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CRISPR for Genome Editing

CRISPR for Genome Editing diagram by Soleil Nordic, Shutterstock
Soleil Nordic, Shutterstock

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers
Nature

The promise and challenge of therapeutic genome editing

NatureFebruary 14, 2020
Jennifer A Doudna
627
2
3
1
bioRxiv

Efficient immune cell genome engineering with improved CRISPR editing tools

bioRxivFebruary 14, 2020
Waipan ChanRonald N Germain
10
Cancer Research

Build-a-Mouse: Melanoma Modeling Picks up Speed

Cancer ResearchFebruary 16, 2020
Andres ThorkelssonHelen Michael
4
Methods in Enzymology

Temporal and rheostatic control of genome editing with a chemically-inducible Cas9

Methods in EnzymologyFebruary 13, 2020
Cindy T WeiDouglas M Fowler
1
Nature

Clades of huge phages from across Earth's ecosystems

NatureFebruary 14, 2020
Basem Al-ShayebJillian F Banfield
536
19
3
Investigative Ophthalmology & Visual Science

Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression

Investigative Ophthalmology & Visual ScienceFebruary 13, 2020
Emil CarlssonLuminita Paraoan
1
bioRxiv

Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome

bioRxivFebruary 12, 2020
Syed-Rehan A HussainK John McLaughlin
25
Briefings in Functional Genomics

CRISPR/Cas9 for cancer treatment: technology, clinical applications and challenges

Briefings in Functional GenomicsFebruary 14, 2020
Xing ChenXianfa Du
2
bioRxiv

Faster and better CRISPR guide RNA design with the Crackling method

bioRxivFebruary 15, 2020
Jacob BradfordDimitri Perrin
12
Briefings in Functional Genomics

Application of CRISPR/Cas9 technology in sepsis research

Briefings in Functional GenomicsFebruary 15, 2020
Miao WuJie Wei
Frontiers in Microbiology

Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9

Frontiers in MicrobiologyFebruary 13, 2020
Mark Andrew MoosburnerAndrew E Allen
6
Genetics and Molecular Biology

Underrated Staphylococcus species and their role in antimicrobial resistance spreading

Genetics and Molecular BiologyFebruary 14, 2020
Ciro César RossiMarcia Giambiagi-deMarval
1
International Journal of Biological Macromolecules

CRISPR/Cas9-mediated deletion of β, β-carotene 9', 10'-oxygenase gene (EcBCO2) from Exopalaemon carinicauda

International Journal of Biological MacromoleculesFebruary 15, 2020
Yuying SunJiquan Zhang

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