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CRISPR Genome Editing & Therapy (Preprints)

CRISPR Genome Editing & Therapy (Preprints)   diagram by Kweon et al, PLOS One
Kweon et al, PLOS One

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

Top 20 most recent papers
bioRxiv

Genome editing in mammals using CRISPR type I-D nuclease

bioRxivMarch 15, 2020
Keishi OsakabeYuriko Osakabe
6
bioRxiv

JACKIE: Fast enumeration of single- and multi-copy CRISPR binding sites

bioRxivFebruary 28, 2020
Jacqueline Jufen Zhu, Albert Wu Cheng
14
80
bioRxiv

CRISPR-TAPE: protein-centric CRISPR guide design for targeted proteome engineering

bioRxivFebruary 26, 2020
Daniel P AndersonMatthew Andrew Child
18
bioRxiv

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

bioRxivFebruary 20, 2020
Anne Ramsay BowdenSteve Jackson
23
bioRxiv

Dppa2/4 Counteract De Novo Methylation to Establish a Permissive Epigenome for Development

bioRxivMarch 12, 2020
Jamie A Hackett, Kristjan Holm Gretarsson
50
bioRxiv

Multiplexed conditional genome editing with Cas12a in Drosophila

bioRxivFebruary 27, 2020
Fillip PortMichael Boutros
37

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