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CRISPR for Genome Editing

CRISPR for Genome Editing diagram by Soleil Nordic, Shutterstock
Soleil Nordic, Shutterstock

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers
IScience

rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

IScienceJanuary 14, 2020
Gang PanClaes Wadelius
1
Nature Biotechnology

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Nature BiotechnologyJanuary 15, 2020
Marco JostJonathan S Weissman
117
1
Molecular Cell

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity

Molecular CellJanuary 15, 2020
Rebecca K LauKevin D Corbett
21
6
1
MSystems

Network-Based Prediction of Novel CRISPR-Associated Genes in Metagenomes

MSystemsJanuary 16, 2020
Jake L Weissman, Philip L F Johnson
12
Molecular and Cellular Biology

ZFP628 is a TAF4b-interacting transcription factor required for mouse spermiogenesis

Molecular and Cellular BiologyJanuary 15, 2020
Eric A GustafsonRichard N Freiman
2
Trends in Plant Science

Revisiting the Role of Master Regulators in Tomato Ripening

Trends in Plant ScienceJanuary 14, 2020
Rufang WangRuud A de Maagd
1
bioRxiv

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
14
Genes

Comparative Genomics Analysis of Lactobacillus ruminis from Different Niches

GenesJanuary 16, 2020
Shuo WangWei Chen
3
Journal of the American Chemical Society

Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks

Journal of the American Chemical SocietyJanuary 15, 2020
Mram Z AlyamiNiveen M Khashab
bioRxiv

Genetic ablation of the mitochondrial ribosome in Plasmodium falciparum sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functions

bioRxivJanuary 14, 2020
Liqin LingHangjun Ke
3
Cancers

Mutant IDH1 Depletion Downregulates Integrins and Impairs Chondrosarcoma Growth

CancersJanuary 16, 2020
Luyuan LiJonathan C Trent
7
MBio

A CRISPR Interference System for Efficient and Rapid Gene Knockdown in Caulobacter crescentus

MBioJanuary 16, 2020
Mathilde GuzzoMichael T Laub
71
bioRxiv

Designing and implementing programmable depletion in sequencing libraries with DASHit

bioRxivJanuary 13, 2020
David DynermanEmily Dawn Crawford
3
bioRxiv

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

bioRxivJanuary 14, 2020
Gopal KushawahMiguel Angel Moreno-Mateos
127
bioRxiv

TOP the Transcription Orientation Pipeline and its use to investigate the transcription of non-coding regions: assessment with CRISPR direct repeats and intergenic sequences.

bioRxivJanuary 15, 2020
Kimberley HouenoussiChristine Pourcel
6
bioRxiv

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

bioRxivJanuary 14, 2020
Carlee MacPherson CunninghamDarius Balciunas
13
Journal of Molecular Endocrinology

Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell line

Journal of Molecular EndocrinologyJanuary 16, 2020
Takumi NakamuraTakashi Tsuboi
1
Methods in Molecular Biology

CRISPR/Cas9-Based Genetic Screening to Study T-Cell Function

Methods in Molecular BiologyJanuary 15, 2020
Wanjing ShangHaopeng Wang
1
bioRxiv

Comparison of CRISPR and marker based methods for the engineering of phage T7

bioRxivJanuary 13, 2020
Aurelija M GrigonyteAndrew D Millard
6
Pathogens

CRISPR-cas3 of Salmonella Upregulates Bacterial Biofilm Formation and Virulence to Host Cells by Targeting Quorum-Sensing Systems

PathogensJanuary 16, 2020
Luqing CuiMenghong Dai
1

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