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CRISPR for Genome Editing

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Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Nature BiotechnologyDecember 9, 2019

David N. NguyenAlexander Marson

Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus

Scientific ReportsDecember 9, 2019

Jill M GoldsteinAmy J. Wagers

The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans

Genome BiologyDecember 10, 2019

Alejandro Isana Vasquez-RifoVictor R Ambros

Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer

OncogeneDecember 10, 2019

Hilal SaraçNathan A Lack

ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens

bioRxivDecember 8, 2019

Elizabeth R. Hutton, Adam C Siepel

Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

bioRxivDecember 10, 2019

Vinay Kumar BariAyala Meir

Rare BRIP1 missense alleles confer risk for ovarian and breast cancer

Cancer ResearchDecember 10, 2019

Cassandra L MoyerPaul J Goodfellow

kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9

bioRxivDecember 8, 2019

Mahmudur Rahman HeraAtif Hasan Rahman

The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

bioRxivDecember 8, 2019

Nicholas A. WoodScot P Ouellette

NickSeq for genome-wide strand-specific identification of DNA single-strand break sites with single nucleotide resolution

bioRxivDecember 10, 2019

Joshua J ElacquaPaul C. Blainey

Comparative proximity biotinylation produces an inventory of RAB18-interactions and implicates RAB18 in cholesterol mobilization

bioRxivDecember 10, 2019

Robert Scott KissMark T W Handley

Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer

OncogeneDecember 10, 2019

Joel Martín-PadronPedro Pablo Medina

Chromosomal length reference assembly for Diaphorina citri using single-molecule sequencing and Hi-C proximity ligation with manually curated genes in developmental, structural and immune pathways

bioRxivDecember 10, 2019

Prashant S HosmaniSurya Saha

Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease

Nature CommunicationsDecember 11, 2019

Tomoyuki TsukiyamaMasatsugu Ema

Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 10, 2019

Divine-Fondzenyuy LawirThomas L Boehm

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA

Analytical ChemistryDecember 9, 2019

Xiao Xia DaiYinsheng Wang

Host-informed expression of CRISPR guide RNA for genomic engineering in Komagataella phaffii

ACS Synthetic BiologyDecember 11, 2019

Neil Chandra DalvieJ Christopher Love

Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania

Nature CommunicationsDecember 9, 2019

Arijit BhattacharyaMarc Ouellette

CRISPR: the movie

NatureDecember 1, 2019

Amy Maxmen

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes )

Frontiers in MicrobiologyNovember 21, 2019

Thomas IpoutchaPascal Sirand-Pugnet

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