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CRISPR for Genome Editing

CRISPR for Genome Editing diagram by Soleil Nordic, Shutterstock
Soleil Nordic, Shutterstock

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers
Nature Genetics

Modeling the complex genetic architectures of brain disease

Nature GeneticsMarch 24, 2020
Michael B FernandoKristen J Brennand
49
2
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Generation of genetically engineered mouse lung organoid models for squamous cell lung cancers allows for the study of combinatorial immunotherapy

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchMarch 27, 2020
Josephine HaiKwok-Kin Wong
Nature Methods

Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies

Nature MethodsMarch 24, 2020
Nicole D MarinoJoseph Bondy-Denomy
42
New Biotechnology

Multiplex genome editing in Ashbya gossypii using CRISPR-Cpf1

New BiotechnologyMarch 21, 2020
Alberto JiménezJosé Luis Revuelta
The Journal of Investigative Dermatology

Research Techniques Made Simple: CRISPR Genetic Screens

The Journal of Investigative DermatologyMarch 24, 2020
Auke B C Otten, Bryan K Sun
1
Molecular Psychiatry

Regulatory mechanisms of major depressive disorder risk variants

Molecular PsychiatryMarch 28, 2020
Shiwu LiXiong-Jian Luo
International Journal of Molecular Sciences

Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons

International Journal of Molecular SciencesMarch 27, 2020
Magdalena MeyerBenjamin Jurek
Bioscience Reports

Gene editing and CRISPR in the clinic: current and future perspectives

Bioscience ReportsMarch 25, 2020
Matthew P HirakawaKimberly S Butler
2
Biochemical and Biophysical Research Communications

Establishment of a tTA-dependent photoactivatable Cre recombinase knock-in mouse model for optogenetic genome engineering

Biochemical and Biophysical Research CommunicationsMarch 25, 2020
Tomoka TakaoTakeshi Takarada
bioRxiv

Bar-seq strategies for the LeishGEdit toolbox

bioRxivMarch 20, 2020
Tom Beneke, Eva Gluenz
3
International Journal of Biological Sciences

Engineering Cellular Signal Sensors based on CRISPR-sgRNA Reconstruction Approaches

International Journal of Biological SciencesMarch 27, 2020
Hengji ZhanYuchen Liu

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