Feed Preview
CRISPR for Genome Editing (Preprints)
.jpg)
Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.
Top 20 most recent papers
Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9.
bioRxivDecember 11, 2019
Kim SummersDavid A Hume
19
A tool for browsing the Cancer Dependency Map reveals functional connections between genes and helps predict the efficacy and selectivity of candidate cancer drugs
bioRxivDecember 18, 2019
Kenichi ShimadaTimothy J Mitchison
15
Extensive Mammalian Germline Genome Engineering
bioRxivDecember 22, 2019
Yanan YueLuhan Yang
194
2
1
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing
bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
18
Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis
bioRxivDecember 13, 2019
Guislaine RefrégierChristophe Guyeux
8
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair
bioRxivDecember 20, 2019
Nidaa AbabnehKevin Talbot
20
Mutations in the tomato gibberellin receptors suppresses xylem proliferation and reduces water loss under water-deficit conditions
bioRxivJanuary 6, 2020
Natanella Illouz-EliazDavid Weiss
26
A broad mutational target explains an evolutionary trend
bioRxivDecember 19, 2019
Fabrice BesnardMarie-Anne Félix
4
ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens
bioRxivDecember 8, 2019
Elizabeth Hutton, Adam Siepel
21
Ares-GT: design of guide RNAs targeting multiple genes for CRISPR-Cas experiments
bioRxivJanuary 13, 2020
Eugenio G. Minguet
16
1
Science communication in online media: influence of press releases on coverage of genetics and CRISPR
bioRxivDecember 16, 2019
Rafał Grochala
8
Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca
bioRxivDecember 10, 2019
Vinay Kumar BariAyala Meir
8
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea
bioRxivJanuary 20, 2020
Matthias HahnGabriel Scalliet
kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9
bioRxivDecember 8, 2019
Mahmudur Rahman HeraAtif Rahman
7
Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
bioRxivJanuary 9, 2020
Mie F. PedersenHans Bräuner-Osborne
12
Transient CRISPR immunity leads to coexistence with phages
bioRxivDecember 19, 2019
Sean MeadenEdze R Westra
43
The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis
bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette
5
RECAS9: Recombining wild species introgression via mitotic gene editing in barley
bioRxivJanuary 8, 2020
Shelly LazarEyal Fridman
10
Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes
bioRxivJanuary 14, 2020
Carlee MacPherson CunninghamDarius Balciunas
13
Principles for rational Cas13d guide design
bioRxivDecember 28, 2019
Hans-Hermann WesselsNeville E Sanjana
62