Feed Preview

CRISPR for Genome Editing

CRISPR for Genome Editing diagram by #N/A
#N/A

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Top 20 most recent papers
Nature Biotechnology

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Nature BiotechnologyDecember 9, 2019
David N. NguyenAlexander Marson
46
Scientific Reports

Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus

Scientific ReportsDecember 9, 2019
Jill M GoldsteinAmy J. Wagers
Genome Biology

The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans

Genome BiologyDecember 10, 2019
Alejandro Isana Vasquez-RifoVictor R Ambros
Oncogene

Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer

OncogeneDecember 10, 2019
Hilal SaraçNathan A Lack
bioRxiv

ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens

bioRxivDecember 8, 2019
Elizabeth R. Hutton, Adam C Siepel
21
bioRxiv

Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

bioRxivDecember 10, 2019
Vinay Kumar BariAyala Meir
7
Cancer Research

Rare BRIP1 missense alleles confer risk for ovarian and breast cancer

Cancer ResearchDecember 10, 2019
Cassandra L MoyerPaul J Goodfellow
bioRxiv

kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9

bioRxivDecember 8, 2019
Mahmudur Rahman HeraAtif Hasan Rahman
6
bioRxiv

The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette
5
bioRxiv

NickSeq for genome-wide strand-specific identification of DNA single-strand break sites with single nucleotide resolution

bioRxivDecember 10, 2019
Joshua J ElacquaPaul C. Blainey
23
bioRxiv

Comparative proximity biotinylation produces an inventory of RAB18-interactions and implicates RAB18 in cholesterol mobilization

bioRxivDecember 10, 2019
Robert Scott KissMark T W Handley
3
Oncogene

Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer

OncogeneDecember 10, 2019
Joel Martín-PadronPedro Pablo Medina
bioRxiv

Chromosomal length reference assembly for Diaphorina citri using single-molecule sequencing and Hi-C proximity ligation with manually curated genes in developmental, structural and immune pathways

bioRxivDecember 10, 2019
Prashant S HosmaniSurya Saha
9
Nature Communications

Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease

Nature CommunicationsDecember 11, 2019
Tomoyuki TsukiyamaMasatsugu Ema
Proceedings of the National Academy of Sciences of the United States of America

Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 10, 2019
Divine-Fondzenyuy LawirThomas L Boehm
Analytical Chemistry

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA

Analytical ChemistryDecember 9, 2019
Xiao Xia DaiYinsheng Wang
1
ACS Synthetic Biology

Host-informed expression of CRISPR guide RNA for genomic engineering in Komagataella phaffii

ACS Synthetic BiologyDecember 11, 2019
Neil Chandra DalvieJ Christopher Love
Nature Communications

Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania

Nature CommunicationsDecember 9, 2019
Arijit BhattacharyaMarc Ouellette
24
Nature

CRISPR: the movie

NatureDecember 1, 2019
Amy Maxmen
Frontiers in Microbiology

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes )

Frontiers in MicrobiologyNovember 21, 2019
Thomas IpoutchaPascal Sirand-Pugnet

See more papers from this feed

Related Feeds

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Adult Kidney Organoids at Single Cell Resolution

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Alzheimer's Disease: RNA Sequencing

RNA sequencing is used to reveal the presence and quantity of RNA in a given sample. In this feed, RNA sequencing investigates the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). Here are the latest discoveries pertaining to RNA sequencing and this disease.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Artificial Cell Models

This feed focuses on biomimetrics, synthetic biology and bio- and tissue-engineering approaches used for modeling human diseases.

Artificial Chromosomes

Artificial chromosomes are genetically engineered chromosomes derived from the DNA of a species. Discover the latest research on artificial chromosomes here.

© 2019 Meta ULC. All rights reserved
/feed-previews/crispr-for-genome-editing/108ea46b-9687-475e-a198-97943755becc