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CRISPR (general)

CRISPR (general) diagram by undefined

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

Top 20 most recent papers
Nature Communications

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Nature CommunicationsDecember 6, 2019
Hiroyuki MorisakaTomoji Mashimo
Nature Biotechnology

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Nature BiotechnologyDecember 9, 2019
David N. NguyenAlexander Marson

ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens

bioRxivDecember 8, 2019
Elizabeth R. Hutton, Adam C Siepel

Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

bioRxivDecember 10, 2019
Vinay Kumar BariAyala Meir

kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9

bioRxivDecember 8, 2019
Mahmudur Rahman HeraAtif Hasan Rahman

The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette
Scientific Reports

Essential role of the initial activation signal in isotype selection upon deletion of a transcriptionally committed promoter

Scientific ReportsDecember 6, 2019
Joana M SantosAhmed Amine Khamlichi

Comparative proximity biotinylation produces an inventory of RAB18-interactions and implicates RAB18 in cholesterol mobilization

bioRxivDecember 10, 2019
Robert Scott KissMark T W Handley
Plant Biotechnology Journal

Disruption of miRNA Sequences by TALENs and CRISPR/Cas9 Induces Varied Lengths of miRNA Production

Plant Biotechnology JournalDecember 10, 2019
Honghao BiBing Yang
Plant Physiology

MADS78 and MADS79 are essential regulators of early seed development in rice

Plant PhysiologyDecember 9, 2019
Puneet PaulHarkamal Walia

Chromosomal length reference assembly for Diaphorina citri using single-molecule sequencing and Hi-C proximity ligation with manually curated genes in developmental, structural and immune pathways

bioRxivDecember 10, 2019
Prashant S HosmaniSurya Saha

A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases

NatureDecember 9, 2019
Senén D MendozaJoseph Bondy-Denomy
Proceedings of the National Academy of Sciences of the United States of America

CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 9, 2019
Joanna JackowAngela M. Christiano
Molecular Therapy : the Journal of the American Society of Gene Therapy

Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model

Molecular Therapy : the Journal of the American Society of Gene TherapyNovember 18, 2019
Cristina GrangeBenedetta Bussolati
Nucleic Acids Research

Effector gene silencing mediated by histone methylation underpins host adaptation in an oomycete plant pathogen

Nucleic Acids ResearchDecember 10, 2019
Li-Yuan WangSuo-Meng Dong
Analytical Chemistry

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA

Analytical ChemistryDecember 9, 2019
Xiao Xia DaiYinsheng Wang
Scientific Reports

Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus

Scientific ReportsDecember 9, 2019
Jill M GoldsteinAmy J. Wagers

Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9.

bioRxivDecember 11, 2019
Kim M. SummersDavid Arthur Hume
Nature Microbiology

A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity

Nature MicrobiologyDecember 9, 2019
Lucía M MalonePeter C Fineran
Nature Communications

Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania

Nature CommunicationsDecember 9, 2019
Arijit BhattacharyaMarc Ouellette

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