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CRISPR for Genome Editing (Preprints)
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Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.
Top 20 most recent papers
An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
bioRxivNovember 5, 2019
Mary Elizabeth MathyerCristina de Guzman Strong
4
Multiplex genomic edition in Ashbya gossypii using CRISPR-Cpf1
bioRxivNovember 8, 2019
Jose Luis RevueltaBirgit Hoff
6
Selective metabolic redundancy of Gpi1 allows for specific inhibition of inflammatory Th17 cells
bioRxivNovember 29, 2019
Lin WuDan R. Littman
11
1
Cellular Fitness Phenotypes of Cancer Target Genes in Cancer Therapeutics
bioRxivNovember 15, 2019
Bijesh GeorgeRakesh Kumar
8
Exhaustive reconstruction of the CRISPR locus in Mycobacterium tuberculosis complex using short reads
bioRxivNovember 16, 2019
Christophe GuyeuxGuislaine Refregier
12
A saturating mutagenesis CRISPR-Cas9 mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in embryonic stem cells
bioRxivNovember 22, 2019
Matthew C. CanverPartha Pratim Das
8
SNP-CRISPR: a web tool for SNP-specific genome editing
bioRxivNovember 19, 2019
Chiao-Lin ChenNorbert Perrimon
30
Anticipating xenogenic pollution at the source: Impact of sterilizations on DNA release from microbial cultures
bioRxivNovember 8, 2019
David Calderon FrancoDavid Gregory Weissbrodt
11
Structural modularity of the XIST ribonucleoprotein complex
bioRxivNovember 24, 2019
Zhipeng LuHoward Y. Chang
24
TP63, SOX2 and KLF5 Establish Core Regulatory Circuitry and Construct Cancer Specific Epigenome in Esophageal Squamous Cell Carcinoma
bioRxivNovember 6, 2019
Yan-Yi JiangHarold Phillip Koeffler
7
A minimal CRISPR-Cas3 system for genome engineering
bioRxivDecember 3, 2019
Bálint CsörgoJoseph Bondy-Denomy
80
Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes
bioRxivNovember 18, 2019
Aditi KulkarniJian-Nong Xu
10
Primed acquisition and microhomology-mediated end-joining cooperate to confer specific CRISPR immunity against invasive genetic elements
bioRxivNovember 6, 2019
Xiao-Jie WangNan Peng
6
RNA-guided Retargeting of Sleeping Beauty Transposition in Human Cells
bioRxivNovember 20, 2019
Adrian KovačZoltán Ivics
7
Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis
bioRxivNovember 13, 2019
Xin LiuJin Billy Li
16
TUTase mediated site-directed access to clickable chromatin employing CRISPR-dCas9
bioRxivNovember 20, 2019
Jerrin Thomas GeorgeSeergazhi G Srivatsan
13
Mitotic spindle elongation is driven by joint microtubule sliding action of kinesins KIF4A and EG5
bioRxivDecember 3, 2019
Kruno VukušićIva M. Tolic
21
Generation and molecular characterization of CRISPR/Cas9-induced mutations in 63 immunity-associated genes in tomato reveals specificity and a range of gene modifications
bioRxivNovember 8, 2019
Ning ZhangGregory Gerald Martin
49
GO: A functional reporter system to identify and enrich base editing activity
bioRxivDecember 3, 2019
Alyna KattiLukas E. Dow
29
Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity
bioRxivDecember 4, 2019
I H GANSJames A. Coffman
3