CRISPR for Genome Editing

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

February 23, 2021
Open Access

Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis

BioRxiv : the Preprint Server for Biology
Theresa CaseyK. M. Plaut
February 24, 2021

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.

Proceedings of the National Academy of Sciences of the United States of America
Kartik N RajagopalanChao Lu
February 24, 2021

Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13.

Molecular Cancer Research : MCR
Maria Francesca BaiettiAnna A Sablina
February 24, 2021

Enhancing grain-yield-related traits by CRISPR-Cas9 promoter editing of maize CLE genes.

Nature Plants
Lei LiuDavid Jackson
February 24, 2021
Open Access

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR-Cas12a gRNA switch.

Nucleic Acids Research
Scott P CollinsChase L Beisel
February 24, 2021

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.

Rajesh SomasundaramMikael Sigvardsson
February 24, 2021
Open Access

Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.

Nucleic Acids Research
Chengyong WuQiang Chen
February 24, 2021

Different functional roles of RTR complex factors in DNA repair and meiosis in Arabidopsis and tomato.

The Plant Journal : for Cell and Molecular Biology
Amy Leanne WhitbreadHolger Puchta
February 24, 2021

Natural Competence and Horizontal Gene Transfer in Campylobacter.

Current Topics in Microbiology and Immunology
Julia Carolin Golz, Kerstin Stingl
February 24, 2021

Polymer-Coated NH2-UiO-66 for the Codelivery of DOX/pCRISPR.

ACS Applied Materials & Interfaces
Navid RabieeMohammadreza Shokouhimehr
February 24, 2021

Gene editing technology: Towards precision medicine in inherited retinal diseases.

Seminars in Ophthalmology
Brian G BalliosRachel M Huckfeldt
February 24, 2021

Evidence that a naturally occurring single nucleotide polymorphism in the RagC gene of Leishmania donovani contributes to reduced virulence.

PLoS Neglected Tropical Diseases
Patrick LypaczewskiGreg Matlashewski
February 22, 2021

CRISPR/Cas9-mediated knockout of the NlCSAD gene results in darker cuticle pigmentation and a reduction in female fecundity in Nilaparvata lugens (Hemiptera: Delphacidae).

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Jing-Xiang ChenWen-Qing Zhang

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