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CRISPR (general)

CRISPR (general) diagram by Mari-Leaf, Shutterstock
Mari-Leaf, Shutterstock

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

Top 20 most recent papers
bioRxiv

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

bioRxivJanuary 14, 2020
Emanuel GoncalvesMathew J Garnett
60
Trends in Plant Science

Revisiting the Role of Master Regulators in Tomato Ripening

Trends in Plant ScienceJanuary 14, 2020
Rufang WangRuud A de Maagd
3
Nature Biotechnology

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Nature BiotechnologyJanuary 15, 2020
Marco JostJonathan S Weissman
118
1
bioRxiv

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
16
Journal of the American Chemical Society

Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks

Journal of the American Chemical SocietyJanuary 15, 2020
Mram Z AlyamiNiveen M Khashab
3
bioRxiv

Genetic ablation of the mitochondrial ribosome in Plasmodium falciparum sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functions

bioRxivJanuary 14, 2020
Liqin LingHangjun Ke
7
bioRxiv

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

bioRxivJanuary 14, 2020
Gopal KushawahMiguel Angel Moreno-Mateos
128
bioRxiv

TOP the Transcription Orientation Pipeline and its use to investigate the transcription of non-coding regions: assessment with CRISPR direct repeats and intergenic sequences.

bioRxivJanuary 15, 2020
Kimberley HouenoussiChristine Pourcel
6
bioRxiv

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

bioRxivJanuary 14, 2020
Carlee MacPherson CunninghamDarius Balciunas
13
Methods in Molecular Biology

CRISPR/Cas9-Based Genetic Screening to Study T-Cell Function

Methods in Molecular BiologyJanuary 15, 2020
Wanjing ShangHaopeng Wang
1
Nature Communications

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

Nature CommunicationsJanuary 16, 2020
Jinjin ShenDa Xing
12
Molecular Neurobiology

CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury

Molecular NeurobiologyJanuary 14, 2020
Vera PaschonAlexandre Hiroaki Kihara
1
Nano Letters

Single Virus Tracking with Quantum Dots Packaged into Enveloped Viruses Using CRISPR

Nano LettersJanuary 14, 2020
Yong-Bo YangTong-Qing An
2
PeerJ

Cas9/gRNA-mediated genome editing of yeast mitochondria and Chlamydomonas chloroplasts

PeerJJanuary 15, 2020
Byung-Chun YooHajime Sakai
7
International Journal of Biological Sciences

LRRC75A antisense lncRNA1 knockout attenuates inflammatory responses of bovine mammary epithelial cells

International Journal of Biological SciencesJanuary 14, 2020
Xixi WangMing-Qing Gao
Transgenic Research

Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs

Transgenic ResearchJanuary 14, 2020
Ruiqiang LiZuyong He
1
Lancet

The better edge of the CRISPR blade

LancetJanuary 14, 2020
The Lancet
20
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

Abnormal expression of Wnt3a and inhibiting role of its molecular-targeted intervening in hepatocellular carcinoma

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatologyJanuary 17, 2020
W L SaiD F Yao
Nature Biomedical Engineering

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Nature Biomedical EngineeringJanuary 16, 2020
Hui Kwon KimHyongbum Henry Kim
4
Insect Biochemistry and Molecular Biology

The C-type lectin IML-10 promotes hemocytic encapsulation by enhancing aggregation of hemocytes in the Asian corn borer Ostrinia furnacalis

Insect Biochemistry and Molecular BiologyJanuary 14, 2020
Zhen-Kun SongJian Hu

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