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CRISPR (general)

CRISPR (general) diagram by Mari-Leaf, Shutterstock
Mari-Leaf, Shutterstock

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

Top 20 most recent papers

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

bioRxivJanuary 14, 2020
Emanuel GoncalvesMathew J Garnett
Trends in Plant Science

Revisiting the Role of Master Regulators in Tomato Ripening

Trends in Plant ScienceJanuary 14, 2020
Rufang WangRuud A de Maagd
Nature Biotechnology

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Nature BiotechnologyJanuary 15, 2020
Marco JostJonathan S Weissman

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
Journal of the American Chemical Society

Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks

Journal of the American Chemical SocietyJanuary 15, 2020
Mram Z AlyamiNiveen M Khashab

Genetic ablation of the mitochondrial ribosome in Plasmodium falciparum sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functions

bioRxivJanuary 14, 2020
Liqin LingHangjun Ke

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

bioRxivJanuary 14, 2020
Gopal KushawahMiguel Angel Moreno-Mateos

TOP the Transcription Orientation Pipeline and its use to investigate the transcription of non-coding regions: assessment with CRISPR direct repeats and intergenic sequences.

bioRxivJanuary 15, 2020
Kimberley HouenoussiChristine Pourcel

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

bioRxivJanuary 14, 2020
Carlee MacPherson CunninghamDarius Balciunas
Methods in Molecular Biology

CRISPR/Cas9-Based Genetic Screening to Study T-Cell Function

Methods in Molecular BiologyJanuary 15, 2020
Wanjing ShangHaopeng Wang
Nature Communications

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

Nature CommunicationsJanuary 16, 2020
Jinjin ShenDa Xing
Molecular Neurobiology

CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury

Molecular NeurobiologyJanuary 14, 2020
Vera PaschonAlexandre Hiroaki Kihara
Nano Letters

Single Virus Tracking with Quantum Dots Packaged into Enveloped Viruses Using CRISPR

Nano LettersJanuary 14, 2020
Yong-Bo YangTong-Qing An

Cas9/gRNA-mediated genome editing of yeast mitochondria and Chlamydomonas chloroplasts

PeerJJanuary 15, 2020
Byung-Chun YooHajime Sakai
International Journal of Biological Sciences

LRRC75A antisense lncRNA1 knockout attenuates inflammatory responses of bovine mammary epithelial cells

International Journal of Biological SciencesJanuary 14, 2020
Xixi WangMing-Qing Gao
Transgenic Research

Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs

Transgenic ResearchJanuary 14, 2020
Ruiqiang LiZuyong He

The better edge of the CRISPR blade

LancetJanuary 14, 2020
The Lancet
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

Abnormal expression of Wnt3a and inhibiting role of its molecular-targeted intervening in hepatocellular carcinoma

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatologyJanuary 17, 2020
W L SaiD F Yao
Nature Biomedical Engineering

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Nature Biomedical EngineeringJanuary 16, 2020
Hui Kwon KimHyongbum Henry Kim
Insect Biochemistry and Molecular Biology

The C-type lectin IML-10 promotes hemocytic encapsulation by enhancing aggregation of hemocytes in the Asian corn borer Ostrinia furnacalis

Insect Biochemistry and Molecular BiologyJanuary 14, 2020
Zhen-Kun SongJian Hu

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