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CRISPR (general)
Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.
Top 20 most recent papers
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
Nature CommunicationsDecember 6, 2019
Hiroyuki MorisakaTomoji Mashimo
34
4
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
Nature BiotechnologyDecember 9, 2019
David N. NguyenAlexander Marson
46
ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens
bioRxivDecember 8, 2019
Elizabeth R. Hutton, Adam C Siepel
21
Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca
bioRxivDecember 10, 2019
Vinay Kumar BariAyala Meir
7
kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9
bioRxivDecember 8, 2019
Mahmudur Rahman HeraAtif Hasan Rahman
6
The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis
bioRxivDecember 8, 2019
Nicholas A. WoodScot P Ouellette
5
Essential role of the initial activation signal in isotype selection upon deletion of a transcriptionally committed promoter
Scientific ReportsDecember 6, 2019
Joana M SantosAhmed Amine Khamlichi
Comparative proximity biotinylation produces an inventory of RAB18-interactions and implicates RAB18 in cholesterol mobilization
bioRxivDecember 10, 2019
Robert Scott KissMark T W Handley
3
Disruption of miRNA Sequences by TALENs and CRISPR/Cas9 Induces Varied Lengths of miRNA Production
Plant Biotechnology JournalDecember 10, 2019
Honghao BiBing Yang
2
MADS78 and MADS79 are essential regulators of early seed development in rice
Plant PhysiologyDecember 9, 2019
Puneet PaulHarkamal Walia
Chromosomal length reference assembly for Diaphorina citri using single-molecule sequencing and Hi-C proximity ligation with manually curated genes in developmental, structural and immune pathways
bioRxivDecember 10, 2019
Prashant S HosmaniSurya Saha
9
A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases
NatureDecember 9, 2019
Senén D MendozaJoseph Bondy-Denomy
425
4
1
3
CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
Proceedings of the National Academy of Sciences of the United States of AmericaDecember 9, 2019
Joanna JackowAngela M. Christiano
5
1
Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model
Molecular Therapy : the Journal of the American Society of Gene TherapyNovember 18, 2019
Cristina GrangeBenedetta Bussolati
Effector gene silencing mediated by histone methylation underpins host adaptation in an oomycete plant pathogen
Nucleic Acids ResearchDecember 10, 2019
Li-Yuan WangSuo-Meng Dong
17
YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA
Analytical ChemistryDecember 9, 2019
Xiao Xia DaiYinsheng Wang
1
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus
Scientific ReportsDecember 9, 2019
Jill M GoldsteinAmy J. Wagers
Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9.
bioRxivDecember 11, 2019
Kim M. SummersDavid Arthur Hume
1
A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity
Nature MicrobiologyDecember 9, 2019
Lucía M MalonePeter C Fineran
191
7
Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania
Nature CommunicationsDecember 9, 2019
Arijit BhattacharyaMarc Ouellette
24