CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

January 18, 2021
Open Access

Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential

The Journal of Biological Chemistry
Lekha E ManjunathSandeep M Eswarappa
January 20, 2021

Bitter Sensing TAS2R50 Mediates the trans -Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture

Journal of Agricultural and Food Chemistry
Johanna TirochVeronika Somoza
January 17, 2021

SeqCor: correct the effect of guide RNA sequences in clustered regularly interspaced short palindromic repeats/Cas9 screening by machine learning algorithm

Journal of Genetics and Genomics = Yi Chuan Xue Bao
Xiaojian LiuYi Wang
January 20, 2021
Open Access

Prime Editing Guide RNA Design Automation Using PINE-CONE

ACS Synthetic Biology
Kylie Standage-BeierXiao Wang
January 18, 2021
Preprint
Open Access

Correction of a CFTR/G542X Mutation Using CRISPR/Cas9 Editing in Ovine-bovine Interspecies Embryos

ResearchSquare
Zhiqiang FanIrina Polejaeva
January 17, 2021
Open Access

FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells

International Journal of Molecular Sciences
Shibnath GhatakSuniti Misra
January 20, 2021
Open Access

Omics: The way forward to enhance abiotic stress tolerance in Brassica napus L

GM Crops & Food
Ali RazaMirza Hasanuzzaman
January 20, 2021
Open Access

High-content imaging-based pooled CRISPR screens in mammalian cells

The Journal of Cell Biology
Xiaowei YanRonald D Vale
January 21, 2021
Open Access

Towards elucidating the structure, function, and druggability of coronavirus cis-acting RNA motifs

Postepy biochemii
Joanna Sztuba-Solinska, Devadatta Gosavi
January 21, 2021

Improving a Quantitative Trait in Rice by Multigene Editing with CRISPR-Cas9

Methods in Molecular Biology
Yesuf Teslim YimamYong Zhang
January 18, 2021
Open Access

A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins

The Journal of Biological Chemistry
Etsuko Shibata, Anindya Dutta
January 20, 2021
Open Access

Deletion of Cbl-b inhibits CD8+ T-cell exhaustion and promotes CAR T-cell function

Journal for Immunotherapy of Cancer
Jitendra KumarK Venuprasad
January 20, 2021

Cryptic sulfur incorporation in thioangucycline biosynthesis

Angewandte Chemie
Mingming CaoBen Shen
January 19, 2021

The Card1 nuclease provides defence during type-III CRISPR immunity

Nature
Jakob T RostølLuciano A Marraffini

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