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CRISPR (general)

CRISPR (general) diagram by Mari-Leaf, Shutterstock
Mari-Leaf, Shutterstock

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchApril 5, 2020
James R WhittleGeoffrey J Lindeman
Nature Biotechnology

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

Nature BiotechnologyApril 2, 2020
Joseph M ReplogleBritt Adamson
110
Microbiology and Molecular Biology Reviews : MMBR

CRISPR Tools To Control Gene Expression in Bacteria

Microbiology and Molecular Biology Reviews : MMBRApril 3, 2020
Antoine Vigouroux, David Bikard
93
Molecular Therapy : the Journal of the American Society of Gene Therapy

Susceptibility to Cardiac Arrhythmias and Sympathetic Nerve Growth in VEGF-B Overexpressing Myocardium

Molecular Therapy : the Journal of the American Society of Gene TherapyApril 4, 2020
Johanna LähteenvuoSeppo Ylä-Herttuala
Molecular Therapy : the Journal of the American Society of Gene Therapy

Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

Molecular Therapy : the Journal of the American Society of Gene TherapyApril 4, 2020
Lydia TeboulGuillaume Pavlovic
The Journal of Biological Chemistry

Thyrocyte cell survival and adaptation to chronic endoplasmic reticulum stress due to misfolded thyroglobulin

The Journal of Biological ChemistryApril 4, 2020
Yoshiaki MorishitaPeter Arvan
Molecular Therapy : the Journal of the American Society of Gene Therapy

Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis

Molecular Therapy : the Journal of the American Society of Gene TherapyApril 5, 2020
Zhenyao ChenZhaoxia Wang
2
The Journal of Biological Chemistry

Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences

The Journal of Biological ChemistryApril 4, 2020
Vladimir MeklerKonstantin Severinov
3
bioRxiv

Resources for genome editing in livestock: Cas9-expressing chickens and pigs

bioRxivApril 2, 2020
Denise BartschBenjamin Schusser
5
Journal of Virology

CD21 (Complement Receptor 2) is the receptor for Epstein-Barr virus entry into T cells

Journal of VirologyApril 3, 2020
Nicholas A SmithRosemary Rochford
1
Molecular Therapy : the Journal of the American Society of Gene Therapy

Targeted Metabolic Reprogramming to Improve the Efficacy of Oncolytic Virus Therapy

Molecular Therapy : the Journal of the American Society of Gene TherapyApril 4, 2020
Barry E KennedyShashi A Gujar

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