the Preprint Server for Biology
D. Ugurlu-CimenTamer T Onder
December 4, 2020
Preprint
Open Access

CRISPR-mediated deletion of the Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) improves human T cell function for adoptive T cell therapy

BioRxiv : the Preprint Server for Biology
S. PradeRose Zamoyska
December 20, 2020
Preprint
Open Access

A nucleotide-sensing endonuclease from the Gabija bacterial defense system

BioRxiv : the Preprint Server for Biology
R. ChengBin Zhu
December 13, 2020
Preprint
Open Access

TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models

BioRxiv : the Preprint Server for Biology
M. LongoPaola Dongiovanni
December 18, 2020
Preprint
Open Access

Developmental accumulation of gene body and transposon non-CpG methylation in the zebrafish brain

BioRxiv : the Preprint Server for Biology
Ozren BogdanovicD. Hesselson
December 16, 2020
Preprint
Open Access

The GPIbα intracellular tail - role in transducing VWF- and Collagen/GPVI-mediated signaling

BioRxiv : the Preprint Server for Biology
A. Constantinescu-BercuIsabelle I Salles-Crawley
December 21, 2020
Preprint
Open Access

Discovery of synthetic lethal and tumor suppressive paralog pairs in the human genome

BioRxiv : the Preprint Server for Biology
P. C. R. ParrishAlice H. Berger
December 29, 2020
Preprint
Open Access

Engineering large chromosomal deletions by CRISPR-Cas9

BioRxiv : the Preprint Server for Biology
T. F. EleveldBauke Ylstra
January 15, 2021
Preprint
Open Access

CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus Say

BioRxiv : the Preprint Server for Biology
D.-K. PurusothamanLuke Alphey
January 14, 2021
Preprint
Open Access

Functional strain redundancy and persistent phage infection in Swiss hard cheese starter cultures

BioRxiv : the Preprint Server for Biology
V. SomervillePhilipp Engel
January 2, 2021
Preprint
Open Access

Precise genomic deletions using paired prime editing

BioRxiv : the Preprint Server for Biology
J. ChoiJay Shendure
December 19, 2020
Preprint
Open Access

CRISPR-cas13 enzymology rapidly detects SARS-CoV-2 fragments in a clinical setting

MedRxiv : the Preprint Server for Health Sciences
W. A. KhanGregory J Tsongalis
December 24, 2020
Preprint
Open Access

Transgelin: A New Gene Involved in LDL Endocytosis Identified by a Genome-wide CRISPR-Cas9 Screen

BioRxiv : the Preprint Server for Biology
Diego LuceroA. T. Remaley
January 6, 2021
Preprint
Open Access

Maintenance of Complex I and respiratory super-complexes by NDUF-11 is essential for respiratory function, mitochondrial structure and health in C. elegans

BioRxiv : the Preprint Server for Biology
A. Knapp-WilsonIan Collinson
January 9, 2021
Preprint
Open Access

Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-cell Growth and Survival

BioRxiv : the Preprint Server for Biology
J.-H. LiangBenjamin Gewurz
January 14, 2021
Preprint
Open Access

Epidemiological and evolutionary consequences of CRISPR-Cas reactivity

BioRxiv : the Preprint Server for Biology
Hélène ChabasR. R. Regoes
December 18, 2020
Preprint
Open Access

A common genetic architecture enables the lossy compression of large CRISPR libraries

BioRxiv : the Preprint Server for Biology
B. ZhaoJustin Robert Pritchard

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