CRISPR Genome Editing & Therapy (Preprints)

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

March 24, 2020
Preprint
Open Access

Dynamic aqueous multiphase reaction system for simple, sensitive and quantitative one-pot CRISPR-Cas12a based molecular diagnosis

BioRxiv : the Preprint Server for Biology
Kun YinChangchun Liu
March 14, 2020
Preprint
Open Access

Targeted genome editing in Nicotiana tabacum using inducible CRISPR/Cas9 system

BioRxiv : the Preprint Server for Biology
Chong RenZhenchang Liang
March 13, 2020
Preprint
Open Access

Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce multiplex-mutagenesis and lipogenesis in Atlantic salmon (Salmo salar)

BioRxiv : the Preprint Server for Biology
yang jinFabian Grammes
July 6, 2020
Preprint
Open Access

The role of icIL-1RA type 1 in oral keratinocyte senescence and the development of the senescence associated secretory phenotype

BioRxiv : the Preprint Server for Biology
S. E. NiklanderKeith D Hunter
July 6, 2020
Preprint
Open Access

CRISPR-Cas9 integrates exogeneous sorting new recombinant DNA in the model tree Populus trichocarpa

BioRxiv : the Preprint Server for Biology
Ali MovahediQ. Zhuge
March 12, 2020
Preprint
Open Access

Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence

BioRxiv : the Preprint Server for Biology
Aleksei SamolygoMalcolm F White
July 3, 2020
Preprint
Open Access

Upgraded CRISPR/Cas9 Tools for Tissue-Specific Mutagenesis in Drosophila

BioRxiv : the Preprint Server for Biology
G. T. KoremanChun Han
May 16, 2020
Preprint
Open Access

Evolutionary Changes in Left-Right Visceral Asymmetry in Astyanax Cavefish

BioRxiv : the Preprint Server for Biology
L. MaWilliam R. Jeffery
March 15, 2020
Preprint
Open Access

Efficient Generation of Isogenic Primary Human Myeloid Cells using CRISPR-Cas9 Ribonucleoproteins

BioRxiv : the Preprint Server for Biology
Joseph HiattAlexander Marson
March 14, 2020
Preprint
Open Access

Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza

BioRxiv : the Preprint Server for Biology
Timothy R AbbottLei S Qi
March 27, 2020
Preprint
Open Access

Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay

MedRxiv : the Preprint Server for Health Sciences
J. P. BroughtonCharles Y Chiu
March 20, 2020
Preprint
Open Access

Bar-seq strategies for the LeishGEdit toolbox

BioRxiv : the Preprint Server for Biology
Tom Beneke, Eva Gluenz
June 2, 2020
Preprint
Open Access

Rapid and accurate detection of novel coronavirus SARS-CoV-2 using CRISPR-Cas3

MedRxiv : the Preprint Server for Health Sciences
K. YoshimiTomoji Mashimo
June 5, 2020
Preprint
Open Access

iSCAN: An RT-LAMP-coupled CRISPR-Cas12 module for rapid, sensitive detection of SARS-CoV-2

MedRxiv : the Preprint Server for Health Sciences
Z. AliMAGDY MAHFOUZ
March 15, 2020
Preprint
Open Access

A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

BioRxiv : the Preprint Server for Biology
Zurine AntonJon D Lane
March 15, 2020
Preprint
Open Access

Genome editing in mammals using CRISPR type I-D nuclease

BioRxiv : the Preprint Server for Biology
Keishi OsakabeYuriko Osakabe
July 7, 2020
Preprint
Open Access

A High-efficacy CRISPRi System for Gene Function Discovery in Zymomonas mobilis

BioRxiv : the Preprint Server for Biology
Jason M PetersC. Siletti
July 1, 2020
Preprint
Open Access

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

BioRxiv : the Preprint Server for Biology
X. YanRonald Vale
March 18, 2020
Preprint
Open Access

Discovering biomarkers of chemotherapy resistance using in vitro evolution in haploid human cells

BioRxiv : the Preprint Server for Biology
Juan Carlos JadoElizabeth Winzeler

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