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CRISPR for Genome Editing (Preprints)

CRISPR for Genome Editing (Preprints)   diagram by

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers
bioRxiv

Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9.

bioRxivDecember 11, 2019
Kim SummersDavid A Hume
19
bioRxiv

A tool for browsing the Cancer Dependency Map reveals functional connections between genes and helps predict the efficacy and selectivity of candidate cancer drugs

bioRxivDecember 18, 2019
Kenichi ShimadaTimothy J Mitchison
15
bioRxiv

Extensive Mammalian Germline Genome Engineering

bioRxivDecember 22, 2019
Yanan YueLuhan Yang
194
2
1
bioRxiv

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
18
bioRxiv

Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

bioRxivDecember 13, 2019
Guislaine RefrégierChristophe Guyeux
8
bioRxiv

Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair

bioRxivDecember 20, 2019
Nidaa AbabnehKevin Talbot
20
bioRxiv

Mutations in the tomato gibberellin receptors suppresses xylem proliferation and reduces water loss under water-deficit conditions

bioRxivJanuary 6, 2020
Natanella Illouz-EliazDavid Weiss
26
bioRxiv

A broad mutational target explains an evolutionary trend

bioRxivDecember 19, 2019
Fabrice BesnardMarie-Anne Félix
4
bioRxiv

ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens

bioRxivDecember 8, 2019
Elizabeth Hutton, Adam Siepel
21
bioRxiv

Ares-GT: design of guide RNAs targeting multiple genes for CRISPR-Cas experiments

bioRxivJanuary 13, 2020
Eugenio G. Minguet
16
1
bioRxiv

Science communication in online media: influence of press releases on coverage of genetics and CRISPR

bioRxivDecember 16, 2019
Rafał Grochala
8
bioRxiv

Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

bioRxivDecember 10, 2019
Vinay Kumar BariAyala Meir
8
bioRxiv

CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea

bioRxivJanuary 20, 2020
Matthias HahnGabriel Scalliet
bioRxiv

kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9

bioRxivDecember 8, 2019
Mahmudur Rahman HeraAtif Rahman
7
bioRxiv

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

bioRxivJanuary 9, 2020
Mie F. PedersenHans Bräuner-Osborne
12
bioRxiv

Transient CRISPR immunity leads to coexistence with phages

bioRxivDecember 19, 2019
Sean MeadenEdze R Westra
43
bioRxiv

The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette
5
bioRxiv

RECAS9: Recombining wild species introgression via mitotic gene editing in barley

bioRxivJanuary 8, 2020
Shelly LazarEyal Fridman
10
bioRxiv

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

bioRxivJanuary 14, 2020
Carlee MacPherson CunninghamDarius Balciunas
13
bioRxiv

Principles for rational Cas13d guide design

bioRxivDecember 28, 2019
Hans-Hermann WesselsNeville E Sanjana
62

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